MYL12A and SUV39H2

Number of citations of the paper that reports this interaction (PMID 23455924)
3

Data Source:
BioGRID (two hybrid)

		MYL12A	SUV39H2
Gene Name		myosin, light chain 12A, regulatory, non-sarcomeric	suppressor of variegation 3-9 homolog 2 (Drosophila)
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Stress Fiber Cytosol Myosin II Complex Z Disc Extracellular Vesicular Exosome	Chromosome, Centromeric Region Chromatin Nucleoplasm Nuclear Heterochromatin
	Molecular Function	Calcium Ion Binding Protein Binding Glutamate Receptor Binding	Transcription Regulatory Region Sequence-specific DNA Binding Chromatin Binding Protein Binding Zinc Ion Binding Histone Methyltransferase Activity (H3-K9 Specific)
	Biological Process	Axon Guidance Regulation Of Cell Shape Ephrin Receptor Signaling Pathway Platelet Aggregation Protein Targeting To Plasma Membrane	Negative Regulation Of Transcription From RNA Polymerase II Promoter Chromatin Organization Chromatin Assembly Or Disassembly Chromatin Remodeling Transcription, DNA-templated Male Meiosis Cell Differentiation Histone H3-K9 Dimethylation Histone H3-K9 Trimethylation Negative Regulation Of Circadian Rhythm Negative Regulation Of Transcription, DNA-templated Rhythmic Process Cellular Response To Hypoxia
Pathways		Ephrin signaling Axon guidance EPH-Ephrin signaling	Chromatin modifying enzymes Chromatin organization PKMTs methylate histone lysines
Drugs
Diseases
GWAS
Protein-Protein Interactions		2 interactors: CDKN2A SUV39H2	39 interactors: AKAP9 APPL2 BLZF1 C8orf74 CBX5 CBX7 CCDC151 CCDC37 CDCA4 CEP70 CGGBP1 EWSR1 FAM20C GSTCD ID2 KCTD17 KLF3 KLHDC4 LCA5L LNX1 LRIF1 MCM3AP MRFAP1 MTF2 MYL12A NME4 PHF19 PNMA1 POLR3F RAB3IP RASSF1 SHC1 SMAD5 SNF8 UBE2V2 WIZ ZNF212 ZNF557 ZNF57
Entrez ID		10627	79723
HPRD ID		14735	07580
Ensembl ID		ENSG00000101608	ENSG00000152455
Uniprot IDs		J3QRS3 P19105 Q53X45	Q9H5I1
PDB IDs			2R3A
Enriched GO Terms of Interacting Partners?		Chromatin Assembly Or Disassembly Chromatin Remodeling Senescence-associated Heterochromatin Focus Assembly Positive Regulation Of Cellular Senescence Histone H3-K9 Dimethylation Positive Regulation Of Smooth Muscle Cell Apoptotic Process Negative Regulation Of Immature T Cell Proliferation In Thymus Positive Regulation Of Macrophage Apoptotic Process Chromatin Modification Regulation Of Apoptotic DNA Fragmentation Positive Regulation Of Cell Aging Histone H3-K9 Trimethylation Peptidyl-lysine Dimethylation Positive Regulation Of Myeloid Cell Apoptotic Process Negative Regulation Of T Cell Differentiation In Thymus Chromatin Organization Heterochromatin Assembly Positive Regulation Of Protein Sumoylation Positive Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Regulation Of Smooth Muscle Cell Apoptotic Process Heterochromatin Organization Regulation Of Macrophage Apoptotic Process Replicative Senescence Positive Regulation Of Signal Transduction By P53 Class Mediator Negative Regulation Of B Cell Proliferation Negative Regulation Of Circadian Rhythm Regulation Of Protein Sumoylation Histone H3-K9 Methylation Chromosome Organization Protein Destabilization Regulation Of Execution Phase Of Apoptosis Regulation Of Cellular Senescence Peptidyl-lysine Trimethylation Negative Regulation Of Transcription, DNA-templated Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Somatic Stem Cell Division Negative Regulation Of RNA Biosynthetic Process Cellular Senescence Regulation Of Protein Export From Nucleus Regulation Of T Cell Differentiation In Thymus Positive Regulation Of Leukocyte Apoptotic Process Protein K63-linked Ubiquitination Histone H3-K9 Modification Negative Regulation Of T Cell Differentiation Negative Regulation Of Cell-matrix Adhesion Negative Regulation Of Gene Expression Negative Regulation Of B Cell Activation Regulation Of Myeloid Cell Apoptotic Process	Regulation Of Nitrogen Compound Metabolic Process Regulation Of Metabolic Process Transcription, DNA-templated RNA Biosynthetic Process Regulation Of Gene Expression Regulation Of Cellular Process Positive Regulation Of Histone H3-K27 Methylation Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Histone H3-K27 Methylation Regulation Of RNA Metabolic Process Gene Expression Nucleobase-containing Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process RNA Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Osteoblast Differentiation Biosynthetic Process Regulation Of Epidermal Growth Factor-activated Receptor Activity Golgi To Plasma Membrane Transport Positive Regulation Of Histone Methylation Nitrogen Compound Metabolic Process Positive Regulation Of DNA Metabolic Process Osteoclast Maturation Regulation Of Histone Methylation Regulation Of Ossification Protein Targeting Positive Regulation Of Transcription Involved In G1/S Transition Of Mitotic Cell Cycle Negative Regulation Of Transcription, DNA-templated Regulation Of Protein Tyrosine Kinase Activity Positive Regulation Of Cellular Protein Metabolic Process Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of RNA Biosynthetic Process Establishment Of Protein Localization To Membrane Positive Regulation Of DNA Replication Positive Regulation Of Histone Modification Protein Targeting To Vacuole Involved In Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Positive Regulation Of Osteoblast Differentiation Myeloid Cell Differentiation Negative Regulation Of Gene Expression, Epigenetic Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Establishment Of Protein Localization To Plasma Membrane Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition
Tagcloud ?			a7 circular dichroism dim g12 g13 g9a h3k9 h3k9me0 h3k9me1 h3k9me2 h3k9me3 introduce introduces k14 labrador n324k pkmts prefers processive r8 readout recognizes renders retrievers s10 t11 t6
Tagcloud (Difference) ?			a7 circular dichroism dim g12 g13 g9a h3k9 h3k9me0 h3k9me1 h3k9me2 h3k9me3 introduce introduces k14 labrador n324k pkmts prefers processive r8 readout recognizes renders retrievers s10 t11 t6
Tagcloud (Intersection) ?