ROPN1 and TSNAXIP1

Number of citations of the paper that reports this interaction (PubMedID 27107012)
72

Data Source:
BioGRID (two hybrid)

		ROPN1	TSNAXIP1
Description		rhophilin associated tail protein 1	translin associated factor X interacting protein 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cilium Motile Cilium Cell Projection	Cytoplasm Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Binding Identical Protein Binding	Protein Binding
	Biological Process	Flagellated Sperm Motility Cilium Organization Sperm Capacitation Protein Localization To Cilium	Spermatogenesis Cell Differentiation
Pathways		RHO GTPases Activate Rhotekin and Rhophilins
Drugs
Diseases
GWAS		Benign childhood epilepsy with centro-temporal spikes ( 32580138) Household income ( 31844048) Household income (MTAG) ( 31844048)	A body shape index ( 34021172) Empathy quotient ( 29527006) Refractive error ( 32231278) Schizophrenia ( 25056061 29483656) Waist circumference adjusted for body mass index ( 34021172) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)
Interacting Genes		50 interacting genes: AKAIN1 AKAP14 AKAP3 AKAP5 AKAP7 AP1M1 BTBD16 CDC37 CEP57L1 CKS1B CNST DBF4B ERCC3 FAM110A FAM153A FAM153B FAM161A FAM90A1 GNL3L GPKOW HNRNPUL1 KIAA0753 KIF9 LENG1 LMO4 LNX1 LNX2 NTAQ1 PICK1 PKP2 POLR3C PRDM6 PRKAA1 PSMA1 RHPN1 RTP5 SDCBP SERTAD1 SORBS3 SPA17 SPG21 SYTL4 TRIM3 TSGA10IP TSHZ3 TSNAXIP1 TULP3 UBE2W VPS33A XKR3	12 interacting genes: APP CDC7 FAM161B GRAP2 HSPB1 PRPF18 PRPF6 ROPN1 SNW1 SPG21 TSNAX UTP6
Entrez ID		54763	55815
HPRD ID		15269	09656
Ensembl ID		ENSG00000065371	ENSG00000102904
Uniprot IDs		A0A140VKB2 Q9HAT0	B4DXD0 E7ENJ7 Q2TAA8
PDB IDs
Enriched GO Terms of Interacting Partners?		Protein Kinase A Binding Protein Binding Protein Kinase A Regulatory Subunit Binding	Collateral Sprouting Neuron Maturation Cell Maturation RNA Processing Spliceosomal Complex U5 SnRNP Developmental Maturation U4/U6 X U5 Tri-snRNP Complex Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Negative Regulation Of Protein Kinase C Signaling U2-type Post-spliceosomal Complex Positive Regulation Of Interleukin-1 Beta Production Acetylcholine Receptor Activator Activity PTB Domain Binding Positive Regulation Of Interleukin-1 Production Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Axo-dendritic Transport Response To Growth Factor Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Endothelin Production Growth Cone Filopodium Lipoprotein Particle Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Nucleus Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Regulation Of Interleukin-1 Beta Production Protein Kinase C Inhibitor Activity A2A Adenosine Receptor Binding Generation Of Catalytic Spliceosome For Second Transesterification Step RNA Splicing Catalytic Step 2 Spliceosome Microtubule-based Movement Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Intermediate-density Lipoprotein Particle Regulation Of Interleukin-1 Production Axon Midline Choice Point Recognition Positive Regulation Of Tumor Necrosis Factor Production Positive Regulation Of Amyloid Fibril Formation Cellular Response To Norepinephrine Stimulus Growth Factor Receptor Binding Main Axon Developmental Cell Growth
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