CETN3 and TNNI1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		CETN3	TNNI1
Description		centrin 3	troponin I1, slow skeletal type
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nuclear Envelope Nuclear Pore Nucleolus Cytoplasm Centrosome Centriole Microtubule Organizing Center Cytoskeleton Photoreceptor Connecting Cilium Ciliary Transition Zone Ciliary Basal Body Nuclear Pore Nuclear Basket Transcription Export Complex 2	Cytosol Troponin Complex
	Molecular Function	Calcium Ion Binding Protein Binding Microtubule Binding G-protein Beta/gamma-subunit Complex Binding Metal Ion Binding	Actin Binding Protein Binding
	Biological Process	Microtubule Cytoskeleton Organization Centrosome Cycle Protein Transport MRNA Transport Cell Division	Skeletal Muscle Contraction Regulation Of Striated Muscle Contraction Transition Between Fast And Slow Fiber Ventricular Cardiac Muscle Tissue Morphogenesis Cardiac Muscle Contraction
Pathways			Striated Muscle Contraction
Drugs
Diseases
GWAS		Rosacea symptom severity ( 29771307) Serum alkaline phosphatase levels ( 33547301) Type 2 diabetes ( 19734900)
Interacting Genes		14 interacting genes: AGR2 CKMT2 HSPB1 IKBKG LDB2 LMNA LRIF1 LRRK2 MFHAS1 PDE6D RCN1 SGK1 TNNI1 UNC119	46 interacting genes: ACTA1 ANKRD11 ARMC7 C2orf68 CABP2 CABP5 CCDC102B CCDC57 CCDC85B CDCA7L CEP19 CETN3 CTNNA3 DCAF11 DRC8 EAF1 EIF1AD EIF3B ENKD1 ESRRG KIFC3 L3MBTL2 MBD3 MCRS1 MDFI MNS1 MTUS2 PIH1D2 PIK3R3 PKD2L1 PNMA1 POLR1C PRKAB2 SAT1 SCNM1 SPANXN2 SYCE1L TNNC1 TNNT1 TNNT2 TPM3 TRIM41 TRIM55 TRIM63 USP20 ZNF76
Entrez ID		1070	7135
HPRD ID		04216	01842
Ensembl ID		ENSG00000153140	ENSG00000159173
Uniprot IDs		E5RFM2 E5RJF8 O15182	P19237
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Apoptotic Signaling Pathway Regulation Of Response To Endoplasmic Reticulum Stress Negative Regulation Of Intrinsic Apoptotic Signaling Pathway Negative Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway System Process Protein Folding Regulation Of Programmed Cell Death Regulation Of Apoptotic Process Regulation Of Phosphorus Metabolic Process Regulation Of Apoptotic Signaling Pathway Protein Folding Chaperone Negative Regulation Of Protein Kinase C Signaling Negative Regulation Of Programmed Cell Death Negative Regulation Of Apoptotic Process Regulation Of Intrinsic Apoptotic Signaling Pathway Intracellular Protein Transport HSP90-CDC37 Chaperone Complex Regulation Of Ubiquitin-dependent Protein Catabolic Process Regulation Of Protein Localization Developmental Process DNA Double-strand Break Attachment To Nuclear Envelope Regulation Of System Process Structural Constituent Of Nuclear Lamina Visual Perception Sensory Perception Of Light Stimulus Regulation Of Catalytic Activity Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway Negative Regulation Of Response To Endoplasmic Reticulum Stress Negative Regulation Of Caveolin-mediated Endocytosis Regulation Of Macrophage Activation Cellular Response To Curcumin Caveola Neck Negative Regulation Of Late Endosome To Lysosome Transport Amphisome Peroxidase Inhibitor Activity Negative Regulation Of Protein Processing Involved In Protein Targeting To Mitochondrion Protein Localization To Mitochondrion GTP-dependent Protein Kinase Activity Beta-catenin Destruction Complex Binding Wnt Signalosome Assembly Cellular Response To Stress Mitochondrion Response To Unfolded Protein Regulation Of Locomotion Protein Transport Response To Heat Regulation Of Protein Modification Process Protein Kinase C Inhibitor Activity Ubiquitin Protein Ligase Binding Linear Polyubiquitin Binding	Cytoskeleton Troponin Complex Centrosome Muscle Contraction Cardiac Troponin Complex Troponin I Binding Troponin T Binding Muscle System Process Centriole Transition Between Fast And Slow Fiber Striated Muscle Thin Filament Microtubule Regulation Of Skeletal Muscle Adaptation Sarcomere Contractile Muscle Fiber Tropomyosin Binding Regulation Of Muscle System Process Cytoplasm Muscle Filament Sliding Protein Binding Actin-myosin Filament Sliding Spindle Pole
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