SND1 and GTF2E1

Number of citations of the paper that reports this interaction (PMID 7651391)
66

Data Source:
HPRD (in vitro, in vivo)

		SND1	GTF2E1
Gene Name		staphylococcal nuclease and tudor domain containing 1	general transcription factor IIE, polypeptide 1, alpha 56kDa
Image
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Mitochondrion Membrane RISC Complex Melanosome Extracellular Vesicular Exosome Dense Body	Nucleoplasm Intermediate Filament Cytoskeleton
	Molecular Function	Transcription Cofactor Activity Nuclease Activity Protein Binding Poly(A) RNA Binding	Protein Binding Sequence-specific DNA Binding Metal Ion Binding
	Biological Process	Osteoblast Differentiation Transcription, DNA-templated Regulation Of Transcription, DNA-templated Viral Process Gene Silencing By RNA Nucleic Acid Phosphodiester Bond Hydrolysis	Regulation Of Transcription, DNA-templated Transcription From RNA Polymerase II Promoter Transcription Initiation From RNA Polymerase II Promoter Transcription Elongation From RNA Polymerase II Promoter Gene Expression Viral Process
Pathways			RNA Polymerase II Promoter Escape RNA Polymerase II Transcription Pre-Initiation And Promoter Opening RNA Polymerase II Transcription HIV Infection RNA Polymerase II Pre-transcription Events Late Phase of HIV Life Cycle HIV Life Cycle HIV Transcription Initiation RNA Polymerase II Transcription Initiation And Promoter Clearance RNA Polymerase II HIV Promoter Escape RNA Polymerase II Transcription Initiation Transcription of the HIV genome
Drugs
Diseases
GWAS		Type 2 diabetes ( 23532257)	Obesity-related traits ( 23251661)
Protein-Protein Interactions		19 interactors: APP CREBBP CSNK2A1 GTF2E1 GTF2E2 LZTR1 MAK MYB MYBL2 PIM1 POLR2A PRPF8 RBPJ RNU1-1 RNU2-1 RNU4-1 RNU5A-1 RNU6-1 STAT6	28 interactors: AES APP CBFA2T2 CDK7 ERCC3 GTF2A1 GTF2A2 GTF2B GTF2E2 GTF2F2 GTF2H1 GTF2H4 IKBKG MDM2 PCBD2 POLR2A SND1 SRPK2 TAF1 TAF11 TAF6 TBP TCEA1 TRIM15 TRIM24 TRIM29 ZBTB9 ZSCAN1
Entrez ID		27044	2960
HPRD ID		03714	01799
Ensembl ID		ENSG00000197157	ENSG00000153767
Uniprot IDs		Q7KZF4	P29083
PDB IDs		2E6N 2HQE 2HQX 2O4X 3BDL 3OMC 3OMG	1VD4 2JTX 2RNQ 2RNR
Enriched GO Terms of Interacting Partners?		Regulation Of Transcription, DNA-templated RNA Metabolic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Gene Expression Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Transcription Initiation From RNA Polymerase II Promoter Transcription, DNA-templated Nitrogen Compound Metabolic Process RNA Biosynthetic Process DNA-templated Transcription, Initiation Nucleobase-containing Compound Metabolic Process Transcription From RNA Polymerase II Promoter Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Regulation Of Metabolic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Transcription Elongation From RNA Polymerase II Promoter Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Cellular Biosynthetic Process DNA-templated Transcription, Elongation Positive Regulation Of Metabolic Process Positive Regulation Of Cellular Metabolic Process Biosynthetic Process Positive Regulation Of Transcription, DNA-templated Notch Signaling Pathway Stem Cell Maintenance Regulation Of Cell Cycle Cellular Metabolic Process Developmental Process Cell Differentiation Viral Process Lymphocyte Differentiation Regulation Of Transcription From RNA Polymerase II Promoter Stem Cell Development Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Anatomical Structure Development Cell Activation Mitotic Cell Cycle Process Positive Regulation Of Canonical Wnt Signaling Pathway Involved In Cardiac Muscle Cell Fate Commitment Positive Regulation Of Ephrin Receptor Signaling Pathway Arterial Endothelial Cell Fate Commitment Epidermal Cell Fate Specification	Transcription Elongation From RNA Polymerase II Promoter DNA-templated Transcription, Elongation Transcription Initiation From RNA Polymerase II Promoter Viral Process DNA-templated Transcription, Initiation Regulation Of RNA Metabolic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Transcription From RNA Polymerase II Promoter Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Transcription, DNA-templated RNA Metabolic Process RNA Biosynthetic Process Gene Expression Positive Regulation Of Viral Process Positive Regulation Of Viral Transcription Regulation Of Viral Process Positive Regulation Of Gene Expression Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Metabolic Process Regulation Of Viral Transcription Cellular Nitrogen Compound Metabolic Process Nucleobase-containing Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Nitrogen Compound Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process 7-methylguanosine MRNA Capping Positive Regulation Of Cellular Biosynthetic Process 7-methylguanosine RNA Capping Biosynthetic Process Transcription-coupled Nucleotide-excision Repair Termination Of RNA Polymerase I Transcription Transcription Elongation From RNA Polymerase I Promoter Transcription Initiation From RNA Polymerase I Promoter Positive Regulation Of Cellular Metabolic Process Transcription From RNA Polymerase I Promoter Nucleotide-excision Repair Positive Regulation Of Metabolic Process Regulation Of Cellular Process Nucleotide-excision Repair, DNA Damage Removal Positive Regulation Of Transcription, DNA-templated MRNA Processing DNA-templated Transcription, Termination Negative Regulation Of Gene Expression, Epigenetic Cellular Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter
Tagcloud ?		analyzing approached atf6 ectopic endoplasmic flanking fragment glycosylation hepatoma inducers maximal maximally modulated near nuclease numerous pharmacological promoter protection proximal question reticulum staphyloccocal stresses thapsigargin triggered tunicamycin unfolded upregulated	avenues bioinformatics bl canonical conferring dhx8 disrupted dnaja1 galactosidase hap1 insertional kalrn lytic mechanistic mutagenesis participate queried replication screens share tat throughput tzm uba3 ube2e3 utilizing viable vmp1
Tagcloud (Difference) ?		analyzing approached atf6 ectopic endoplasmic flanking fragment glycosylation hepatoma inducers maximal maximally modulated near nuclease numerous pharmacological promoter protection proximal question reticulum staphyloccocal stresses thapsigargin triggered tunicamycin unfolded upregulated	avenues bioinformatics bl canonical conferring dhx8 disrupted dnaja1 galactosidase hap1 insertional kalrn lytic mechanistic mutagenesis participate queried replication screens share tat throughput tzm uba3 ube2e3 utilizing viable vmp1
Tagcloud (Intersection) ?