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RAD21 and HNRNPH2
Number of citations of the paper that reports this interaction (PubMedID
22145905
)
0
Data Source:
BioGRID
(two hybrid)
RAD21
HNRNPH2
Description
RAD21 cohesin complex component
heterogeneous nuclear ribonucleoprotein H2
Image
GO Annotations
Cellular Component
Chromosome, Centromeric Region
Chromatin
Condensed Nuclear Chromosome
Spindle Pole
Nucleus
Nucleoplasm
Chromosome
Cytoplasm
Cytosol
Cytoskeleton
Cohesin Complex
Membrane
Nuclear Matrix
Midbody
Mitotic Cohesin Complex
Meiotic Cohesin Complex
Nucleus
Nucleoplasm
Cytosol
Membrane
Ribonucleoprotein Complex
Molecular Function
Cis-regulatory Region Sequence-specific DNA Binding
DNA Binding
Chromatin Binding
Protein Binding
LncRNA Binding
DNA-binding Transcription Factor Binding
Nucleic Acid Binding
RNA Binding
Protein Binding
Biological Process
Response To Hypoxia
DNA Repair
Double-strand Break Repair
DNA Recombination
Regulation Of Transcription By RNA Polymerase II
Apoptotic Process
DNA Damage Response
Chromosome Segregation
Sister Chromatid Cohesion
Reciprocal Meiotic Recombination
Positive Regulation Of Gene Expression
Negative Regulation Of Gene Expression
Negative Regulation Of G2/M Transition Of Mitotic Cell Cycle
Negative Regulation Of Interleukin-1 Beta Production
Negative Regulation Of Tumor Necrosis Factor Production
Positive Regulation Of Interleukin-10 Production
Establishment Of Mitotic Sister Chromatid Cohesion
Establishment Of Meiotic Sister Chromatid Cohesion
Negative Regulation Of Glial Cell Apoptotic Process
Negative Regulation Of Neuron Apoptotic Process
Negative Regulation Of Mitotic Metaphase/anaphase Transition
Positive Regulation Of Sister Chromatid Cohesion
Cell Division
Protein Localization To Chromatin
Chromatin Looping
Replication-born Double-strand Break Repair Via Sister Chromatid Exchange
Regulation Of RNA Splicing
Pathways
Meiotic synapsis
Separation of Sister Chromatids
Establishment of Sister Chromatid Cohesion
Cohesin Loading onto Chromatin
Resolution of Sister Chromatid Cohesion
SUMOylation of DNA damage response and repair proteins
Estrogen-dependent gene expression
mRNA Splicing - Major Pathway
Processing of Capped Intron-Containing Pre-mRNA
Drugs
Diseases
GWAS
Menopause (age at onset) (
29773799
)
Interacting Genes
30 interacting genes:
CAPN1
CASP7
CFL1
CSTB
DISC1
DYNLT1
FHL3
FLNB
HNRNPH2
IL7R
MSRB2
MT-CO2
NUMA1
PPP1R15A
PPP1R15B
PTEN
RPL10
RPL13
RPL35A
SMARCA5
SMC1A
SSU72
STAG1
STAG2
SUMO2
TMSB4X
TNFRSF14
WAPL
WNT2B
ZNF80
97 interacting genes:
CCNK
DDX5
FXR1
HNRNPA0
HNRNPUL1
HSF2BP
ILF3
MIR1-1
MIR1-2
MIR106A
MIR106B
MIR107
MIR122
MIR128-1
MIR128-2
MIR138-1
MIR138-2
MIR140
MIR141
MIR143
MIR145
MIR155
MIR15A
MIR15B
MIR16-1
MIR16-2
MIR17
MIR18B
MIR199A1
MIR199A2
MIR19A
MIR19B1
MIR19B2
MIR200A
MIR200B
MIR200C
MIR205
MIR206
MIR20A
MIR20B
MIR21
MIR214
MIR221
MIR222
MIR25
MIR29A
MIR29B1
MIR29B2
MIR29C
MIR31
MIR34A
MIR34B
MIR34C
MIR363
MIR429
MIR451A
MIR7-1
MIR7-2
MIR7-3
MIR9-1
MIR9-2
MIR9-3
MIR92A1
MIR92A2
MIR93
MIR98
MIRLET7A1
MIRLET7A2
MIRLET7A3
MIRLET7B
MIRLET7C
MIRLET7D
MIRLET7E
MIRLET7F1
MIRLET7F2
MIRLET7G
MIRLET7I
MSI1
MSI2
OGT
PQBP1
PRMT6
PRPF31
PRPF8
QKI
RACK1
RAD21
RBFOX2
RBM10
RBM4
SF1
SNRPC
SUMO2
TEKT1
TLE5
WDR83
WEE2-AS1
Entrez ID
5885
3188
HPRD ID
05924
03022
Ensembl ID
ENSG00000164754
ENSG00000126945
Uniprot IDs
O60216
A0A384MDT2
P55795
PDB IDs
4PJU
4PJW
4PK7
6QNX
6RRC
6RRK
6WG3
6WGE
7W1M
7ZJS
8K4D
8P0A
8PQ5
8RO6
8RO7
8RO8
8RO9
8ROA
8ROB
8ROC
8ROD
8ROE
8ROF
8ROG
8ROH
8ROI
8ROJ
8ROK
8ROL
1WEZ
1WG5
6DG1
8SGH
Enriched GO Terms of Interacting Partners
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Cohesin Complex
Establishment Of Mitotic Sister Chromatid Cohesion
