CSNK2A2 and AQP4

Number of citations of the paper that reports this interaction (PMID 11742978)
29

Data Source:
HPRD (in vitro)

		CSNK2A2	AQP4
Gene Name		casein kinase 2, alpha prime polypeptide	aquaporin 4
Image
Gene Ontology Annotations	Cellular Component	Nucleus Cytosol PcG Protein Complex	Cytoplasm Plasma Membrane Integral Component Of Plasma Membrane Cell-cell Junction External Side Of Plasma Membrane Basolateral Plasma Membrane T-tubule Protein Complex
	Molecular Function	Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Protein N-terminus Binding	Water Transmembrane Transporter Activity Water Channel Activity Glycerol Channel Activity Porin Activity
	Biological Process	Mitotic Cell Cycle Transcription, DNA-templated Regulation Of Transcription, DNA-templated Protein Phosphorylation Apoptotic Process Axon Guidance Wnt Signaling Pathway Mitotic Spindle Checkpoint	Renal Water Homeostasis Transport Water Transport Female Pregnancy Sensory Perception Of Sound Response To Radiation Cellular Water Homeostasis Carbon Dioxide Transport Glycerol Transport Ion Transmembrane Transport Hyperosmotic Salinity Response Multicellular Organismal Water Homeostasis Protein Homooligomerization Response To Glucocorticoid Transmembrane Transport Renal Water Absorption Cellular Response To Interferon-gamma Cellular Response To Estradiol Stimulus
Pathways		Mitotic Prometaphase Signal transduction by L1 Axon guidance misspliced LRP5 mutants have enhanced beta-catenin-dependent signaling L1CAM interactions Signaling by Wnt Cell Cycle, Mitotic M Phase WNT mediated activation of DVL TCF dependent signaling in response to WNT RNF mutants show enhanced WNT signaling and proliferation XAV939 inhibits tankyrase, stabilizing AXIN Signaling by WNT in cancer Condensation of Prometaphase Chromosomes	Vasopressin regulates renal water homeostasis via Aquaporins Passive transport by Aquaporins Aquaporin-mediated transport
Drugs
Diseases
GWAS
Protein-Protein Interactions		92 interactors: ABCA1 ACACA ADH1A AQP4 ARR3 ARRB2 ASL ATF1 ATF2 BID CABP1 CALM1 CASQ2 CAV1 CDC37 CLTB CREBBP CREM CSN3 CSNK2B CTDP1 DCPS EEF1B2 EIF2B2 EIF2B5 EIF4EBP1 ERH FGF1 FGF2 FKBP3 FOS GTF2A1 GTF2A1L HDAC1 HDAC2 HDAC6 HIST1H1C HMGA1 HMGA2 HNRNPC HSP90AA1 HSP90B1 HSPH1 IL16 JUN KIF1C KLF1 LAMC3 LGALS3 MAF1 MAPK14 MGMT MS4A1 MYC MYCN MYF5 NAP1L4 NCL P4HB PAK1 PIN1 PIN4 PPP1R1B PPP1R2 PPP1R8 PRNP PTEN PTPN1 PTPRC RELA RGS19 SAT1 SLC18A2 SMURF1 SNCA SNX6 SPIB SPP1 STX1A TCF7L2 TCOF1 TGFBR1 TGM2 TOP1 TRIM41 TTLL12 UBE2R2 WAS XRCC1 ZNF219 ZNF670 ZNHIT3	4 interactors: AP2M1 AP3M1 CSNK2A1 CSNK2A2
Entrez ID		1459	361
HPRD ID		00279	02631
Ensembl ID		ENSG00000070770	ENSG00000171885
Uniprot IDs		P19784	F1DSG4 P55087
PDB IDs		3E3B 3OFM 3U87	3GD8
Enriched GO Terms of Interacting Partners?		Response To Organic Substance Regulation Of Metabolic Process Positive Regulation Of Cellular Metabolic Process Response To Stress Response To Abiotic Stimulus Response To Organonitrogen Compound Positive Regulation Of Metabolic Process Cellular Metabolic Process Positive Regulation Of Cellular Biosynthetic Process Cellular Response To Stimulus Regulation Of Gene Expression Developmental Process Innate Immune Response Cellular Response To Organic Substance Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Protein Metabolic Process Regulation Of Immune System Process Response To Growth Factor Enzyme Linked Receptor Protein Signaling Pathway Tissue Development Regulation Of Signal Transduction Regulation Of Nitrogen Compound Metabolic Process Response To Stimulus Immune Response-regulating Signaling