ROPN1 and AKAP14

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		ROPN1	AKAP14
Description		rhophilin associated tail protein 1	A-kinase anchoring protein 14
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cilium Motile Cilium Cell Projection	Cytoplasm Axoneme CAMP-dependent Protein Kinase Complex
	Molecular Function	Protein Binding Identical Protein Binding	Protein Binding Protein Kinase A Regulatory Subunit Binding
	Biological Process	Flagellated Sperm Motility Cilium Organization Sperm Capacitation Protein Localization To Cilium
Pathways		RHO GTPases Activate Rhotekin and Rhophilins
Drugs
Diseases
GWAS		Benign childhood epilepsy with centro-temporal spikes ( 32580138) Household income ( 31844048) Household income (MTAG) ( 31844048)
Interacting Genes		50 interacting genes: AKAIN1 AKAP14 AKAP3 AKAP5 AKAP7 AP1M1 BTBD16 CDC37 CEP57L1 CKS1B CNST DBF4B ERCC3 FAM110A FAM153A FAM153B FAM161A FAM90A1 GNL3L GPKOW HNRNPUL1 KIAA0753 KIF9 LENG1 LMO4 LNX1 LNX2 NTAQ1 PICK1 PKP2 POLR3C PRDM6 PRKAA1 PSMA1 RHPN1 RTP5 SDCBP SERTAD1 SORBS3 SPA17 SPG21 SYTL4 TRIM3 TSGA10IP TSHZ3 TSNAXIP1 TULP3 UBE2W VPS33A XKR3	8 interacting genes: DPY30 FBXO7 PRKACA PRKAR1B PRKAR2A PRKAR2B ROPN1 ROPN1L
Entrez ID		54763	158798
HPRD ID		15269	02353
Ensembl ID		ENSG00000065371	ENSG00000186471
Uniprot IDs		A0A140VKB2 Q9HAT0	Q86UN6
PDB IDs
Enriched GO Terms of Interacting Partners?		Protein Kinase A Binding Protein Binding Protein Kinase A Regulatory Subunit Binding	CAMP-dependent Protein Kinase Complex Ciliary Base CAMP-dependent Protein Kinase Regulator Activity CAMP-dependent Protein Kinase Inhibitor Activity Protein Kinase A Catalytic Subunit Binding Sperm Capacitation CAMP Binding Negative Regulation Of CAMP/PKA Signal Transduction Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Regulation Of CAMP/PKA Signal Transduction Adenylate Cyclase-modulating G Protein-coupled Receptor Signaling Pathway Ubiquitin Protein Ligase Binding Negative Regulation Of Intracellular Signal Transduction Nucleotide-activated Protein Kinase Complex Cell Maturation Developmental Maturation Motile Cilium Plasma Membrane Raft Protein Domain Specific Binding Postsynapse Negative Regulation Of Signal Transduction Negative Regulation Of Signaling Negative Regulation Of Cell Communication G Protein-coupled Receptor Signaling Pathway Glial Cytoplasmic Inclusion Classical Lewy Body Lewy Body Corona Lewy Neurite Regulation Of Intracellular Signal Transduction Protein Kinase Binding Response To Antipsychotic Drug Modulation Of Chemical Synaptic Transmission Axoneme Lewy Body Core Sperm Motility Flagellated Sperm Motility Cilium-dependent Cell Motility Cilium Movement Involved In Cell Motility Negative Regulation Of Glycolytic Process Through Fructose-6-phosphate Protein Localization To Lipid Droplet Cilium Glutamatergic Synapse Centrosome CAMP-dependent Protein Kinase Activity Cilium Movement Channel Activator Activity Regulation Of Macroautophagy Positive Regulation Of Fear Response CAMP/PKA Signal Transduction Vascular Endothelial Cell Response To Laminar Fluid Shear Stress
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