STAG2 and ITGB1BP2

Number of citations of the paper that reports this interaction (PubMedID 23414517)
48

Data Source:
BioGRID (two hybrid)

		STAG2	ITGB1BP2
Description		STAG2 cohesin complex component	integrin subunit beta 1 binding protein 2
Image			No pdb structure
GO Annotations	Cellular Component	Chromosome, Centromeric Region Chromatin Fibrillar Center Nucleus Nucleoplasm Chromosome Nucleolus Cytosol Cohesin Complex Membrane Nuclear Matrix Mitotic Cohesin Complex Mitotic Spindle Pole	Z Disc
	Molecular Function	Chromatin Binding Protein Binding	Integrin Binding Calcium Ion Binding Protein Binding Zinc Ion Binding SH3 Domain Binding Metal Ion Binding
	Biological Process	Chromosome Segregation Sister Chromatid Cohesion Establishment Of Mitotic Sister Chromatid Cohesion Cell Division Meiotic Cell Cycle Mitotic Spindle Assembly	Signal Transduction Muscle Organ Development Centrosome Duplication
Pathways		Meiotic synapsis Separation of Sister Chromatids Establishment of Sister Chromatid Cohesion Cohesin Loading onto Chromatin Resolution of Sister Chromatid Cohesion SUMOylation of DNA damage response and repair proteins Estrogen-dependent gene expression
Drugs
Diseases
GWAS		Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494)
Interacting Genes		7 interacting genes: ITGB1BP2 PLK1 PTEN RAD21 SSU72 STAG1 SUMO2	14 interacting genes: HSP90AA1 HSP90AB1 ITGB1 PPHLN1 PUM3 RARA RARG SGCA SH3GLB1 STAG2 TKT TTN UGDH WASL
Entrez ID		10735	26548
HPRD ID		05077	02271
Ensembl ID		ENSG00000101972	ENSG00000147166
Uniprot IDs		Q8N3U4	Q9UKP3
PDB IDs		4PJU 4PJW 4PK7 6QNX 7ZJS 8K4D
Enriched GO Terms of Interacting Partners?		Sister Chromatid Cohesion Cohesin Complex Establishment Of Mitotic Sister Chromatid Cohesion Mitotic Cohesin Complex Establishment Of Sister Chromatid Cohesion Anaphase-promoting Complex Binding Positive Regulation Of Ubiquitin-dependent Protein Catabolic Process Chromosome Segregation Positive Regulation Of Proteolysis Involved In Protein Catabolic Process Spindle Organization Chromosome, Centromeric Region Negative Regulation Of Mitotic Cell Cycle Phase Transition Regulation Of Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Proteolysis Negative Regulation Of Mitotic Metaphase/anaphase Transition Negative Regulation Of Cell Cycle Phase Transition Negative Regulation Of Mitotic Cell Cycle Mitotic Spindle Pole Negative Regulation Of Mitotic Nuclear Division Negative Regulation Of Cell Cycle Process Protein Localization To Chromatin Chromosome Organization Regulation Of Mitotic Cell Cycle Phase Transition Regulation Of Mitotic Sister Chromatid Separation Negative Regulation Of Cell Cycle Negative Regulation Of G2/M Transition Of Mitotic Cell Cycle Negative Regulation Of Cell Cycle G2/M Phase Transition Regulation Of Proteolysis Regulation Of Chromosome Separation Negative Regulation Of Synaptic Vesicle Clustering Negative Regulation Of Chromosome Organization Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Protein Serine/threonine Phosphatase Activity Regulation Of Cell Cycle Phase Transition Microtubule Cytoskeleton Organization Regulation Of Mitotic Metaphase/anaphase Transition Cell Division Mitotic Spindle Organization Spindle Assembly Regulation Of Sister Chromatid Segregation Regulation Of Mitotic Cell Cycle Nucleoplasm Protein Localization To Chromosome Synaptonemal Complex Disassembly Golgi Inheritance Regulation Of G2/M Transition Of Mitotic Cell Cycle Phosphatidylinositol-3,4-bisphosphate 3-phosphatase Activity Negative Regulation Of Keratinocyte Migration Inositol-1,3,4,5-tetrakisphosphate 3-phosphatase Activity PML Body	Trachea Cartilage Development Glandular Epithelial Cell Development Telomerase Holoenzyme Complex Assembly Nitric-oxide Synthase Regulator Activity Dendritic Growth Cone TPR Domain Binding Growth Plate Cartilage Development Regulation Of Protein Localization Melanosome Protein Kinase Regulator Activity Columnar/cuboidal Epithelial Cell Development Embryonic Camera-type Eye Development Regulation Of Plasma Membrane Organization Chaperone-mediated Protein Complex Assembly Chromosome Organization Telomere Maintenance Via Telomerase Histone Deacetylase Binding DNA Polymerase Binding Cartilage Development Involved In Endochondral Bone Morphogenesis Retinoic Acid Receptor Signaling Pathway Face Development Protein Homodimerization Activity Axonal Growth Cone RNA-templated DNA Biosynthetic Process MHC Class II Protein Complex Binding Disordered Domain Specific Binding Protein-containing Complex Telomere Maintenance Via Telomere Lengthening Protein Folding Chaperone Complex Negative Regulation Of Cartilage Development Skeletal Muscle Contraction Positive Regulation Of Protein Localization ATP-dependent Protein Folding Chaperone Cardiac Muscle Cell Differentiation Positive Regulation Of Nitric Oxide Biosynthetic Process Protein Folding Muscle Contraction Positive Regulation Of Nitric Oxide Metabolic Process Extracellular Exosome Protein Tyrosine Kinase Binding Tau Protein Binding Supramolecular Fiber Organization Sarcomere Organization Regulation Of Myelination Anatomical Structure Morphogenesis CTP Binding DATP Binding Cellular Response To Heat Myoblast Fate Specification Cardiocyte Differentiation
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