SCGN and SNAP23

Number of citations of the paper that reports this interaction (PMID 16189514)
699

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		SCGN	SNAP23
Gene Name		secretagogin, EF-hand calcium binding protein	synaptosomal-associated protein, 23kDa
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Region Cytoplasm Transport Vesicle Membrane	Nucleoplasm Cytoplasm Plasma Membrane Focal Adhesion SNARE Complex Specific Granule Azurophil Granule Mast Cell Granule Neuron Projection Synapse Extracellular Vesicular Exosome
	Molecular Function	Calcium Ion Binding	SNAP Receptor Activity Protein Binding Syntaxin Binding
	Biological Process	Biological_process	Histamine Secretion By Mast Cell Post-Golgi Vesicle-mediated Transport Vesicle Targeting Protein Transport Synaptic Vesicle Priming Synaptic Vesicle Fusion To Presynaptic Membrane Membrane Organization Membrane Fusion
Pathways			Translocation of GLUT4 to the plasma membrane trans-Golgi Network Vesicle Budding Clathrin derived vesicle budding
Drugs
Diseases
GWAS		Iron status biomarkers ( 19084217) Uric acid levels ( 19503597)
Protein-Protein Interactions		1 interactors: SNAP23	34 interactors: ABI2 ABI3 CFTR FXR2 ITSN1 KIF5B MATR3 NAPA NAPB PRKCA SCAMP1 SCAMP2 SCGN SNAPIN SNTG1 STX11 STX12 STX1A STX1B STX2 STX3 STX4 STX5 STX6 STXBP2 STXBP5 TLK1 VAMP1 VAMP2 VAMP3 VAMP5 VAMP7 VAMP8 WASH2P
Entrez ID		10590	8773
HPRD ID		10211	03962
Ensembl ID		ENSG00000079689	ENSG00000092531
Uniprot IDs		O76038	A8K287 O00161
PDB IDs			1NHL 3ZUS
Enriched GO Terms of Interacting Partners?		Synaptic Vesicle Priming Synaptic Vesicle Fusion To Presynaptic Membrane Histamine Secretion By Mast Cell Histamine Secretion Histamine Transport Mast Cell Degranulation Production Of Molecular Mediator Involved In Inflammatory Response Mast Cell Mediated Immunity Lysosome Localization Mast Cell Activation Vesicle Targeting Leukocyte Degranulation Vesicle Fusion Regulated Secretory Pathway Synaptic Vesicle Exocytosis Ammonium Transport Organelle Fusion Hormone Secretion Post-Golgi Vesicle-mediated Transport Hormone Transport Neurotransmitter Secretion Synaptic Vesicle Transport Membrane Fusion Regulation Of Neurotransmitter Levels Leukocyte Activation Involved In Immune Response Neurotransmitter Transport Establishment Of Vesicle Localization Vesicle Organization Vesicle Localization Inorganic Anion Transport Regulation Of Hormone Levels Golgi Vesicle Transport Leukocyte Mediated Immunity Establishment Of Organelle Localization Exocytosis Cellular Protein Complex Assembly Organelle Localization Inflammatory Response Leukocyte Activation Secretion By Cell Synaptic Transmission Secretion Cellular Macromolecular Complex Assembly Monovalent Inorganic Cation Transport Anion Transport Cell Activation	Vesicle Fusion Membrane Fusion Organelle Fusion Vesicle Organization Vesicle-mediated Transport Establishment Of Localization In Cell Exocytosis Cellular Localization Protein Transport Membrane Organization Establishment Of Protein Localization Intracellular Transport Secretion By Cell Synaptic Vesicle Fusion To Presynaptic Membrane Vesicle Docking Membrane Docking Secretion Protein Localization Neurotransmitter Secretion Intracellular Protein Transport Post-Golgi Vesicle-mediated Transport Regulation Of Neurotransmitter Levels Synaptic Vesicle Exocytosis Neurotransmitter Transport Synaptic Vesicle Transport Golgi Vesicle Transport Transport Establishment Of Vesicle Localization Vesicle Localization Cellular Protein Localization SNARE Complex Assembly Regulation Of Exocytosis Establishment Of Organelle Localization Organelle Organization Regulation Of Cellular Localization Cell-cell Signaling Organelle Localization Synaptic Transmission Regulation Of Secretion Regulation Of Vesicle-mediated Transport Calcium Ion-dependent Exocytosis Positive Regulation Of Synaptic Transmission Regulation Of Synaptic Vesicle Priming Positive Regulation Of Exocytosis Golgi To Plasma Membrane Protein Transport Positive Regulation Of Transport Neutrophil Degranulation Regulation Of Cellular Component Organization Golgi To Plasma Membrane Transport Regulation Of Synaptic Transmission
Tagcloud ?		abcg2 cumulative dementia gckr grs hoehn lrrc16a participant pd pdzk1 rs1183201 rs12129861 rs12356193 rs17300741 rs2231142 rs505802 rs734553 rs742132 rs780094 slc16a9 slc17a1 slc22a11 slc22a12 slc2a9 taqman ua updrs uric yahr	apical brevin brevins cellubrevin clostridial codistributed cryosections exocytosis exocytotic immunogold insensitive maleimide nem neurotoxin neurotoxins nsf nts proteolyze snare snares syntaxin tent tetanus ti ultrathin vamp vesicle
Tagcloud (Difference) ?		abcg2 cumulative dementia gckr grs hoehn lrrc16a participant pd pdzk1 rs1183201 rs12129861 rs12356193 rs17300741 rs2231142 rs505802 rs734553 rs742132 rs780094 slc16a9 slc17a1 slc22a11 slc22a12 slc2a9 taqman ua updrs uric yahr	apical brevin brevins cellubrevin clostridial codistributed cryosections exocytosis exocytotic immunogold insensitive maleimide nem neurotoxin neurotoxins nsf nts proteolyze snare snares syntaxin tent tetanus ti ultrathin vamp vesicle
Tagcloud (Intersection) ?