AKAP3 and SPA17

Number of citations of the paper that reports this interaction (PMID 15257753)
7

Data Source:
HPRD (in vitro)

		AKAP3	SPA17
Gene Name		A kinase (PRKA) anchor protein 3	sperm autoantigenic protein 17
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Acrosomal Vesicle Nucleus Cytoplasm Sperm Fibrous Sheath Sperm Principal Piece	Cytoplasm Membrane Motile Cilium Primary Cilium
	Molecular Function	Protein Binding Protein Kinase A Binding	Calmodulin Binding
	Biological Process	Movement Of Cell Or Subcellular Component Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Single Fertilization Acrosome Reaction Protein Localization Regulation Of Protein Kinase A Signaling	Epithelial Cilium Movement Spermatogenesis Single Fertilization Binding Of Sperm To Zona Pellucida
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		7 interactors: AKAP4 GNA13 PRKAR2A ROPN1 ROPN1B ROPN1L SPA17	4 interactors: AKAP3 AKAP7 MYL6B ROPN1
Entrez ID		10566	53340
HPRD ID		05256	12272
Ensembl ID		ENSG00000111254	ENSG00000064199
Uniprot IDs		O75969	Q15506
PDB IDs
Enriched GO Terms of Interacting Partners?		Sperm Motility Single Fertilization Movement Of Cell Or Subcellular Component Fertilization Epithelial Cilium Movement Sexual Reproduction Reproduction Cilium Movement Single Organism Reproductive Process Rho Protein Signal Transduction Reproductive Process Positive Regulation Of Phospholipase Activity Spermatogenesis Male Gamete Generation Regulation Of Phospholipase Activity Positive Regulation Of Lipase Activity Gamete Generation Multicellular Organismal Reproductive Process Multicellular Organism Reproduction Cell Motility Ras Protein Signal Transduction Negative Regulation Of CAMP-dependent Protein Kinase Activity Microtubule-based Movement Locomotion Regulation Of CAMP-dependent Protein Kinase Activity Activation Of Phospholipase D Activity Activation Of Protein Kinase A Activity Regulation Of Protein Kinase A Signaling Fusion Of Sperm To Egg Plasma Membrane Sperm Capacitation Blood Coagulation Hemostasis Plasma Membrane Fusion Acrosome Reaction Renal Water Homeostasis Intracellular Signal Transduction Regulation Of Body Fluid Levels Wound Healing Small GTPase Mediated Signal Transduction Cellular Response To Glucagon Stimulus Water Transport Binding Of Sperm To Zona Pellucida See more	Positive Regulation Of Delayed Rectifier Potassium Channel Activity Regulation Of Delayed Rectifier Potassium Channel Activity Positive Regulation Of Potassium Ion Transmembrane Transporter Activity Regulation Of Protein Kinase A Signaling Positive Regulation Of Potassium Ion Transmembrane Transport Regulation Of Membrane Repolarization Acrosome Reaction Regulation Of Potassium Ion Transmembrane Transporter Activity Positive Regulation Of Potassium Ion Transport Muscle Filament Sliding Actin-myosin Filament Sliding Positive Regulation Of Cation Channel Activity Regulation Of Potassium Ion Transmembrane Transport Actin-mediated Cell Contraction Calcium Ion-dependent Exocytosis Cellular Response To CAMP Positive Regulation Of Ion Transmembrane Transporter Activity Positive Regulation Of Transporter Activity Regulation Of Potassium Ion Transport Actin Filament-based Movement Positive Regulation Of Ion Transmembrane Transport Regulation Of Cation Channel Activity Action Potential Movement Of Cell Or Subcellular Component See more
Tagcloud ?		acev2 acu akap4v2 configurations degenerate frames gapdhs hundreds hypothetical noncanonical odf1 orthologous paralogues permutations prm1 prm2 prm3 resemble retrogene retroposons smcp spata18 spermatids tnp1 tnp2 uac utrs yrs yrss	aspirates bage bage1 cover ct ct7 eso gage gammopathies lage magea1 magea10 magea12 magea2 magea3 magea4 magec1 mgus ny plasmacytoma plasmacytomas prame solitary ssx ssx1 testis tonsils u266 undetermined
Tagcloud (Difference) ?		acev2 acu akap4v2 configurations degenerate frames gapdhs hundreds hypothetical noncanonical odf1 orthologous paralogues permutations prm1 prm2 prm3 resemble retrogene retroposons smcp spata18 spermatids tnp1 tnp2 uac utrs yrs yrss	aspirates bage bage1 cover ct ct7 eso gage gammopathies lage magea1 magea10 magea12 magea2 magea3 magea4 magec1 mgus ny plasmacytoma plasmacytomas prame solitary ssx ssx1 testis tonsils u266 undetermined
Tagcloud (Intersection) ?