AKAP3 and AKAP4

Number of citations of the paper that reports this interaction (PMID 12606363)
13

Data Source:
HPRD (in vitro, two hybrid)

		AKAP3	AKAP4
Gene Name		A kinase (PRKA) anchor protein 3	A kinase (PRKA) anchor protein 4
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Acrosomal Vesicle Nucleus Cytoplasm Sperm Fibrous Sheath Sperm Principal Piece	Nucleus Cytoplasm Cytoskeleton CAMP-dependent Protein Kinase Complex Z Disc Motile Cilium Sperm Fibrous Sheath Perinuclear Region Of Cytoplasm Sperm Principal Piece
	Molecular Function	Protein Binding Protein Kinase A Binding	Protein Kinase A Binding
	Biological Process	Movement Of Cell Or Subcellular Component Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Single Fertilization Acrosome Reaction Protein Localization Regulation Of Protein Kinase A Signaling	Movement Of Cell Or Subcellular Component Signal Transduction Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Single Fertilization Protein Localization Regulation Of Protein Kinase A Signaling Cell Projection Organization Sperm Motility
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		7 interactors: AKAP4 GNA13 PRKAR2A ROPN1 ROPN1B ROPN1L SPA17	6 interactors: AKAP3 FSIP1 FSIP2 PRKAR1A PRKAR2A PRKAR2B
Entrez ID		10566	8852
HPRD ID		05256	02173
Ensembl ID		ENSG00000111254	ENSG00000147081
Uniprot IDs		O75969	Q5JQC9
PDB IDs
Enriched GO Terms of Interacting Partners?		Sperm Motility Single Fertilization Movement Of Cell Or Subcellular Component Fertilization Epithelial Cilium Movement Sexual Reproduction Reproduction Cilium Movement Single Organism Reproductive Process Rho Protein Signal Transduction Reproductive Process Positive Regulation Of Phospholipase Activity Spermatogenesis Male Gamete Generation Regulation Of Phospholipase Activity Positive Regulation Of Lipase Activity Gamete Generation Multicellular Organismal Reproductive Process Multicellular Organism Reproduction Cell Motility Ras Protein Signal Transduction Negative Regulation Of CAMP-dependent Protein Kinase Activity Microtubule-based Movement Locomotion Regulation Of CAMP-dependent Protein Kinase Activity Activation Of Phospholipase D Activity Activation Of Protein Kinase A Activity Regulation Of Protein Kinase A Signaling Fusion Of Sperm To Egg Plasma Membrane Sperm Capacitation Blood Coagulation Hemostasis Plasma Membrane Fusion Acrosome Reaction Renal Water Homeostasis Intracellular Signal Transduction Regulation Of Body Fluid Levels Wound Healing Small GTPase Mediated Signal Transduction Cellular Response To Glucagon Stimulus Water Transport Binding Of Sperm To Zona Pellucida	Negative Regulation Of CAMP-dependent Protein Kinase Activity Regulation Of CAMP-dependent Protein Kinase Activity Activation Of Protein Kinase A Activity Renal Water Homeostasis Cellular Response To Glucagon Stimulus Water Transport Fluid Transport Multicellular Organismal Water Homeostasis Activation Of Phospholipase C Activity Response To Glucagon Positive Regulation Of Phospholipase C Activity Water Homeostasis Positive Regulation Of Phospholipase Activity Regulation Of Phospholipase Activity Positive Regulation Of Lipase Activity Renal System Process Negative Regulation Of Protein Serine/threonine Kinase Activity Energy Reserve Metabolic Process Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Fibroblast Growth Factor Receptor Signaling Pathway Cellular Response To Fibroblast Growth Factor Stimulus Response To Fibroblast Growth Factor Enzyme Linked Receptor Protein Signaling Pathway Regulation Of Insulin Secretion Negative Regulation Of Protein Kinase Activity Neurotrophin TRK Receptor Signaling Pathway Regulation Of Peptide Hormone Secretion Neurotrophin Signaling Pathway Negative Regulation Of Kinase Activity Regulation Of Hormone Secretion Activation Of Protein Kinase Activity Negative Regulation Of Transferase Activity Energy Derivation By Oxidation Of Organic Compounds Negative Regulation Of Protein Phosphorylation Cellular Response To Peptide Hormone Stimulus Cellular Response To Peptide Negative Regulation Of Phosphorylation Regulation Of Protein Secretion Generation Of Precursor Metabolites And Energy Blood Coagulation Hemostasis Response To Peptide Hormone Positive Regulation Of Protein Kinase Activity Cellular Response To Organonitrogen Compound Response To Peptide Positive Regulation Of Kinase Activity Positive Regulation Of Transferase Activity Regulation Of Body Fluid Levels Cellular Response To Growth Factor Stimulus
Tagcloud ?		acev2 acu akap4v2 configurations degenerate frames gapdhs hundreds hypothetical noncanonical odf1 orthologous paralogues permutations prm1 prm2 prm3 resemble retrogene retroposons smcp spata18 spermatids tnp1 tnp2 uac utrs yrs yrss	allowing applying classification comprehensive ct dominance encode frequencies germ guiding heterogeneous immunogenic immunotherapy libraries location normally otoa panel pepp ranking restricted silico somatic survey tags technologies testis twice wide
Tagcloud (Difference) ?		acev2 acu akap4v2 configurations degenerate frames gapdhs hundreds hypothetical noncanonical odf1 orthologous paralogues permutations prm1 prm2 prm3 resemble retrogene retroposons smcp spata18 spermatids tnp1 tnp2 uac utrs yrs yrss	allowing applying classification comprehensive ct dominance encode frequencies germ guiding heterogeneous immunogenic immunotherapy libraries location normally otoa panel pepp ranking restricted silico somatic survey tags technologies testis twice wide
Tagcloud (Intersection) ?