ROPN1 and SPA17

Number of citations of the paper that reports this interaction (PubMedID 10591629)
0

Data Source:
HPRD (in vitro)

		ROPN1	SPA17
Description		rhophilin associated tail protein 1	sperm autoantigenic protein 17
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cilium Motile Cilium Cell Projection	Extracellular Region Cytoplasm Cilium External Side Of Plasma Membrane Membrane Motile Cilium Sperm Fibrous Sheath Neuron Projection Sperm Principal Piece
	Molecular Function	Protein Binding Identical Protein Binding	Protein Binding Calmodulin Binding
	Biological Process	Flagellated Sperm Motility Cilium Organization Sperm Capacitation Protein Localization To Cilium	Epithelial Cilium Movement Involved In Extracellular Fluid Movement Spermatogenesis Single Fertilization Binding Of Sperm To Zona Pellucida
Pathways		RHO GTPases Activate Rhotekin and Rhophilins
Drugs
Diseases
GWAS		Benign childhood epilepsy with centro-temporal spikes ( 32580138) Household income ( 31844048) Household income (MTAG) ( 31844048)	Bipolar disorder ( 20351715)
Interacting Genes		50 interacting genes: AKAIN1 AKAP14 AKAP3 AKAP5 AKAP7 AP1M1 BTBD16 CDC37 CEP57L1 CKS1B CNST DBF4B ERCC3 FAM110A FAM153A FAM153B FAM161A FAM90A1 GNL3L GPKOW HNRNPUL1 KIAA0753 KIF9 LENG1 LMO4 LNX1 LNX2 NTAQ1 PICK1 PKP2 POLR3C PRDM6 PRKAA1 PSMA1 RHPN1 RTP5 SDCBP SERTAD1 SORBS3 SPA17 SPG21 SYTL4 TRIM3 TSGA10IP TSHZ3 TSNAXIP1 TULP3 UBE2W VPS33A XKR3	5 interacting genes: ACTN2 AKAP3 AKAP7 MYL6B ROPN1
Entrez ID		54763	53340
HPRD ID		15269	12272
Ensembl ID		ENSG00000065371	ENSG00000064199
Uniprot IDs		A0A140VKB2 Q9HAT0	A0A172Q397 Q15506
PDB IDs			8J07
Enriched GO Terms of Interacting Partners?		Protein Kinase A Binding Protein Binding Protein Kinase A Regulatory Subunit Binding	Positive Regulation Of Potassium Ion Transport Protein Kinase A Binding Structural Constituent Of Muscle Titin Z Domain Binding Intracellular Protein Localization Positive Regulation Of Cation Transmembrane Transport Regulation Of Potassium Ion Transport Actin Filament Uncapping Positive Regulation Of Monoatomic Ion Transmembrane Transport Sperm Motility Flagellated Sperm Motility Cilium Movement Involved In Cell Motility Cilium-dependent Cell Motility Phospholipase C-activating Angiotensin-activated Signaling Pathway Microspike Assembly Positive Regulation Of Monoatomic Ion Transport Cilium Movement FATZ Binding Motile Cilium Structural Constituent Of Postsynaptic Actin Cytoskeleton Channel Activator Activity LIM Domain Binding Sperm Fibrous Sheath Unconventional Myosin Complex Positive Regulation Of Endocytic Recycling Regulation Of Monoatomic Cation Transmembrane Transport Regulation Of Monoatomic Ion Transmembrane Transport Postsynaptic Actin Cytoskeleton Positive Regulation Of Actin Filament Depolymerization Negative Regulation Of Protein Localization To Cell Surface Cell Projection Titin Binding Regulation Of Metal Ion Transport Actin Filament-based Process Postsynaptic Density, Intracellular Component Postsynaptic Actin Cytoskeleton Organization Positive Regulation Of Protein Depolymerization Regulation Of Monoatomic Ion Transport Pseudopodium Microtubule-based Movement Acrosome Reaction Sperm Capacitation Muscle Myosin Complex Actin-myosin Filament Sliding Muscle Filament Sliding Angiotensin-activated Signaling Pathway Regulation Of Endocytic Recycling Postsynaptic Cytoskeleton Organization Regulation Of Membrane Potential Positive Regulation Of Cation Channel Activity
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