SCGN and ARFGAP2

Number of citations of the paper that reports this interaction (PubMedID 21528130)
0

Data Source:
BioGRID (pull down)

		SCGN	ARFGAP2
Description		secretagogin, EF-hand calcium binding protein	ARF GTPase activating protein 2
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GO Annotations	Cellular Component	Extracellular Region Nucleus Cytoplasm Cytosol Membrane Dendrite Transport Vesicle Membrane Cytoplasmic Vesicle Terminal Bouton Synapse	Golgi Membrane Cytoplasm Golgi Apparatus Cytosol Plasma Membrane Membrane
	Molecular Function	Calcium Ion Binding Protein Binding Metal Ion Binding	GTPase Activator Activity Zinc Ion Binding Metal Ion Binding
	Biological Process		Protein Transport Vesicle-mediated Transport COPI Coating Of Golgi Vesicle
Pathways			COPI-mediated anterograde transport COPI-dependent Golgi-to-ER retrograde traffic CDC42 GTPase cycle
Drugs
Diseases
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Brain morphology (MOSTest) ( 32665545) Feeling guilty ( 29500382) Fish- and plant-related diet ( 32066663) HDL cholesterol levels ( 32203549) Intrinsic epigenetic age acceleration ( 29374233) Iron status biomarkers ( 19084217) Iron status biomarkers (iron levels) ( 28334935) Iron status biomarkers (total iron binding capacity) ( 28334935) Iron status biomarkers (transferrin saturation) ( 28334935) Liver iron content ( 34128465) Lung cancer in ever smokers ( 28604730) Oily fish consumption ( 32066663) Peak cortisol response to low dose short synacthen test in corticosteroid treated asthma ( 29551627) Plateletcrit ( 32888494) Pork consumption ( 32066663) Refractive error ( 32231278) Squamous cell lung carcinoma ( 28604730) Subcortical volume (MOSTest) ( 32665545) Total cholesterol change in response to fenofibrate in statin-treated type 2 diabetes ( 28736931) Uric acid levels ( 19503597) Waist circumference adjusted for body mass index ( 34021172)	Alzheimer's disease or fasting glucose levels (pleiotropy) ( 30805717) Autism spectrum disorder or schizophrenia ( 28540026) General factor of neuroticism ( 30867560)
Interacting Genes		7 interacting genes: ARFGAP2 ATP5F1A DDAH2 KIF5B MLF2 SNAP23 TUBB3	2 interacting genes: SCGN SNCA
Entrez ID		10590	84364
HPRD ID		10211	06069
Ensembl ID		ENSG00000079689	ENSG00000149182
Uniprot IDs		O76038	E9PN48 G5E9L0 Q8N6H7
PDB IDs		8BAV	2P57
Enriched GO Terms of Interacting Partners?		Mitochondrion Adenyl Ribonucleotide Binding Proton-transporting Two-sector ATPase Complex Angiostatin Binding Stress Granule Disassembly Anterograde Neuronal Dense Core Vesicle Transport Ciliary Rootlet Plus-end-directed Vesicle Transport Along Microtubule Anterograde Dendritic Transport Of Neurotransmitter Receptor Complex Cytoplasm Organization Neuron Projection Guidance Cytolytic Granule Membrane Retrograde Neuronal Dense Core Vesicle Transport Anterograde Axonal Protein Transport Regulation Of Modification Of Synapse Structure, Modulating Synaptic Transmission Axon Guidance Plus-end-directed Organelle Transport Along Microtubule Mitocytosis Dense Core Granule Cytoskeletal Transport Histamine Secretion By Mast Cell Histamine Transport Histamine Secretion Netrin-activated Signaling Pathway Netrin Receptor Binding Dorsal Root Ganglion Development Citrulline Metabolic Process Dimethylargininase Activity COPI Coating Of Golgi Vesicle Synaptic Vesicle Fusion To Presynaptic Active Zone Membrane Anterograde Dendritic Transport Azurophil Granule Vesicle Fusion To Plasma Membrane	Terminal Bouton Response To Desipramine Response To Interleukin-1 Negative Regulation Of Norepinephrine Uptake Phospholipase D Inhibitor Activity Positive Regulation Of SNARE Complex Assembly Negative Regulation Of Dopamine Uptake Involved In Synaptic Transmission Myeloid Leukocyte Activation Regulation Of Protein Localization To Cell Periphery Regulation Of Norepinephrine Uptake Cell Cortex Negative Regulation Of Mitochondrial Electron Transport, NADH To Ubiquinone Positive Regulation Of Hydrogen Peroxide Catabolic Process Negative Regulation Of Serotonin Uptake Transporter Regulator Activity Negative Regulation Of Chaperone-mediated Autophagy Negative Regulation Of Dopamine Metabolic Process Regulation Of Serotonin Uptake Positive Regulation Of Phosphate Metabolic Process Negative Regulation Of Thrombin-activated Receptor Signaling Pathway Dopamine Uptake Involved In Synaptic Transmission Negative Regulation Of Catecholamine Metabolic Process Response To Lipopolysaccharide Interleukin-17A-mediated Signaling Pathway Response To Molecule Of Bacterial Origin Mitochondrial ATP Synthesis Coupled Electron Transport Cuprous Ion Binding Regulation Of Chaperone-mediated Autophagy Enzyme Binding Catecholamine Uptake Dopamine Uptake Response To Iron(II) Ion Dopamine Biosynthetic Process Regulation Of Dopamine Uptake Involved In Synaptic Transmission Regulation Of Acyl-CoA Biosynthetic Process Positive Regulation Of Inositol Phosphate Biosynthetic Process Negative Regulation Of Cellular Respiration Supramolecular Fiber Negative Regulation Of Oxidative Phosphorylation CD40 Signaling Pathway Positive Regulation Of Lipopolysaccharide-mediated Signaling Pathway CD40 Receptor Complex TRIF-dependent Toll-like Receptor Signaling Pathway Protein Kinase B Binding Interleukin-33-mediated Signaling Pathway T-helper 1 Type Immune Response Interleukin-17-mediated Signaling Pathway Positive Regulation Of Neurotransmitter Secretion Regulation Of SNARE Complex Assembly Regulation Of Hydrogen Peroxide Metabolic Process
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