STK25 and ZDHHC17

Number of citations of the paper that reports this interaction (PubMedID 24705354)
111

Data Source:
BioGRID (two hybrid)

		STK25	ZDHHC17
Description		serine/threonine kinase 25	zDHHC palmitoyltransferase 17
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GO Annotations	Cellular Component	Cytoplasm Golgi Apparatus Extracellular Exosome FAR/SIN/STRIPAK Complex	Golgi Membrane Golgi Apparatus Plasma Membrane Membrane Cytoplasmic Vesicle Membrane Golgi-associated Vesicle Membrane Cytoplasmic Vesicle Presynaptic Membrane Cell Projection Synapse Glutamatergic Synapse Perforant Pathway To Dendrate Granule Cell Synapse Postsynaptic Golgi Apparatus
	Molecular Function	Nucleotide Binding Protein Kinase Activity Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Kinase Activity Transferase Activity Protein Homodimerization Activity Metal Ion Binding Protein Serine Kinase Activity	Signaling Receptor Binding Protein Binding Palmitoyltransferase Activity Transferase Activity Acyltransferase Activity Protein-cysteine S-myristoyltransferase Activity Protein-cysteine S-palmitoyltransferase Activity Identical Protein Binding Protein-cysteine S-stearoyltransferase Activity
	Biological Process	Protein Phosphorylation Response To Oxidative Stress Establishment Or Maintenance Of Cell Polarity Signal Transduction Axonogenesis Positive Regulation Of Stress-activated MAPK Cascade Cellular Response To Oxidative Stress Intracellular Signal Transduction Intrinsic Apoptotic Signaling Pathway In Response To Hydrogen Peroxide Protein Autophosphorylation Positive Regulation Of Axonogenesis Golgi Localization Establishment Of Golgi Localization Golgi Reassembly	Axonogenesis Protein Palmitoylation Lipoprotein Transport Regulation Of Programmed Cell Death Positive Regulation Of Canonical NF-kappaB Signal Transduction Regulation Of Neurotrophin TRK Receptor Signaling Pathway Regulation Of ERK1 And ERK2 Cascade Regulation Of Modification Of Synapse Structure, Modulating Synaptic Transmission
Pathways
Drugs
Diseases
GWAS		Medication use (thyroid preparations) ( 31015401) Prostate cancer ( 23535732) Vitiligo ( 27723757)	Mean arterial pressure x educational attainment (some college) interaction (2df) ( 32372009) Metabolite levels ( 23823483) Visceral fat ( 30942860)
Interacting Genes		17 interacting genes: APP CCNDBP1 CEP70 GOLGA2 GOLGA6L9 IHO1 IKBKG LRRK2 MFHAS1 MTDH NEDD4 OGT PDCD10 TRIM27 UBE2D3 YWHAZ ZDHHC17	192 interacting genes: ABCG4 ACTR1B ADD1 AHDC1 AIDA AK3 ALKBH3 ANKRD50 ANXA11 APBB1IP ARFGAP3 ASF1A ASIC4 BCAS3 BEX2 BTF3 C1orf216 C20orf141 CBS CCDC120 CCDC7 CCNE2 CDSN CENPBD2P CHMP1A CIB1 CLRN3 CNDP2 CNKSR1 COG3 CSTA CTCFL CTHRC1 DALRD3 DELE1 DIXDC1 DLG4 DLK1 DR1 DTX3 E2F8 EDRF1 EEF1G ERCC6L EVL EXOSC9 EYA3 FAM9A FBH1 FOXD4L6 FTL FUT2 FUT9 GABPB1 GABPB2 GATA1 GOLPH3L GPR135 GRB10 GUSBP3 H2AP H2BC9 H3C10 HBG1 HECTD3 HLA-A HLA-DRB1 HMBS HOXA3 HS1BP3 HTT IFT20 IFT57 INPP5D JMJD7-PLA2G4B KHDC4 KIAA0408 KNSTRN KRAS KRT17 