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ZBTB18 and DNMT3B
Number of citations of the paper that reports this interaction (PMID
11350943
)
103
Data Source:
HPRD
(in vitro)
ZBTB18
DNMT3B
Gene Name
zinc finger and BTB domain containing 18
DNA (cytosine-5-)-methyltransferase 3 beta
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Nuclear Chromosome
Nucleus
Nucleoplasm
Microtubule Cytoskeleton
Intercellular Bridge
Nucleus
Nucleoplasm
Nuclear Heterochromatin
Cytoplasm
Intracellular Membrane-bounded Organelle
Molecular Function
DNA Binding
Sequence-specific DNA Binding Transcription Factor Activity
Sequence-specific DNA Binding
Metal Ion Binding
Transcription Corepressor Activity
DNA (cytosine-5-)-methyltransferase Activity
Protein Binding
DNA-methyltransferase Activity
Unmethylated CpG Binding
Metal Ion Binding
DNA (cytosine-5-)-methyltransferase Activity, Acting On CpG Substrates
Biological Process
Negative Regulation Of Transcription From RNA Polymerase II Promoter
In Utero Embryonic Development
Transcription, DNA-templated
Skeletal Muscle Tissue Development
Cerebellum Development
Hippocampus Development
Cerebral Cortex Development
Negative Regulation Of Transcription, DNA-templated
Neuron Development
Homeostasis Of Number Of Cells
Regulation Of Cell Division
Negative Regulation Of Transcription From RNA Polymerase II Promoter
DNA Methylation
Methylation-dependent Chromatin Silencing
Regulation Of Gene Expression By Genetic Imprinting
Response To Ionizing Radiation
DNA Methylation On Cytosine Within A CG Sequence
Gene Expression
Positive Regulation Of Gene Expression
Protein Complex Localization
DNA Methylation On Cytosine
Regulation Of Gene Expression, Epigenetic
Response To Drug
Positive Regulation Of Neuron Differentiation
Negative Regulation Of Gene Expression, Epigenetic
S-adenosylhomocysteine Metabolic Process
S-adenosylmethioninamine Metabolic Process
Positive Regulation Of Histone H3-K4 Methylation
Negative Regulation Of Histone H3-K9 Methylation
Cellular Response To Amino Acid Stimulus
C-5 Methylation Of Cytosine
Pathways
NoRC negatively regulates rRNA expression
Epigenetic regulation of gene expression
Negative epigenetic regulation of rRNA expression
PRC2 methylates histones and DNA
DNA methylation
Drugs
Diseases
GWAS
Inflammatory bowel disease (
23128233
)
Protein-Protein Interactions
7 interactors:
CTBP1
CTBP2
DNMT3A
DNMT3B
PAK1
POMGNT1
TSN
35 interactors:
BAZ2A
CBX1
CBX3
CBX5
CMTM6
DNMT1
DNMT3A
DNMT3L
DUSP23
EED
EZH2
HDAC1
HDAC2
HELLS
KIF4A
MAP1LC3B
MBD4
NCAPG
NEDD8
NRIP1
PAM16
PCYT2
PLEKHJ1
RPS10
SMARCA5
SMC2
SPI1
SUMO1
SUV39H1
TDG
TSC22D1
UBE2I
UBE2W
WARS
ZBTB18
Entrez ID
10472
1789
HPRD ID
12231
04209
Ensembl ID
ENSG00000179456
ENSG00000088305
Uniprot IDs
Q99592
Q9UBC3
PDB IDs
3FLG
3QKJ
Enriched GO Terms of Interacting Partners
?
