AKAP3 and ROPN1

Number of citations of the paper that reports this interaction (PubMedID 11278869)
0

Data Source:
HPRD (two hybrid, in vitro)

		AKAP3	ROPN1
Description		A-kinase anchoring protein 3	rhophilin associated tail protein 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Acrosomal Vesicle Nucleus Cytoplasm Cilium Cytoplasmic Vesicle Motile Cilium Sperm Fibrous Sheath Cell Projection Sperm Midpiece Sperm Principal Piece	Nucleus Cytoplasm Cilium Motile Cilium Cell Projection
	Molecular Function	Protein Binding Protein Kinase A Binding	Protein Binding Identical Protein Binding
	Biological Process	Blastocyst Hatching Cell Surface Receptor Protein Serine/threonine Kinase Signaling Pathway Single Fertilization Acrosome Reaction Intracellular Protein Localization Flagellated Sperm Motility Establishment Of Protein Localization	Flagellated Sperm Motility Cilium Organization Sperm Capacitation Protein Localization To Cilium
Pathways			RHO GTPases Activate Rhotekin and Rhophilins
Drugs
Diseases
GWAS		Gut microbiota (bacterial taxa) ( 27723756)	Benign childhood epilepsy with centro-temporal spikes ( 32580138) Household income ( 31844048) Household income (MTAG) ( 31844048)
Interacting Genes		8 interacting genes: AKAP4 BRAP GNA13 PRKAR2A ROPN1 ROPN1B ROPN1L SPA17	50 interacting genes: AKAIN1 AKAP14 AKAP3 AKAP5 AKAP7 AP1M1 BTBD16 CDC37 CEP57L1 CKS1B CNST DBF4B ERCC3 FAM110A FAM153A FAM153B FAM161A FAM90A1 GNL3L GPKOW HNRNPUL1 KIAA0753 KIF9 LENG1 LMO4 LNX1 LNX2 NTAQ1 PICK1 PKP2 POLR3C PRDM6 PRKAA1 PSMA1 RHPN1 RTP5 SDCBP SERTAD1 SORBS3 SPA17 SPG21 SYTL4 TRIM3 TSGA10IP TSHZ3 TSNAXIP1 TULP3 UBE2W VPS33A XKR3
Entrez ID		10566	54763
HPRD ID		05256	15269
Ensembl ID		ENSG00000111254	ENSG00000065371
Uniprot IDs		O75969 V9HWD4	A0A140VKB2 Q9HAT0
PDB IDs
Enriched GO Terms of Interacting Partners?		Cilium Movement Motile Cilium Sperm Capacitation Sperm Motility Flagellated Sperm Motility Cilium-dependent Cell Motility Cilium Movement Involved In Cell Motility Microtubule-based Movement Cilium Sperm Fibrous Sheath CAMP-dependent Protein Kinase Complex Microtubule-based Process Developmental Process Involved In Reproduction Cell Maturation Sperm Principal Piece Developmental Maturation Reproductive Process Small GTPase-mediated Signal Transduction Epithelial Cilium Movement Involved In Extracellular Fluid Movement Extracellular Transport Cilium Organization Protein Localization To Cilium Rho Protein Signal Transduction Cytoplasm Cell Motility D5 Dopamine Receptor Binding Single Fertilization Male Gamete Generation Spermatogenesis Sperm End Piece Gamete Generation Cell Projection Fertilization Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Rho-activating G Protein-coupled Receptor Signaling Pathway CAMP-dependent Protein Kinase Regulator Activity Microtubule-based Transport CAMP-dependent Protein Kinase Inhibitor Activity Adenylate Cyclase-modulating G Protein-coupled Receptor Signaling Pathway Nucleotide-activated Protein Kinase Complex Intracellular Signal Transduction Intracellular Signaling Cassette Radial Spoke Plasma Membrane Bounded Cell Projection Organization Protein Kinase A Catalytic Subunit Binding Sperm Head-tail Coupling Apparatus Guanyl Nucleotide Binding Acrosome Reaction Fusion Of Sperm To Egg Plasma Membrane Involved In Single Fertilization Sperm Flagellum Assembly	Protein Kinase A Binding Protein Binding Protein Kinase A Regulatory Subunit Binding
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