RAD21 and SSU72

Number of citations of the paper that reports this interaction (PMID 20818333)
3

Data Source:
BioGRID (affinity chromatography technology, pull down, affinity chromatography technology)

		RAD21	SSU72
Gene Name		RAD21 homolog (S. pombe)	SSU72 RNA polymerase II CTD phosphatase homolog (S. cerevisiae)
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Chromosome, Centromeric Region Chromatin Nucleoplasm Chromosome Cytosol Cohesin Complex Membrane Nuclear Meiotic Cohesin Complex	Nucleus Cytoplasm
	Molecular Function	Protein Binding	Protein Binding CTD Phosphatase Activity
	Biological Process	Mitotic Cell Cycle Double-strand Break Repair DNA Recombination Regulation Of Transcription From RNA Polymerase II Promoter Apoptotic Process Chromosome Segregation Mitotic Nuclear Division Reciprocal Meiotic Recombination Cell Division Protein Localization To Chromatin	MRNA Polyadenylation Dephosphorylation Of RNA Polymerase II C-terminal Domain
Pathways		Establishment of Sister Chromatid Cohesion Mitotic Prometaphase Mitotic Telophase/Cytokinesis Separation of Sister Chromatids Meiotic synapsis Cohesin Loading onto Chromatin Mitotic Anaphase S Phase M Phase Cell Cycle, Mitotic Resolution of Sister Chromatid Cohesion Mitotic Metaphase and Anaphase
Drugs
Diseases
GWAS
Protein-Protein Interactions		28 interactors: CAPN1 CASP7 CFL1 COX2 CSTB DISC1 DYNLT1 FHL3 FLNB HNRNPH2 IL7R MSRB2 NUMA1 PPP1R15A PPP1R15B RPL10 RPL13 RPL35A SMARCA5 SMC1A SSU72 STAG1 STAG2 TMSB4X TNFRSF14 WAPAL WNT2B ZNF80	5 interactors: MAPK8 MAPK9 RAD21 STAG2 SYMPK
Entrez ID		5885	29101
HPRD ID		05924	13712
Ensembl ID		ENSG00000164754	ENSG00000160075
Uniprot IDs		O60216	Q9NP77
PDB IDs			3O2Q 3O2S 4H3H 4H3K
Enriched GO Terms of Interacting Partners?		Cell Division Mitotic Nuclear Division Cellular Protein Localization Viral Life Cycle Cytoskeleton Organization Mitotic Cell Cycle Process Negative Regulation Of DNA Endoreduplication Protein Localization To Endoplasmic Reticulum Cell Cycle Process Mitotic Cell Cycle Organelle Organization Protein Localization To Organelle Negative Regulation Of DNA Replication MRNA Metabolic Process Viral Process Protein Localization Cellular Localization Cellular Protein Complex Disassembly Regulation Of DNA Endoreduplication Protein Complex Disassembly Cell Cycle Negative Regulation Of Cell Cycle Viral Transcription Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay SRP-dependent Cotranslational Protein Targeting To Membrane Establishment Of Cell Polarity Negative Regulation Of DNA Metabolic Process Cotranslational Protein Targeting To Membrane Protein Targeting To ER Establishment Of Protein Localization To Endoplasmic Reticulum Regulation Of DNA Replication Sister Chromatid Cohesion Establishment Of Mitotic Spindle Orientation Actin Cytoskeleton Organization Translational Termination Establishment Of Mitotic Spindle Localization Establishment Of Spindle Orientation Establishment Of Protein Localization To Organelle Nuclear-transcribed MRNA Catabolic Process Actin Filament-based Process MRNA Catabolic Process Protein Targeting To Membrane Establishment Or Maintenance Of Cell Polarity Viral Entry Into Host Cell Translational Elongation Spindle Localization Regulation Of Metabolic Process Entry Into Host Cell RNA Catabolic Process Positive Regulation Of Translational Initiation In Response To Stress	JUN Phosphorylation Toll-like Receptor 5 Signaling Pathway Toll-like Receptor 10 Signaling Pathway Response To Cadmium Ion Toll-like Receptor TLR6:TLR2 Signaling Pathway Toll-like Receptor TLR1:TLR2 Signaling Pathway Toll-like Receptor 2 Signaling Pathway Toll-like Receptor 9 Signaling Pathway TRIF-dependent Toll-like Receptor Signaling Pathway MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway MyD88-dependent Toll-like Receptor Signaling Pathway Toll-like Receptor 4 Signaling Pathway JNK Cascade Regulation Of Circadian Rhythm Toll-like Receptor Signaling Pathway Stress-activated MAPK Cascade Stress-activated Protein Kinase Signaling Cascade Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Response To UV Activation Of Innate Immune Response Cellular Response To Lipopolysaccharide Cellular Response To Molecule Of Bacterial Origin Positive Regulation Of Innate Immune Response Apoptotic Process Positive Regulation Of Apoptotic Signaling Pathway Programmed Cell Death Meiotic Cell Cycle Cell Death Response To Mechanical Stimulus Death MAPK Cascade Fc-epsilon Receptor Signaling Pathway Chromosome Segregation Negative Regulation Of DNA Endoreduplication Regulation Of Innate Immune Response Positive Regulation Of Deacetylase Activity Positive Regulation Of Prostaglandin Biosynthetic Process Fc Receptor Signaling Pathway Signal Transduction By Phosphorylation Positive Regulation Of Determination Of Dorsal Identity Response To Lipopolysaccharide Mitotic Nuclear Division Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Response To Metal Ion Response To Molecule Of Bacterial Origin Response To Light Stimulus Apoptotic Signaling Pathway Regulation Of DNA Endoreduplication
Tagcloud ?		aberrations apart aspect ccnd1 clinicopathological copy covered encompassed endometrial erbb1 erbb2 erbb3 erbb4 esr1 frequent infiltration insufficient myometrial pakt1 pgr pik3ca prom1 rad27 runx1 scgb2a2 snai1 snai2 top2a younger	alleles choose cleavage conversely degrades disrupt elongation exonuclease exosome generates keeps localize nrd1 nucleolar options pcf11 poly polyadenylated polyadenylation rat1 rnas sen1 snorna snornas termination transcribed transcribing trimming xrn2
Tagcloud (Difference) ?		aberrations apart aspect ccnd1 clinicopathological copy covered encompassed endometrial erbb1 erbb2 erbb3 erbb4 esr1 frequent infiltration insufficient myometrial pakt1 pgr pik3ca prom1 rad27 runx1 scgb2a2 snai1 snai2 top2a younger	alleles choose cleavage conversely degrades disrupt elongation exonuclease exosome generates keeps localize nrd1 nucleolar options pcf11 poly polyadenylated polyadenylation rat1 rnas sen1 snorna snornas termination transcribed transcribing trimming xrn2
Tagcloud (Intersection) ?