MYBBP1A and NR2E3

Number of citations of the paper that reports this interaction (PubMedID 17255935)
48

Data Source:
HPRD (in vivo)

		MYBBP1A	NR2E3
Description		MYB binding protein 1a	nuclear receptor subfamily 2 group E member 3
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Cytoplasm Membrane NLS-dependent Protein Nuclear Import Complex B-WICH Complex	Nucleus Nucleoplasm Transcription Regulator Complex
	Molecular Function	DNA Binding Transcription Corepressor Activity RNA Binding Sequence-specific DNA Binding E-box Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Nuclear Steroid Receptor Activity Nuclear Receptor Activity Protein Binding Zinc Ion Binding Sequence-specific DNA Binding Metal Ion Binding
	Biological Process	Osteoblast Differentiation Chromatin Remodeling Regulation Of DNA-templated Transcription Respiratory Electron Transport Chain Circadian Regulation Of Gene Expression Cellular Response To Glucose Starvation Ribosome Biogenesis Negative Regulation Of DNA-templated Transcription Positive Regulation Of Transcription By RNA Polymerase I Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Transcription By RNA Polymerase III Rhythmic Process Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Regulation Of G1 To G0 Transition Positive Regulation Of Anoikis	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of DNA-templated Transcription Signal Transduction Visual Perception Phototransduction Cell Population Proliferation Negative Regulation Of Cell Population Proliferation Positive Regulation Of Gene Expression Neuron Differentiation Nuclear Receptor-mediated Steroid Hormone Signaling Pathway Intracellular Receptor Signaling Pathway Eye Photoreceptor Cell Development Positive Regulation Of Transcription By RNA Polymerase II Retina Development In Camera-type Eye
Pathways		B-WICH complex positively regulates rRNA expression
Drugs
Diseases			Retinitis pigmentosa (RP) Vitreoretinal degeneration, including: Stickler syndrome type I (STL1); Stickler syndrome type II (STL2); Snowflake vitreoretinal degeneration (SVD); Wagner syndrome 1 (WGN1); Knobloch syndrome (KNO); Enhanced S-cone syndrome (ESCS); Autosomal dominant vitreoretinochoroidopathy (ADVIRC)
GWAS			Hematocrit ( 32888494) Hemoglobin ( 32888494) Macular thickness ( 30535121) Metabolite levels (HVA/MHPG ratio) ( 23319000) Red blood cell count ( 32888494)
Interacting Genes		17 interacting genes: ANXA1 APP AR DHX30 DUX4 ESR1 HOXB9 JUN MYB NR2E3 PCNA PPARGC1A PTEN RNF10 TP53 UBE2I USP7	29 interacting genes: BCL11A CDK9 CRX DEDD2 DHX30 ELAVL2 HDAC1 HDAC3 HOXC13 IRF9 MYBBP1A NCOR1 NR1D1 NR3C1 NRL POLR3D PPARG RARA RBBP4 RBBP7 RBFOX2 RBL1 RXRA RXRB SIN3A SNAPC1 TBL3 WDR5 ZNF232
Entrez ID		10514	10002
HPRD ID		05349	05132
Ensembl ID		ENSG00000132382	ENSG00000278570
Uniprot IDs		Q9BQG0	F1D8Q9 Q9Y5X4
PDB IDs			4LOG
Enriched GO Terms of Interacting Partners?		Regulation Of MiRNA Transcription Positive Regulation Of Transcription By RNA Polymerase II Regulation Of MiRNA Metabolic Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Enzyme Binding Positive Regulation Of Biosynthetic Process Regulation Of Cell Population Proliferation Positive Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Positive Regulation Of DNA-templated Transcription Positive Regulation Of Metabolic Process Positive Regulation Of RNA Metabolic Process Negative Regulation Of Cell Population Proliferation Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Gene Expression Positive Regulation Of Macromolecule Metabolic Process Regulation Of Macromolecule Biosynthetic Process DNA Binding Nucleus PML Body Negative Regulation Of Transcription By RNA Polymerase II DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Rhythmic Process Regulation Of Macromolecule Metabolic Process Chromatin Binding Positive Regulation Of MiRNA Transcription Negative Regulation Of Macromolecule Metabolic Process Nucleoplasm Positive Regulation Of MiRNA Metabolic Process Regulation Of Metabolic Process Regulation Of Primary Metabolic Process Negative Regulation Of Metabolic Process Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Biosynthetic Process Nuclear Steroid Receptor Activity RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Regulation Of Fibroblast Proliferation DNA-binding Transcription Factor Activity Negative Regulation Of RNA Metabolic Process Regulation Of Neuron Apoptotic Process Transcription Cis-regulatory Region Binding Negative Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Glial Cell Proliferation Central Nervous System Development	Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process DNA Binding Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Regulation Of Transcription By RNA Polymerase II Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of RNA Metabolic Process Nucleoplasm Negative Regulation Of Nucleobase-containing Compound Metabolic Process Chromatin Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Transcription Cis-regulatory Region Binding Nucleus Positive Regulation Of RNA Metabolic Process Histone Deacetylase Complex Negative Regulation Of Transcription By RNA Polymerase II RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Regulation Of Macromolecule Metabolic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Primary Metabolic Process Positive Regulation Of Transcription By RNA Polymerase II Nuclear Receptor Activity Nuclear Receptor-mediated Signaling Pathway Negative Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Biosynthetic Process Regulation Of Metabolic Process Positive Regulation Of Biosynthetic Process Chromatin Binding Hormone-mediated Signaling Pathway DNA-binding Transcription Factor Activity Negative Regulation Of Macromolecule Metabolic Process Transcription By RNA Polymerase II Sequence-specific Double-stranded DNA Binding DNA-templated Transcription Positive Regulation Of Macromolecule Metabolic Process Negative Regulation Of Metabolic Process Sin3-type Complex Chromatin Organization Retinoic Acid Receptor Signaling Pathway Intracellular Receptor Signaling Pathway Negative Regulation Of Stem Cell Population Maintenance Positive Regulation Of Metabolic Process Retinoic Acid-responsive Element Binding Nucleic Acid Metabolic Process
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