PRPF8 and SND1

Number of citations of the paper that reports this interaction (PMID 17632523)
22

Data Source:
BioGRID (pull down)

		PRPF8	SND1
Gene Name		pre-mRNA processing factor 8	staphylococcal nuclease and tudor domain containing 1
Image
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm U5 SnRNP Membrane Nuclear Speck Catalytic Step 2 Spliceosome	Nucleus Cytoplasm Mitochondrion Membrane RISC Complex Melanosome Extracellular Vesicular Exosome Dense Body
	Molecular Function	Protein Binding U6 SnRNA Binding U5 SnRNA Binding Poly(A) RNA Binding K63-linked Polyubiquitin Binding	Transcription Cofactor Activity Nuclease Activity Protein Binding Poly(A) RNA Binding
	Biological Process	Spliceosomal Tri-snRNP Complex Assembly RNA Splicing, Via Transesterification Reactions MRNA Splicing, Via Spliceosome MRNA Processing RNA Splicing Gene Expression	Osteoblast Differentiation Transcription, DNA-templated Regulation Of Transcription, DNA-templated Viral Process Gene Silencing By RNA Nucleic Acid Phosphodiester Bond Hydrolysis
Pathways		Processing of Capped Intron-Containing Pre-mRNA mRNA Splicing mRNA Splicing - Minor Pathway mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS		Calcium levels ( 20705733)	Type 2 diabetes ( 23532257)
Protein-Protein Interactions		14 interactors: ABCA1 DHX9 EFTUD2 ERG GPKOW HNRNPH2 NEDD4 PIN1 PRPF19 SERPINB2 SND1 SNRNP200 UBC ZNF830	19 interactors: APP CREBBP CSNK2A1 GTF2E1 GTF2E2 LZTR1 MAK MYB MYBL2 PIM1 POLR2A PRPF8 RBPJ RNU1-1 RNU2-1 RNU4-1 RNU5A-1 RNU6-1 STAT6
Entrez ID		10594	27044
HPRD ID		06295	03714
Ensembl ID		ENSG00000174231	ENSG00000197157
Uniprot IDs		Q6P2Q9	Q7KZF4
PDB IDs		3E9L 3ENB 3LRU 4JK7 4JK8 4JK9 4JKA 4JKB 4JKC 4JKD 4JKE 4JKF 4JKG 4JKH 4KIT	2E6N 2HQE 2HQX 2O4X 3BDL 3OMC 3OMG
Enriched GO Terms of Interacting Partners?		MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions RNA Splicing MRNA Processing MRNA Metabolic Process RNA Processing Regulation Of Type I Interferon Production Negative Regulation Of Cellular Response To Growth Factor Stimulus Osteoblast Differentiation DNA Damage Checkpoint Blastocyst Growth Protein Polyubiquitination RNA Metabolic Process Regulation Of Cellular Response To Growth Factor Stimulus Protein K63-linked Ubiquitination Regulation Of Potassium Ion Transmembrane Transport Response To Stress Gene Expression Nucleobase-containing Compound Metabolic Process Cell Cycle Checkpoint Negative Regulation Of Type I Interferon Production Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Regulation Of DNA-templated Transcription In Response To Stress Ossification Cellular Nitrogen Compound Metabolic Process Signal Transduction Involved In DNA Damage Checkpoint Signal Transduction Involved In Cell Cycle Checkpoint Regulation Of Potassium Ion Transport Spliceosomal Complex Assembly Negative Regulation Of Transcription From RNA Polymerase II Promoter In Response To UV-induced DNA Damage Generation Of Catalytic Spliceosome For First Transesterification Step Negative Regulation Of Potassium Ion Export Transmission Of Virus Development Involved In Symbiotic Interaction Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Positive Regulation Of Ubiquitin-protein Transferase Activity Positive Regulation Of Ligase Activity Positive Regulation Of Type I Interferon Production Nitrogen Compound Metabolic Process Cis Assembly Of Pre-catalytic Spliceosome Regulation Of Heart Rate By Hormone Cellular Metabolic Process Regulation Of Ubiquitin-protein Transferase Activity Cellular Response To Stress Signal Transduction In Response To DNA Damage Mitotic DNA Damage Checkpoint Negative Regulation Of Ion Transport Regulation Of Mitotic Cell Cycle	Regulation Of Transcription, DNA-templated RNA Metabolic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Gene Expression Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Transcription Initiation From RNA Polymerase II Promoter Transcription, DNA-templated Nitrogen Compound Metabolic Process RNA Biosynthetic Process DNA-templated Transcription, Initiation Nucleobase-containing Compound Metabolic Process Transcription From RNA Polymerase II Promoter Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Regulation Of Metabolic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Transcription Elongation From RNA Polymerase II Promoter Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Cellular Biosynthetic Process DNA-templated Transcription, Elongation Positive Regulation Of Metabolic Process Positive Regulation Of Cellular Metabolic Process Biosynthetic Process Positive Regulation Of Transcription, DNA-templated Notch Signaling Pathway Stem Cell Maintenance Regulation Of Cell Cycle Cellular Metabolic Process Developmental Process Cell Differentiation Viral Process Lymphocyte Differentiation Regulation Of Transcription From RNA Polymerase II Promoter Stem Cell Development Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Anatomical Structure Development Cell Activation Mitotic Cell Cycle Process Positive Regulation Of Canonical Wnt Signaling Pathway Involved In Cardiac Muscle Cell Fate Commitment Positive Regulation Of Ephrin Receptor Signaling Pathway Arterial Endothelial Cell Fate Commitment Epidermal Cell Fate Specification
Tagcloud ?		abcb7 advance alas2 asxl1 bclaf1 brca1 causal cbl cd34 december deregulation disruption doi erythroid exon hnrnpd leu link online pathophysiology publication rars refractory sf3b1 sideroblasts slc25a37 splicing transcript transcriptome	analyzing approached atf6 ectopic endoplasmic flanking fragment glycosylation hepatoma inducers maximal maximally modulated near nuclease numerous pharmacological promoter protection proximal question reticulum staphyloccocal stresses thapsigargin triggered tunicamycin unfolded upregulated
Tagcloud (Difference) ?		abcb7 advance alas2 asxl1 bclaf1 brca1 causal cbl cd34 december deregulation disruption doi erythroid exon hnrnpd leu link online pathophysiology publication rars refractory sf3b1 sideroblasts slc25a37 splicing transcript transcriptome	analyzing approached atf6 ectopic endoplasmic flanking fragment glycosylation hepatoma inducers maximal maximally modulated near nuclease numerous pharmacological promoter protection proximal question reticulum staphyloccocal stresses thapsigargin triggered tunicamycin unfolded upregulated
Tagcloud (Intersection) ?