STK25

Description		serine/threonine kinase 25
Image
GO Annotations	Cellular Component	Cytoplasm Golgi Apparatus Extracellular Exosome FAR/SIN/STRIPAK Complex
	Molecular Function	Nucleotide Binding Protein Kinase Activity Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Kinase Activity Transferase Activity Protein Homodimerization Activity Metal Ion Binding Protein Serine Kinase Activity
	Biological Process	Protein Phosphorylation Response To Oxidative Stress Establishment Or Maintenance Of Cell Polarity Signal Transduction Axonogenesis Positive Regulation Of Stress-activated MAPK Cascade Cellular Response To Oxidative Stress Intracellular Signal Transduction Intrinsic Apoptotic Signaling Pathway In Response To Hydrogen Peroxide Protein Autophosphorylation Positive Regulation Of Axonogenesis Golgi Localization Establishment Of Golgi Localization Golgi Reassembly
Pathways
Drugs
Diseases
GWAS		Medication use (thyroid preparations) ( 31015401) Prostate cancer ( 23535732) Vitiligo ( 27723757)
Novel Interacting Genes		1 novel interacting genes: HDAC2
Interacting Genes		17 interacting genes: APP CCNDBP1 CEP70 GOLGA2 GOLGA6L9 IHO1 IKBKG LRRK2 MFHAS1 MTDH NEDD4 OGT PDCD10 TRIM27 UBE2D3 YWHAZ ZDHHC17
Entrez ID		10494
HPRD ID		03770
Ensembl ID		ENSG00000115694
Uniprot IDs		A0A024R4B2 A0A0S2Z4Y2 B3KRS6 B4DMA5 B4DVS7 B4E185 O00506 Q96BA2
PDB IDs		2XIK 3W8H 4NZW 7Z4V
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Intracellular Signal Transduction Regulation Of Synapse Organization Positive Regulation Of Protein Metabolic Process Cellular Response To Catecholamine Stimulus Positive Regulation Of Signal Transduction Response To Catecholamine Regulation Of Intracellular Signal Transduction Regulation Of Autophagy Positive Regulation Of Proteolysis Positive Regulation Of Cell Communication Negative Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Signaling Negative Regulation Of Signal Transduction Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway Regulation Of Signal Transduction Negative Regulation Of Signaling Regulation Of Programmed Cell Death Negative Regulation Of Cell Communication Golgi Organization Golgi Reassembly Protein Modification Process Positive Regulation Of Catabolic Process Phosphoserine Residue Binding Negative Regulation Of Protein Localization To Nucleus Negative Regulation Of Metabolic Process Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of DNA-templated Transcription Regulation Of Protein Localization Cellular Response To Dopamine Regulation Of Cellular Response To Growth Factor Stimulus Negative Regulation Of RNA Biosynthetic Process Regulation Of Cell Communication Regulation Of Signaling Negative Regulation Of Biosynthetic Process Intracellular Signal Transduction Response To Dopamine Positive Regulation Of Autophagy Establishment Of Golgi Localization Innate Immune Response Regulation Of Proteolysis Cellular Response To Manganese Ion Regulation Of MAPK Cascade Negative Regulation Of RNA Metabolic Process Positive Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Progesterone Receptor Signaling Pathway Regulation Of Protein Metabolic Process Negative Regulation Of Macromolecule Metabolic Process Defense Response To Symbiont Negative Regulation Of Nucleobase-containing Compound Metabolic Process Establishment Of Localization In Cell
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