Pathway Cellular Response To Stress Regulation Of Protein Phosphorylation Regulation Of Catalytic Activity Regulation Of Cellular Protein Metabolic Process Cellular Response To Growth Factor Stimulus Regulation Of Immune Response Response To Organic Cyclic Compound Regulation Of Signaling Transcription, DNA-templated Regulation Of Phosphorus Metabolic Process Gene Expression Regulation Of Cell Death Negative Regulation Of Cellular Metabolic Process RNA Biosynthetic Process Immune Response Regulation Of Phosphorylation Cell Differentiation Negative Regulation Of Signal Transduction Anatomical Structure Development Nitrogen Compound Metabolic Process Multicellular Organismal Development Defense Response Macromolecule Biosynthetic Process Biosynthetic Process RNA Metabolic Process Positive Regulation Of Gene Expression	Mitotic Spindle Checkpoint Movement Of Cell Or Subcellular Component Axon Guidance Negative Regulation Of Chromosome Segregation Spindle Checkpoint Regulation Of Mitotic Sister Chromatid Separation Negative Regulation Of Mitotic Nuclear Division Regulation Of Mitotic Metaphase/anaphase Transition Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Axonogenesis Negative Regulation Of Proteasomal Protein Catabolic Process Axon Development Negative Regulation Of Cellular Protein Catabolic Process Cell Morphogenesis Involved In Neuron Differentiation Chemotaxis Negative Regulation Of Cell Division Regulation Of Chromosome Segregation Neuron Projection Morphogenesis Negative Regulation Of Chromosome Organization Cell Morphogenesis Involved In Differentiation Negative Regulation Of Protein Catabolic Process Regulation Of Mitotic Nuclear Division Neuron Projection Development Cell Projection Morphogenesis Cell Part Morphogenesis Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Mitotic Cell Cycle Phase Transition Neuron Development Mitotic Cell Cycle Checkpoint Cell Morphogenesis Regulation Of Proteasomal Protein Catabolic Process Neuron Differentiation Regulation Of Chromosome Organization Cell Projection Organization Regulation Of Mitotic Cell Cycle Phase Transition Negative Regulation Of Mitotic Cell Cycle Regulation Of Cell Cycle Phase Transition Cell Cycle Checkpoint Locomotion Regulation Of Cell Division Wnt Signaling Pathway Generation Of Neurons Negative Regulation Of Proteolysis Neurogenesis Negative Regulation Of Protein Processing Regulation Of Protein Catabolic Process Regulation Of Protein Processing Cell Development Response To External Stimulus Regulation Of Mitotic Cell Cycle
Tagcloud ?		bovine casein catalytic cattle chromosome chromosomes coast composed conserved defined east encoding fever genomes homology hybrid mapped panel parasitic polymerase rodent segment somatic subunit subunits synteny theileriosis	3rds aquaporin blindness contiguous demyelinating edss gray holocord ig longitudinally malaysia monophasic myelitis neuritis neuromyelitis nmo nmosd optic optica paroxysmal relapses relapsing seronegative seropositive seropositivity spasms tonic transverse vertebral
Tagcloud (Difference) ?		bovine casein catalytic cattle chromosome chromosomes coast composed conserved defined east encoding fever genomes homology hybrid mapped panel parasitic polymerase rodent segment somatic subunit subunits synteny theileriosis	3rds aquaporin blindness contiguous demyelinating edss gray holocord ig longitudinally malaysia monophasic myelitis neuritis neuromyelitis nmo nmosd optic optica paroxysmal relapses relapsing seronegative seropositive seropositivity spasms tonic transverse vertebral
Tagcloud (Intersection) ?