CETN3 and RCN1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		CETN3	RCN1
Description		centrin 3	reticulocalbin 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nuclear Envelope Nuclear Pore Nucleolus Cytoplasm Centrosome Centriole Microtubule Organizing Center Cytoskeleton Photoreceptor Connecting Cilium Ciliary Transition Zone Ciliary Basal Body Nuclear Pore Nuclear Basket Transcription Export Complex 2	Endoplasmic Reticulum Endoplasmic Reticulum Lumen
	Molecular Function	Calcium Ion Binding Protein Binding Microtubule Binding G-protein Beta/gamma-subunit Complex Binding Metal Ion Binding	Calcium Ion Binding Protein Binding Metal Ion Binding
	Biological Process	Microtubule Cytoskeleton Organization Centrosome Cycle Protein Transport MRNA Transport Cell Division	In Utero Embryonic Development Camera-type Eye Development
Pathways			Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Post-translational protein phosphorylation
Drugs
Diseases
GWAS		Rosacea symptom severity ( 29771307) Serum alkaline phosphatase levels ( 33547301) Type 2 diabetes ( 19734900)	Apolipoprotein B levels ( 32203549) Basophil count ( 32888494) Blood protein levels ( 30072576) Body mass index ( 28371326) General factor of neuroticism ( 30867560) Major depressive disorder ( 27479909) Metabolite levels (HVA/5-HIAA ratio) ( 23319000) Refractive error ( 32231278)
Interacting Genes		14 interacting genes: AGR2 CKMT2 HSPB1 IKBKG LDB2 LMNA LRIF1 LRRK2 MFHAS1 PDE6D RCN1 SGK1 TNNI1 UNC119	19 interacting genes: ASB8 ASPH ATPAF2 ATXN1 CETN3 DCAF11 EFHC1 ENKD1 FAM110A GADD45G LMO1 LMO2 LMO3 LMO4 MYO15B PTEN SGTA SGTB ZNF410
Entrez ID		1070	5954
HPRD ID		04216	04111
Ensembl ID		ENSG00000153140	ENSG00000049449
Uniprot IDs		E5RFM2 E5RJF8 O15182	Q15293 V9HW95
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Apoptotic Signaling Pathway Regulation Of Response To Endoplasmic Reticulum Stress Negative Regulation Of Intrinsic Apoptotic Signaling Pathway Negative Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway System Process Protein Folding Regulation Of Programmed Cell Death Regulation Of Apoptotic Process Regulation Of Phosphorus Metabolic Process Regulation Of Apoptotic Signaling Pathway Protein Folding Chaperone Negative Regulation Of Protein Kinase C Signaling Negative Regulation Of Programmed Cell Death Negative Regulation Of Apoptotic Process Regulation Of Intrinsic Apoptotic Signaling Pathway Intracellular Protein Transport HSP90-CDC37 Chaperone Complex Regulation Of Ubiquitin-dependent Protein Catabolic Process Regulation Of Protein Localization Developmental Process DNA Double-strand Break Attachment To Nuclear Envelope Regulation Of System Process Structural Constituent Of Nuclear Lamina Visual Perception Sensory Perception Of Light Stimulus Regulation Of Catalytic Activity Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway Negative Regulation Of Response To Endoplasmic Reticulum Stress Negative Regulation Of Caveolin-mediated Endocytosis Regulation Of Macrophage Activation Cellular Response To Curcumin Caveola Neck Negative Regulation Of Late Endosome To Lysosome Transport Amphisome Peroxidase Inhibitor Activity Negative Regulation Of Protein Processing Involved In Protein Targeting To Mitochondrion Protein Localization To Mitochondrion GTP-dependent Protein Kinase Activity Beta-catenin Destruction Complex Binding Wnt Signalosome Assembly Cellular Response To Stress Mitochondrion Response To Unfolded Protein Regulation Of Locomotion Protein Transport Response To Heat Regulation Of Protein Modification Process Protein Kinase C Inhibitor Activity Ubiquitin Protein Ligase Binding Linear Polyubiquitin Binding	TRC Complex Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Microtubule Cytoskeleton Organization Microtubule Cytoskeleton Organization Involved In Mitosis Positive Regulation Of RNA Metabolic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process DNA-binding Transcription Factor Binding Post-translational Protein Targeting To Endoplasmic Reticulum Membrane Positive Regulation Of Transcription By RNA Polymerase II Cytoskeleton Organization Regulation Of Organ Growth Positive Regulation Of Metabolic Process Microtubule-based Process Positive Regulation Of Macromolecule Biosynthetic Process Protein Targeting To ER Positive Regulation Of Macromolecule Metabolic Process Establishment Of Protein Localization To Endoplasmic Reticulum Positive Regulation Of Biosynthetic Process Establishment Of Mitotic Spindle Orientation Forebrain-midbrain Boundary Formation Pancreatic A Cell Development Establishment Of Mitotic Spindle Localization Negative Regulation Of Synaptic Vesicle Clustering Spindle Organization Spindle Pole Transcription Coregulator Binding
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