KRT8P12 KRTAP11-1 KRTAP9-2 LCA5L LCMT1P1 LGALS9C LIN28A LMAN2L LNCRI LRRC45 LY6G6C MANF MAP2K4 MAP3K19 MIIP MLH3 MRFAP1 MRFAP1L1 MSANTD3 MSRB2 MYBPHL MYOZ2 NCBP1 NEBL NFATC2IP NFYC NIFK NPFF ODF2 OFCC1 OTUD7B OTX2 PABIR3 PBRM1 PDZK1IP1 PHF5A PLEKHB1 PPP1R21 PPTC7 PRMT5 PTMA QRICH1 RAB39B RAD51 RANGRF RAP1B RBM5 RCAN3 RIC8A RNF20 RNF38 RSBN1L RUBCNL SCNM1 SEMA4G SF3A3 SHOX2 SKA3 SLC1A3 SLC25A31 SLC9A9 SLX9 SMARCB1 SNAP25 SOX14 SP2 SPRY3 SPRY4 SREBF2 SRSF4 STK25 STN1 SUMF2 SYT1 TEAD1 THAP7 TIGD1 TMC6 TMCC1 TMEM115 TMEM186 TMTC1 TNFAIP1 TNFSF10 TOX TPGS2 TTC23 TTLL7 TUT7 TXNDC12 TXNDC15 UBAC1 UBE2K USP18 USP32 VN1R10P VSX2 WAC WDR20 YIF1A YTHDF3 ZCCHC17 ZFC3H1 ZFP2 ZFP36 ZFYVE19 ZNF333 ZNF341 ZNF597 ZNF624 ZNF667-AS1 ZSCAN9
Entrez ID		10494	23390
HPRD ID		03770	09697
Ensembl ID		ENSG00000115694	ENSG00000186908
Uniprot IDs		A0A024R4B2 A0A0S2Z4Y2 B3KRS6 B4DMA5 B4DVS7 B4E185 O00506 Q96BA2	A8KA01 Q8IUH5
PDB IDs		2XIK 3W8H 4NZW 7Z4V	3EU9 5W7I 5W7J
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Intracellular Signal Transduction Regulation Of Synapse Organization Positive Regulation Of Protein Metabolic Process Cellular Response To Catecholamine Stimulus Positive Regulation Of Signal Transduction Response To Catecholamine Regulation Of Intracellular Signal Transduction Regulation Of Autophagy Positive Regulation Of Proteolysis Positive Regulation Of Cell Communication Negative Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Signaling Negative Regulation Of Signal Transduction Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway Regulation Of Signal Transduction Negative Regulation Of Signaling Regulation Of Programmed Cell Death Negative Regulation Of Cell Communication Golgi Organization Golgi Reassembly Protein Modification Process Positive Regulation Of Catabolic Process Phosphoserine Residue Binding Negative Regulation Of Protein Localization To Nucleus Negative Regulation Of Metabolic Process Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of DNA-templated Transcription Regulation Of Protein Localization Cellular Response To Dopamine Regulation Of Cellular Response To Growth Factor Stimulus Negative Regulation Of RNA Biosynthetic Process Regulation Of Cell Communication Regulation Of Signaling Negative Regulation Of Biosynthetic Process Intracellular Signal Transduction Response To Dopamine Positive Regulation Of Autophagy Establishment Of Golgi Localization Innate Immune Response Regulation Of Proteolysis Cellular Response To Manganese Ion Regulation Of MAPK Cascade Negative Regulation Of RNA Metabolic Process Positive Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Progesterone Receptor Signaling Pathway Regulation Of Protein Metabolic Process Negative Regulation Of Macromolecule Metabolic Process Defense Response To Symbiont Negative Regulation Of Nucleobase-containing Compound Metabolic Process Establishment Of Localization In Cell	Protein Binding
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