KLF1 and CSNK2A2

Number of citations of the paper that reports this interaction (PMID 9722526)
15

Data Source:
HPRD (in vitro, in vivo)

		KLF1	CSNK2A2
Gene Name		Kruppel-like factor 1 (erythroid)	casein kinase 2, alpha prime polypeptide
Image
Gene Ontology Annotations	Cellular Component	Nuclear Chromatin Nucleus	Nucleus Cytosol PcG Protein Complex
	Molecular Function	Core Promoter Proximal Region Sequence-specific DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Transcription Regulatory Region DNA Binding Metal Ion Binding	Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Protein N-terminus Binding
	Biological Process	In Utero Embryonic Development Liver Development Chromatin Remodeling Transcription, DNA-templated Erythrocyte Differentiation Embryonic Hemopoiesis Erythrocyte Maturation Positive Regulation Of Transcription, DNA-templated Cellular Response To Peptide	Mitotic Cell Cycle Transcription, DNA-templated Regulation Of Transcription, DNA-templated Protein Phosphorylation Apoptotic Process Axon Guidance Wnt Signaling Pathway Mitotic Spindle Checkpoint
Pathways			Mitotic Prometaphase Signal transduction by L1 Axon guidance misspliced LRP5 mutants have enhanced beta-catenin-dependent signaling L1CAM interactions Signaling by Wnt Cell Cycle, Mitotic M Phase WNT mediated activation of DVL TCF dependent signaling in response to WNT RNF mutants show enhanced WNT signaling and proliferation XAV939 inhibits tankyrase, stabilizing AXIN Signaling by WNT in cancer Condensation of Prometaphase Chromosomes
Drugs
Diseases
GWAS
Protein-Protein Interactions		14 interactors: ARID1A CREBBP CSNK2A1 CSNK2A2 EP300 FLI1 HDAC1 PRKACA SMARCA4 SMARCB1 SMARCC1 SMARCC2 SMARCD1 SMARCE1	92 interactors: ABCA1 ACACA ADH1A AQP4 ARR3 ARRB2 ASL ATF1 ATF2 BID CABP1 CALM1 CASQ2 CAV1 CDC37 CLTB CREBBP CREM CSN3 CSNK2B CTDP1 DCPS EEF1B2 EIF2B2 EIF2B5 EIF4EBP1 ERH FGF1 FGF2 FKBP3 FOS GTF2A1 GTF2A1L HDAC1 HDAC2 HDAC6 HIST1H1C HMGA1 HMGA2 HNRNPC HSP90AA1 HSP90B1 HSPH1 IL16 JUN KIF1C KLF1 LAMC3 LGALS3 MAF1 MAPK14 MGMT MS4A1 MYC MYCN MYF5 NAP1L4 NCL P4HB PAK1 PIN1 PIN4 PPP1R1B PPP1R2 PPP1R8 PRNP PTEN PTPN1 PTPRC RELA RGS19 SAT1 SLC18A2 SMURF1 SNCA SNX6 SPIB SPP1 STX1A TCF7L2 TCOF1 TGFBR1 TGM2 TOP1 TRIM41 TTLL12 UBE2R2 WAS XRCC1 ZNF219 ZNF670 ZNHIT3
Entrez ID		10661	1459
HPRD ID		07197	00279
Ensembl ID		ENSG00000105610	ENSG00000070770
Uniprot IDs		Q13351	P19784
PDB IDs		2L2I	3E3B 3OFM 3U87
Enriched GO Terms of Interacting Partners?		Nucleosome Disassembly Chromatin Modification ATP-dependent Chromatin Remodeling Chromatin Organization Chromatin Remodeling Chromosome Organization Nucleosome Organization Chromatin Assembly Or Disassembly Protein Complex Disassembly Positive Regulation Of Cellular Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter Multicellular Organismal Development Positive Regulation Of Transcription, DNA-templated Anatomical Structure Development Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Developmental Process System Development Nervous System Development Transcription, DNA-templated Regulation Of Transcription, DNA-templated Interaction With Symbiont RNA Biosynthetic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Positive Regulation Of Metabolic Process Gene Expression Positive Regulation Of Cellular Metabolic Process Regulation Of Gene Expression Positive Regulation By Host Of Viral Transcription Negative Regulation Of Cellular Metabolic Process Organelle Organization Regulation Of Viral Transcription RNA Metabolic Process Anatomical Structure Morphogenesis Regulation Of Metabolic Process Regulation Of Androgen Receptor Signaling Pathway Negative Regulation Of Biosynthetic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Biosynthetic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter N-terminal Peptidyl-lysine Acetylation Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Embryo Development Regulation Of Viral Process	Response To Organic Substance Regulation Of Metabolic Process Positive Regulation Of Cellular Metabolic Process Response To Stress Response To Abiotic Stimulus Response To Organonitrogen Compound Positive Regulation Of Metabolic Process Cellular Metabolic Process Positive Regulation Of Cellular Biosynthetic Process Cellular Response To Stimulus Regulation Of Gene Expression Developmental Process Innate Immune Response Cellular Response To Organic Substance Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Protein Metabolic Process Regulation Of Immune System Process Response To Growth Factor Enzyme Linked Receptor Protein Signaling Pathway Tissue Development Regulation Of Signal Transduction Regulation Of Nitrogen Compound Metabolic Process Response To Stimulus Immune Response-regulating Signaling Pathway Cellular Response To Stress Regulation Of Protein Phosphorylation Regulation Of Catalytic Activity Regulation Of Cellular Protein Metabolic Process Cellular Response To Growth Factor Stimulus Regulation Of Immune Response Response To Organic Cyclic Compound Regulation Of Signaling Transcription, DNA-templated Regulation Of Phosphorus Metabolic Process Gene Expression Regulation Of Cell Death Negative Regulation Of Cellular Metabolic Process RNA Biosynthetic Process Immune Response Regulation Of Phosphorylation Cell Differentiation Negative Regulation Of Signal Transduction Anatomical Structure Development Nitrogen Compound Metabolic Process Multicellular Organismal Development Defense Response Macromolecule Biosynthetic Process Biosynthetic Process RNA Metabolic Process Positive Regulation Of Gene Expression
Tagcloud ?		acetylation active binds chromatin compromising contributing disappearance erythroid explore expressions facilitating forming gata generation globin interestingly k562 knockdown locus looping near occupancy stabilizing stably structure tal1 though transcribing unclear	bovine casein catalytic cattle chromosome chromosomes coast composed conserved defined east encoding fever genomes homology hybrid mapped panel parasitic polymerase rodent segment somatic subunit subunits synteny theileriosis
Tagcloud (Difference) ?		acetylation active binds chromatin compromising contributing disappearance erythroid explore expressions facilitating forming gata generation globin interestingly k562 knockdown locus looping near occupancy stabilizing stably structure tal1 though transcribing unclear	bovine casein catalytic cattle chromosome chromosomes coast composed conserved defined east encoding fever genomes homology hybrid mapped panel parasitic polymerase rodent segment somatic subunit subunits synteny theileriosis
Tagcloud (Intersection) ?