MYBBP1A and ANXA1

Number of citations of the paper that reports this interaction (PubMedID 37001908)
48

Data Source:
BioGRID (unspecified method)

		MYBBP1A	ANXA1
Description		MYB binding protein 1a	annexin A1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Cytoplasm Membrane NLS-dependent Protein Nuclear Import Complex B-WICH Complex	Cornified Envelope Phagocytic Cup Extracellular Region Extracellular Space Nucleus Nucleoplasm Cytoplasm Endosome Early Endosome Cytosol Actin Filament Plasma Membrane Adherens Junction Focal Adhesion Cilium Cell Surface Endosome Membrane Vesicle Membrane Membrane Basolateral Plasma Membrane Apical Plasma Membrane Lateral Plasma Membrane Cytoplasmic Vesicle Membrane Extracellular Matrix Cytoplasmic Vesicle Motile Cilium Early Endosome Membrane Vesicle Sarcolemma Cell Projection Extracellular Exosome
	Molecular Function	DNA Binding Transcription Corepressor Activity RNA Binding Sequence-specific DNA Binding E-box Binding	Phosphatidylserine Binding Phospholipase Inhibitor Activity Signaling Receptor Binding Calcium Ion Binding Protein Binding Phospholipid Binding Calcium-dependent Phospholipid Binding Lipid Binding Phospholipase A2 Inhibitor Activity Metal Ion Binding Calcium-dependent Protein Binding Cadherin Binding Involved In Cell-cell Adhesion
	Biological Process	Osteoblast Differentiation Chromatin Remodeling Regulation Of DNA-templated Transcription Respiratory Electron Transport Chain Circadian Regulation Of Gene Expression Cellular Response To Glucose Starvation Ribosome Biogenesis Negative Regulation Of DNA-templated Transcription Positive Regulation Of Transcription By RNA Polymerase I Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Transcription By RNA Polymerase III Rhythmic Process Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Regulation Of G1 To G0 Transition Positive Regulation Of Anoikis	Neutrophil Homeostasis Adaptive Immune Response Immune System Process Monocyte Chemotaxis Regulation Of Leukocyte Migration Phagocytosis Inflammatory Response Signal Transduction Cell Surface Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Regulation Of Cell Shape Myoblast Migration Involved In Skeletal Muscle Regeneration Peptide Cross-linking Actin Cytoskeleton Organization Keratinocyte Differentiation Positive Regulation Of Vesicle Fusion Regulation Of Interleukin-1 Production Negative Regulation Of Interleukin-8 Production Positive Regulation Of Interleukin-2 Production Positive Regulation Of Neutrophil Apoptotic Process Cellular Response To Vascular Endothelial Growth Factor Stimulus Positive Regulation Of T Cell Proliferation Neutrophil Activation Regulation Of Cell Population Proliferation Negative Regulation Of Apoptotic Process Innate Immune Response Positive Regulation Of T-helper 1 Cell Differentiation Negative Regulation Of T-helper 2 Cell Differentiation Negative Regulation Of Exocytosis Alpha-beta T Cell Differentiation Regulation Of Hormone Secretion Arachidonate Secretion Regulation Of Inflammatory Response Negative Regulation Of Transport Positive Regulation Of Multicellular Organismal Process Cellular Response To Glucocorticoid Stimulus Granulocyte Chemotaxis Positive Regulation Of Cell Migration Involved In Sprouting Angiogenesis Positive Regulation Of Wound Healing Neutrophil Clearance Cell-cell Adhesion Positive Regulation Of G1/S Transition Of Mitotic Cell Cycle
Pathways		B-WICH complex positively regulates rRNA expression	G alpha (q) signalling events G alpha (i) signalling events Formyl peptide receptors bind formyl peptides and many other ligands Smooth Muscle Contraction Interleukin-4 and Interleukin-13 signaling Developmental Lineage of Pancreatic Ductal Cells
Drugs			Amcinonide Fluocinolone acetonide Hydrocortisone Methylprednisolone Clobetasol propionate Budesonide Dexamethasone Cortisone acetate Hydrocortisone aceponate Hydrocortisone acetate Hydrocortisone butyrate Hydrocortisone cypionate Hydrocortisone phosphate Hydrocortisone probutate Hydrocortisone valerate Prednisolone phosphate Dexamethasone acetate Betamethasone phosphate
Diseases
GWAS			Chronotype ( 30696823) Cortical surface area ( 32963231) Cortical volume ( 32963231) Metabolite levels ( 23823483) Parkinson's disease ( 26227905) Schizophrenia, bipolar disorder and depression (combined) ( 20713499) Urate levels in obese individuals ( 25811787)
