MYL12A and SUV39H2

Number of citations of the paper that reports this interaction (PubMedID 23455924)
0

Data Source:
BioGRID (two hybrid)

		MYL12A	SUV39H2
Description		myosin light chain 12A	SUV39H2 histone lysine methyltransferase
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Myosin Complex Myosin II Complex Extracellular Exosome	Chromosome, Centromeric Region Chromatin Nucleus Nucleoplasm Chromosome
	Molecular Function	Calcium Ion Binding Protein Binding Myosin Heavy Chain Binding Metal Ion Binding	Transcription Cis-regulatory Region Binding Protein Binding Methyltransferase Activity Zinc Ion Binding Transferase Activity Histone Methyltransferase Activity Metal Ion Binding Histone H3K9 Methyltransferase Activity Histone H3 Methyltransferase Activity Histone H3K9 Trimethyltransferase Activity S-adenosyl-L-methionine Binding Ubiquitin-like Ligase-substrate Adaptor Activity
	Biological Process	Platelet Aggregation	Negative Regulation Of Transcription By RNA Polymerase II Chromatin Organization Chromatin Remodeling Circadian Rhythm Cell Differentiation Methylation Epigenetic Programming In The Zygotic Pronuclei Negative Regulation Of Gene Expression, Epigenetic Negative Regulation Of DNA-templated Transcription Rhythmic Process Cellular Response To Hypoxia
Pathways		Ephrin signaling Smooth Muscle Contraction	PKMTs methylate histone lysines
Drugs		4-[4-(2,5-DIOXO-PYRROLIDIN-1-YL)-PHENYLAMINO]-4-HYDROXY-BUTYRIC ACID
Diseases
GWAS		Night sleep phenotypes ( 27126917) QRS duration ( 27577874)	Response to cognitive-behavioural therapy in anxiety disorder ( 31123309)
Interacting Genes		6 interacting genes: CDKN2A FILNC1 GSK3A HSPB1 PTEN SUV39H2	43 interacting genes: AKAP9 APPL2 AR BLZF1 C8orf74 CBX7 CDCA4 CEP70 CFAP100 CGGBP1 EWSR1 FAM20C GOLGA6L9 GSTCD H3C1 ID2 KCTD17 KLF3 KLHDC4 LCA5L LNX1 LRIF1 MAGEA11 MCM3AP MRFAP1 MTF2 MYL12A NME4 ODAD3 PHF19 PNMA1 POLR3F RAB3IP RASSF1 SHC1 SMAD5 SNF8 UBE2V2 VHL WIZ ZNF212 ZNF557 ZNF57
Entrez ID		10627	79723
HPRD ID		14735	07580
Ensembl ID		ENSG00000101608	ENSG00000152455
Uniprot IDs		J3QRS3 P19105	Q9H5I1
PDB IDs			2R3A 6P0R
Enriched GO Terms of Interacting Partners?		Regulation Of Phosphorus Metabolic Process Regulation Of Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Phosphate Metabolic Process Regulation Of Protein Modification Process Negative Regulation Of Growth Regulation Of Cell-substrate Adhesion Epigenetic Programming Of Gene Expression Negative Regulation Of Organ Growth Negative Regulation Of Cell-matrix Adhesion Negative Regulation Of Cell Development Regulation Of Protein Targeting To Mitochondrion Negative Regulation Of Cell-substrate Adhesion Regulation Of Protein Phosphorylation Regulation Of Proteolysis Regulation Of Membrane Potential Regulation Of Phosphorylation Ligase Inhibitor Activity Negative Regulation Of UDP-glucose Catabolic Process Negative Regulation Of Protein Kinase C Signaling Negative Regulation Of Synaptic Vesicle Clustering Regulation Of Organ Growth Negative Regulation Of Developmental Growth Regulation Of Multicellular Organismal Development Negative Regulation Of Phosphorylation Negative Regulation Of Protein Phosphorylation Negative Regulation Of Type B Pancreatic Cell Development Positive Regulation Of Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Glycogen (starch) Synthase Activity Positive Regulation Of Adenylate Cyclase-activating Adrenergic Receptor Signaling Pathway Phosphatidylinositol-3,4-bisphosphate 3-phosphatase Activity Negative Regulation Of Keratinocyte Migration Inositol-1,3,4,5-tetrakisphosphate 3-phosphatase Activity Inositol-1,3,4,5,6-pentakisphosphate 3-phosphatase Activity Regulation Of Growth Regulation Of Protein Metabolic Process Regulation Of Cell-matrix Adhesion Positive Regulation Of Post-translational Protein Modification Circadian Rhythm Positive Regulation Of Proteolysis Involved In Protein Catabolic Process Positive Regulation Of Macrophage Apoptotic Process Apoptotic Process Involved In Mammary Gland Involution Protein Kinase C Inhibitor Activity Central Nervous System Myelin Maintenance Rhythmic Synaptic Transmission Negative Regulation Of Cell Differentiation Negative Regulation Of Cell Growth Negative Regulation Of Catalytic Activity Positive Regulation Of Apoptotic Process Involved In Mammary Gland Involution Regulation Of G1/S Transition Of Mitotic Cell Cycle Senescence-associated Heterochromatin Focus	Nucleoplasm Protein Binding Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Histone H3K36me3 Reader Activity Nucleus Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of RNA Metabolic Process RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding
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