Mitotic Cohesin Complex
Establishment Of Sister Chromatid Cohesion
Mitotic Spindle Pole
Spindle Assembly
Microtubule Cytoskeleton Organization
Nuclear Matrix
Microtubule Cytoskeleton Organization Involved In Mitosis
Cytoskeleton Organization
Chromosome Segregation
Spindle Organization
Cytosol
Microtubule-based Process
Sister Chromatid Cohesion
Mitotic Spindle Assembly
Negative Regulation Of Cell Size
Membraneless Organelle Assembly
Cell Division
Establishment Of Spindle Localization
Cytosolic Large Ribosomal Subunit
RNA Binding
Spindle Localization
Chromosome, Centromeric Region
Negative Regulation Of PERK-mediated Unfolded Protein Response
Protein Phosphatase Type 1 Complex
Regulation Of PERK-mediated Unfolded Protein Response
Regulation Of Cell Size
Positive Regulation Of Proteolysis
Actin Binding
Regulation Of Proteolysis
Mitotic Spindle Organization
Cytosolic Ribosome
Negative Regulation Of Endoplasmic Reticulum Unfolded Protein Response
Positive Regulation Of Ubiquitin-dependent Protein Catabolic Process
Ficolin-1-rich Granule Lumen
Cofilin-actin Rod
Negative Regulation Of Unidimensional Cell Growth
Positive Regulation Of Establishment Of Cell Polarity Regulating Cell Shape
Regulation Of Cellular Component Size
Positive Regulation Of Barbed-end Actin Filament Capping
Regulation Of Cell-matrix Adhesion
Positive Regulation Of Protein Localization To Cell Leading Edge
Cortical Microtubule
Meiotic Cell Cycle
Anastral Spindle Assembly
Cytoplasmic Microtubule Bundle
Positive Regulation Of Protein Localization To Spindle Pole Body
Chromosome
Organelle Assembly
MiRNA-mediated Post-transcriptional Gene Silencing
Regulatory NcRNA-mediated Post-transcriptional Gene Silencing
RISC Complex
Post-transcriptional Gene Silencing
Regulatory NcRNA-mediated Gene Silencing
MRNA Base-pairing Post-transcriptional Repressor Activity
Post-transcriptional Regulation Of Gene Expression
Negative Regulation Of Gene Expression
MRNA 3'-UTR Binding
Negative Regulation Of Biosynthetic Process
Negative Regulation Of Macromolecule Biosynthetic Process
MiRNA-mediated Gene Silencing By Inhibition Of Translation
Negative Regulation Of Macromolecule Metabolic Process
Negative Regulation Of Metabolic Process
Negative Regulation Of Translation
MiRNA-mediated Gene Silencing By MRNA Destabilization
Extracellular Vesicle
Regulation Of Gene Expression
Regulation Of Macromolecule Biosynthetic Process
Regulation Of Translation
Negative Regulation Of Cytokine Production
Positive Regulation Of MRNA Catabolic Process
MRNA Destabilization
Regulation Of Macromolecule Metabolic Process
RNA Destabilization
Regulation Of Metabolic Process
Negative Regulation Of Cell Migration
Positive Regulation Of MRNA Metabolic Process
Regulation Of MRNA Stability
Negative Regulation Of Cell Motility
Negative Regulation Of Locomotion
Negative Regulation Of Angiogenesis
Negative Regulation Of Vasculature Development
Regulation Of RNA Stability
Negative Regulation Of Vascular Endothelial Growth Factor Production
Negative Regulation Of Protein Metabolic Process
Regulation Of Angiogenesis
Regulation Of MRNA Metabolic Process
Regulation Of Vasculature Development
Negative Regulation Of Multicellular Organismal Process
Regulation Of Cytokine Production
Negative Regulation Of Developmental Process
Regulation Of Blood Vessel Endothelial Cell Migration
Negative Regulation Of Blood Vessel Endothelial Cell Migration
Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway
Negative Regulation Of Endothelial Cell Migration
Regulation Of Cell Migration
Regulation Of Endothelial Cell Migration
Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway
Regulation Of Cell Motility
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