SCGN and ATP5F1A

Number of citations of the paper that reports this interaction (PubMedID 21528130)
0

Data Source:
BioGRID (pull down)

		SCGN	ATP5F1A
Description		secretagogin, EF-hand calcium binding protein	ATP synthase F1 subunit alpha
Image
GO Annotations	Cellular Component	Extracellular Region Nucleus Cytoplasm Cytosol Membrane Dendrite Transport Vesicle Membrane Cytoplasmic Vesicle Terminal Bouton Synapse	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Matrix Plasma Membrane Cell Surface Membrane Proton-transporting Two-sector ATPase Complex Membrane Raft Proton-transporting ATP Synthase Complex Extracellular Exosome Transmembrane Transporter Complex
	Molecular Function	Calcium Ion Binding Protein Binding Metal Ion Binding	Nucleotide Binding Protease Binding RNA Binding Protein Binding ATP Binding ATP Hydrolysis Activity Adenyl Ribonucleotide Binding MHC Class I Protein Binding ADP Binding Angiostatin Binding Proton-transporting ATP Synthase Activity, Rotational Mechanism
	Biological Process		Negative Regulation Of Endothelial Cell Proliferation Lipid Metabolic Process ATP Biosynthetic Process Monoatomic Ion Transport Response To Muscle Activity Proton Motive Force-driven ATP Synthesis Proton Motive Force-driven Mitochondrial ATP Synthesis Positive Regulation Of Blood Vessel Endothelial Cell Migration Response To Ethanol ATP Metabolic Process Cellular Response To Dexamethasone Stimulus Cellular Response To Nitric Oxide Proton Transmembrane Transport
Pathways			Mitochondrial protein import Formation of ATP by chemiosmotic coupling Cristae formation Mitochondrial protein degradation
Drugs			Quercetin 1-ACETYL-2-CARBOXYPIPERIDINE AUROVERTIN B Piceatannol N1-(2-AMINO-4-METHYLPENTYL)OCTAHYDRO-PYRROLO[1,2-A] PYRIMIDINE Artenimol
Diseases
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Brain morphology (MOSTest) ( 32665545) Feeling guilty ( 29500382) Fish- and plant-related diet ( 32066663) HDL cholesterol levels ( 32203549) Intrinsic epigenetic age acceleration ( 29374233) Iron status biomarkers ( 19084217) Iron status biomarkers (iron levels) ( 28334935) Iron status biomarkers (total iron binding capacity) ( 28334935) Iron status biomarkers (transferrin saturation) ( 28334935) Liver iron content ( 34128465) Lung cancer in ever smokers ( 28604730) Oily fish consumption ( 32066663) Peak cortisol response to low dose short synacthen test in corticosteroid treated asthma ( 29551627) Plateletcrit ( 32888494) Pork consumption ( 32066663) Refractive error ( 32231278) Squamous cell lung carcinoma ( 28604730) Subcortical volume (MOSTest) ( 32665545) Total cholesterol change in response to fenofibrate in statin-treated type 2 diabetes ( 28736931) Uric acid levels ( 19503597) Waist circumference adjusted for body mass index ( 34021172)
Interacting Genes		7 interacting genes: ARFGAP2 ATP5F1A DDAH2 KIF5B MLF2 SNAP23 TUBB3	24 interacting genes: ABCC1 AIMP1 AIRE APP ATP5F1C ATPAF2 CSNK2A1 FNDC3B HSD17B10 HSPB2 LINC00941 LINC01554 NPSR1 OGT PTEN PTPRF SCGN SHBG SMARCB1 TNK2 YWHAB YWHAG YWHAQ YWHAZ
Entrez ID		10590	498
HPRD ID		10211	01258
Ensembl ID		ENSG00000079689	ENSG00000152234
Uniprot IDs		O76038	P25705 V9HW26
PDB IDs		8BAV	8H9E 8H9I 8H9L 8H9P 8H9S 8H9T 8H9U 8H9V 8KI3
Enriched GO Terms of Interacting Partners?		Mitochondrion Adenyl Ribonucleotide Binding Proton-transporting Two-sector ATPase Complex Angiostatin Binding Stress Granule Disassembly Anterograde Neuronal Dense Core Vesicle Transport Ciliary Rootlet Plus-end-directed Vesicle Transport Along Microtubule Anterograde Dendritic Transport Of Neurotransmitter Receptor Complex Cytoplasm Organization Neuron Projection Guidance Cytolytic Granule Membrane Retrograde Neuronal Dense Core Vesicle Transport Anterograde Axonal Protein Transport Regulation Of Modification Of Synapse Structure, Modulating Synaptic Transmission Axon Guidance Plus-end-directed Organelle Transport Along Microtubule Mitocytosis Dense Core Granule Cytoskeletal Transport Histamine Secretion By Mast Cell Histamine Transport Histamine Secretion Netrin-activated Signaling Pathway Netrin Receptor Binding Dorsal Root Ganglion Development Citrulline Metabolic Process Dimethylargininase Activity COPI Coating Of Golgi Vesicle Synaptic Vesicle Fusion To Presynaptic Active Zone Membrane Anterograde Dendritic Transport Azurophil Granule Vesicle Fusion To Plasma Membrane	Negative Regulation Of Protein Localization To Nucleus Protein Targeting Negative Regulation Of Translational Initiation Phosphoserine Residue Binding Protein Sequestering Activity Identical Protein Binding TORC1 Signaling Regulation Of Translation Protein Domain Specific Binding TOR Signaling Protein Localization To Vacuole Positive Regulation Of Cell Communication Positive Regulation Of Signaling Regulation Of Translational Initiation Sin3-type Complex Regulation Of TORC1 Signaling Post-transcriptional Regulation Of Gene Expression Central Tolerance Induction To Self Antigen Peripheral T Cell Tolerance Induction Positive Regulation Of Transcription By RNA Polymerase II Amyloid-beta Complex Regulation Of Phosphorus Metabolic Process Growth Cone Lamellipodium Positive Regulation Of Protein Metabolic Process Regulation Of Response To Calcium Ion Positive Regulation Of Excitatory Postsynaptic Potential Amylin Binding Positive Regulation Of Toll Signaling Pathway Regulation Of Protein Localization To Nucleus Positive Regulation Of Signal Transduction Reproductive Behavior Isoursodeoxycholate 7-beta-dehydrogenase (NAD+) Activity Chenodeoxycholate 7-alpha-dehydrogenase (NAD+) Activity 3-hydroxy-2-methylbutyryl-CoA Dehydrogenase Activity Cholate 7-alpha-dehydrogenase (NAD+) Activity Ursodeoxycholate 7-beta-dehydrogenase (NAD+) Activity Negative Regulation Of Synaptic Vesicle Clustering Chondroitin Sulfate Proteoglycan Binding Single Stranded Viral RNA Replication Via Double Stranded DNA Intermediate Regulation Of TOR Signaling Protein N-acetylglucosaminyltransferase Complex Negative Regulation Of Non-canonical Inflammasome Complex Assembly Positive Regulation Of Glucagon Secretion Negative Regulation Of Defecation Synapse
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