CETN3 and CKMT2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		CETN3	CKMT2
Description		centrin 3	creatine kinase, mitochondrial 2
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nuclear Envelope Nuclear Pore Nucleolus Cytoplasm Centrosome Centriole Microtubule Organizing Center Cytoskeleton Photoreceptor Connecting Cilium Ciliary Transition Zone Ciliary Basal Body Nuclear Pore Nuclear Basket Transcription Export Complex 2	Mitochondrion Mitochondrial Inner Membrane Membrane
	Molecular Function	Calcium Ion Binding Protein Binding Microtubule Binding G-protein Beta/gamma-subunit Complex Binding Metal Ion Binding	Nucleotide Binding Catalytic Activity Creatine Kinase Activity Protein Binding ATP Binding Kinase Activity Transferase Activity Transferase Activity, Transferring Phosphorus-containing Groups
	Biological Process	Microtubule Cytoskeleton Organization Centrosome Cycle Protein Transport MRNA Transport Cell Division	Muscle Contraction Phosphocreatine Biosynthetic Process
Pathways			Creatine metabolism
Drugs			Creatine Phosphocreatine
Diseases
GWAS		Rosacea symptom severity ( 29771307) Serum alkaline phosphatase levels ( 33547301) Type 2 diabetes ( 19734900)
Interacting Genes		14 interacting genes: AGR2 CKMT2 HSPB1 IKBKG LDB2 LMNA LRIF1 LRRK2 MFHAS1 PDE6D RCN1 SGK1 TNNI1 UNC119	10 interacting genes: ABHD6 CETN3 ELN KLHL42 LRIF1 NRF1 OLFML3 P4HA3 TMED9 UNC119
Entrez ID		1070	1160
HPRD ID		04216	00425
Ensembl ID		ENSG00000153140	ENSG00000131730
Uniprot IDs		E5RFM2 E5RJF8 O15182	P17540
PDB IDs			4Z9M
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Apoptotic Signaling Pathway Regulation Of Response To Endoplasmic Reticulum Stress Negative Regulation Of Intrinsic Apoptotic Signaling Pathway Negative Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway System Process Protein Folding Regulation Of Programmed Cell Death Regulation Of Apoptotic Process Regulation Of Phosphorus Metabolic Process Regulation Of Apoptotic Signaling Pathway Protein Folding Chaperone Negative Regulation Of Protein Kinase C Signaling Negative Regulation Of Programmed Cell Death Negative Regulation Of Apoptotic Process Regulation Of Intrinsic Apoptotic Signaling Pathway Intracellular Protein Transport HSP90-CDC37 Chaperone Complex Regulation Of Ubiquitin-dependent Protein Catabolic Process Regulation Of Protein Localization Developmental Process DNA Double-strand Break Attachment To Nuclear Envelope Regulation Of System Process Structural Constituent Of Nuclear Lamina Visual Perception Sensory Perception Of Light Stimulus Regulation Of Catalytic Activity Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway Negative Regulation Of Response To Endoplasmic Reticulum Stress Negative Regulation Of Caveolin-mediated Endocytosis Regulation Of Macrophage Activation Cellular Response To Curcumin Caveola Neck Negative Regulation Of Late Endosome To Lysosome Transport Amphisome Peroxidase Inhibitor Activity Negative Regulation Of Protein Processing Involved In Protein Targeting To Mitochondrion Protein Localization To Mitochondrion GTP-dependent Protein Kinase Activity Beta-catenin Destruction Complex Binding Wnt Signalosome Assembly Cellular Response To Stress Mitochondrion Response To Unfolded Protein Regulation Of Locomotion Protein Transport Response To Heat Regulation Of Protein Modification Process Protein Kinase C Inhibitor Activity Ubiquitin Protein Ligase Binding Linear Polyubiquitin Binding
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