S-adenosylmethioninamine Metabolic Process
DNA Methylation On Cytosine Within A CG Sequence
C-5 Methylation Of Cytosine
S-adenosylhomocysteine Metabolic Process
Methylation-dependent Chromatin Silencing
DNA Methylation On Cytosine
White Fat Cell Differentiation
Chromatin Modification
Viral Genome Replication
Chromatin Organization
Regulation Of Gene Expression By Genetic Imprinting
Chromatin Silencing
Genetic Imprinting
Regulation Of Transcription From RNA Polymerase II Promoter
Gene Expression
Chromosome Organization
DNA Methylation
Cellular Response To Amino Acid Stimulus
Negative Regulation Of Transcription, DNA-templated
Negative Regulation Of Nucleic Acid-templated Transcription
Negative Regulation Of RNA Biosynthetic Process
Positive Regulation Of Organelle Organization
Positive Regulation Of Histone Modification
Negative Regulation Of Gene Expression, Epigenetic
Cellular Response To Organonitrogen Compound
DNA Modification
Negative Regulation Of Chromosome Organization
Negative Regulation Of Gene Expression
Negative Regulation Of Transcription From RNA Polymerase II Promoter By Histone Modification
Nucleobase-containing Compound Metabolic Process
Negative Regulation Of Biosynthetic Process
Gene Silencing
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Response To Amino Acid
Cellular Nitrogen Compound Metabolic Process
Fat Cell Differentiation
Regulation Of Histone Modification
Negative Regulation Of Cell Proliferation
Nitrogen Compound Metabolic Process
Cellular Response To Acid Chemical
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Hypermethylation Of CpG Island
Response To Organonitrogen Compound
Viral Life Cycle
Negative Regulation Of Cell Proliferation Involved In Contact Inhibition
Positive Regulation Of Retinoic Acid Receptor Signaling Pathway
Regulation Of Chromosome Organization
Regulation Of Gene Expression, Epigenetic
Positive Regulation Of Chromatin Binding
Negative Regulation Of Gene Expression, Epigenetic
Regulation Of Gene Expression, Epigenetic
Negative Regulation Of Transcription, DNA-templated
Negative Regulation Of Nucleic Acid-templated Transcription
Negative Regulation Of RNA Biosynthetic Process
Negative Regulation Of Gene Expression
Negative Regulation Of Biosynthetic Process
Negative Regulation Of Cellular Metabolic Process
DNA Modification
Chromatin Modification
Chromosome Organization
Chromatin Silencing
Chromatin Organization
Gene Silencing
Nucleobase-containing Compound Metabolic Process
DNA Methylation
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Organelle Organization
Cellular Nitrogen Compound Metabolic Process
DNA Metabolic Process
Regulation Of Transcription, DNA-templated
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Regulation Of RNA Metabolic Process
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Nitrogen Compound Metabolic Process
Gene Expression
Regulation Of Gene Expression
Regulation Of Nitrogen Compound Metabolic Process
RNA Biosynthetic Process
Cellular Metabolic Process
Methylation
Transcription, DNA-templated
Histone H3-K9 Modification
Chromatin Remodeling
RNA Metabolic Process
DNA Methylation On Cytosine
Regulation Of Transcription From RNA Polymerase II Promoter
Chromatin Silencing At RDNA
Histone Modification
Peptidyl-lysine Modification
Histone H4 Deacetylation
Cellular Macromolecule Biosynthetic Process
Macromolecule Biosynthetic Process
Rhythmic Process
DNA Packaging
Regulation Of Gene Expression By Genetic Imprinting
Hypermethylation Of CpG Island
C-5 Methylation Of Cytosine
Tagcloud
?
cpg
cues
de
dense
dnmt1
dnmts
enhancers
ensure
ensures
establishment
excluded
guide
lethal
localize
methylated
methylation
methylome
methyltransferase
methyltransferases
novo
nucleosomes
observe
preferential
promoters
pwwp
reflects
setd2
transcribed
Tagcloud (Difference)
?
cpg
cues
de
dense
dnmt1
dnmts
enhancers
ensure
ensures
establishment
excluded
guide
lethal
localize
methylated
methylation
methylome
methyltransferase
methyltransferases
novo
nucleosomes
observe
preferential
promoters
pwwp
reflects
setd2
transcribed
Tagcloud (Intersection)
?