Interacting Genes		17 interacting genes: ANXA1 APP AR DHX30 DUX4 ESR1 HOXB9 JUN MYB NR2E3 PCNA PPARGC1A PTEN RNF10 TP53 UBE2I USP7	80 interacting genes: AP2A2 APBB1 BUB3 CCN1 CCT7 CD274 CD44 CDC5L CDH13 CLIC1 CLTC COPS6 CORO1C CSAD CZIB DAPK3 DDB1 DDX3X DYSF EEF2 EGFR EIF2S1 EPHA2 ERG28 FAF1 FGFBP1 FLOT1 FLOT2 FPR1 G3BP2 GAPDH GAPDHS GNL3 HMGA1 HSP90AB1 HSPB1 IFIT1 IFIT3 IGF2BP1 IGF2BP3 KLHL23 KMT2B KRT8 LGALS3 LGALS8 LMNA LMO7 LNPK LRIF1 MEIS2 MEN1 MYBBP1A MYH10 MYH9 NOP58 OTUB1 PARP1 PARP9 PHB2 PRKCI RCC2 S100A11 SRC STRAP SUMO2 TCP1 TGM2 TOE1 TRAF4 TRPM7 UBE2D1 UBE2I UBE3A UCHL5 UGDH UNC119 USP7 XRCC1 XRCC6 YWHAQ
Entrez ID		10514	301
HPRD ID		05349	01060
Ensembl ID		ENSG00000132382	ENSG00000135046
Uniprot IDs		Q9BQG0	P04083 Q5TZZ9
PDB IDs			1AIN 1BO9 1QLS 5VFW
Enriched GO Terms of Interacting Partners?		Regulation Of MiRNA Transcription Positive Regulation Of Transcription By RNA Polymerase II Regulation Of MiRNA Metabolic Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Enzyme Binding Positive Regulation Of Biosynthetic Process Regulation Of Cell Population Proliferation Positive Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Positive Regulation Of DNA-templated Transcription Positive Regulation Of Metabolic Process Positive Regulation Of RNA Metabolic Process Negative Regulation Of Cell Population Proliferation Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Gene Expression Positive Regulation Of Macromolecule Metabolic Process Regulation Of Macromolecule Biosynthetic Process DNA Binding Nucleus PML Body Negative Regulation Of Transcription By RNA Polymerase II DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Rhythmic Process Regulation Of Macromolecule Metabolic Process Chromatin Binding Positive Regulation Of MiRNA Transcription Negative Regulation Of Macromolecule Metabolic Process Nucleoplasm Positive Regulation Of MiRNA Metabolic Process Regulation Of Metabolic Process Regulation Of Primary Metabolic Process Negative Regulation Of Metabolic Process Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Biosynthetic Process Nuclear Steroid Receptor Activity RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Regulation Of Fibroblast Proliferation DNA-binding Transcription Factor Activity Negative Regulation Of RNA Metabolic Process Regulation Of Neuron Apoptotic Process Transcription Cis-regulatory Region Binding Negative Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Glial Cell Proliferation Central Nervous System Development	Regulation Of Primary Metabolic Process Regulation Of Protein Metabolic Process Regulation Of Macromolecule Metabolic Process Focal Adhesion Negative Regulation Of Macromolecule Metabolic Process Regulation Of Telomere Maintenance Regulation Of Metabolic Process Positive Regulation Of Metabolic Process Cytosol Nucleus RNA Binding Positive Regulation Of Protein Localization Negative Regulation Of Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Biosynthetic Process Positive Regulation Of Macromolecule Metabolic Process Cytoplasm Extracellular Exosome MRNA 5'-UTR Binding Positive Regulation Of Signal Transduction Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Chromosome Organization Regulation Of Protein Modification Process Regulation Of Macromolecule Biosynthetic Process Regulation Of Apoptotic Process Regulation Of DNA Metabolic Process Regulation Of Programmed Cell Death Regulation Of Protein Localization Regulation Of Cell Adhesion Perinuclear Region Of Cytoplasm Biological Process Involved In Interaction With Host Positive Regulation Of Protein Metabolic Process Regulation Of Cellular Component Organization Positive Regulation Of Cell Communication Positive Regulation Of Signaling Negative Regulation Of Macromolecule Biosynthetic Process Signal Transduction Cellular Response To Stress Negative Regulation Of Biosynthetic Process Regulation Of Signal Transduction Positive Regulation Of Nucleobase-containing Compound Metabolic Process Lamellipodium Negative Regulation Of Protein Metabolic Process Regulation Of Signaling Intracellular Signal Transduction Response To Stress Regulation Of Gene Expression Disordered Domain Specific Binding Flotillin Complex Protein Binding
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