TXLNA and CCDC136

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		TXLNA	CCDC136
Description		taxilin alpha	coiled-coil domain containing 136
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Cytoplasm Cytosol Membrane	Acrosomal Membrane Membrane Cytoplasmic Vesicle
	Molecular Function	Protein Binding Syntaxin Binding	Protein Binding
	Biological Process	Exocytosis B Cell Activation	Acrosome Assembly Spermatogenesis Single Fertilization Cell Differentiation
Pathways		Other interleukin signaling
Drugs
Diseases
GWAS			Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Hypertrophic cardiomyopathy ( 33495596) Hypertrophic cardiomyopathy (MTAG) ( 33495596) Reading disability or specific language impairment (pleiotropy) ( 25065397) Reading disability or specific language impairment adjusted for intelligence quotient (pleiotropy) ( 25065397)
Interacting Genes		95 interacting genes: AXIN2 AZI2 BIN3 BRCA1 BRMS1L BTF3 BTF3L4 CBY2 CCDC112 CCDC136 CCDC146 CCDC196 CCDC33 CCDC57 CCHCR1 CDC5L CDR2 CEBPA CEP44 CEP57 CEP57L1 CEP63 CFAP53 DEUP1 DMAP1 DRC4 DTNB EIF4ENIF1 EPN2 FAM81A FAM9A GOLGA2 GOLGA6A GORASP2 HAUS3 HYPK IKBKG KANK2 KIAA1328 KRT13 KRT15 KRT20 KRT24 KRT31 KRT34 KRT35 KRT36 KRT38 KRT40 KRT75 LCA5 LZTS1 MBIP MCC MEOX1 MEOX2 MIS18A NACA NDC80 NKAPD1 NMI NSMCE2 NUP62 OLIG2 PIAS2 PPFIA1 PPP1R13B PRDM16 PRPF3 RASSF8 RCOR3 RINT1 SIKE1 SLC25A21-AS1 SMARCE1 SNCA SNF8 SORBS3 SREK1 STMN2 STX1A STX1B STX3 STX4 TBC1D1 TCL1A TFIP11 TNIP1 TP53BP2 TTC33 TXLNB USHBP1 UTP14C WASHC1 WASHC3	138 interacting genes: ABT1 AQP1 ATP5PO ATXN1 BARD1 BLOC1S6 BYSL C1orf216 C21orf58 CARD9 CBX8 CCDC120 CCDC13 CCDC146 CCDC185 CCDC187 CCDC6 CCHCR1 CDC5L CDK2AP1 CEP57 CEP57L1 CEP95 COIL CWF19L2 DDX6 DISC1 DTNB DYNC1I2 ENKD1 FAM107A FAM161A FAM161B FAM50B FLYWCH1 GFI1B HAUS1 HDAC4 HGS HMG20A HMG20B HOXB5 ISCU JAKMIP2 JMY JRK KANSL1 KAT5 KIF5B KIFC3 LCA5L LENG1 MAGEB4 MBD1 MBD3L2 MCRS1 MOS NDC80 NDN NEBL NEK6 NME7 NOP53 ODAD3 PDLIM5 PIBF1 PKN1 PKN2 POGZ PPP1R18 PRPF18 PRPF3 PRPF31 PRR35 PSMA1 PSMC5 PSMD9 RAB33A RAB33B RALBP1 RASAL3 RASSF8 SCNM1 SDHAF1 SHFL SMARCA2 SMARCE1 SYT6 TBRG1 TCEA2 TCEANC THAP7 TNNT1 TRAF3IP3 TSGA10 TSGA10IP TSPYL1 TXLNA UBQLN4 UBTFL1 USP2 WT1 ZBTB24 ZBTB38 ZBTB47 ZC2HC1C ZFP1 ZFYVE26 ZNF124 ZNF20 ZNF223 ZNF230 ZNF250 ZNF264 ZNF329 ZNF35 ZNF408 ZNF417 ZNF440 ZNF490 ZNF497 ZNF564 ZNF572 ZNF580 ZNF581 ZNF587 ZNF599 ZNF648 ZNF669 ZNF670 ZNF688 ZNF696 ZNF774 ZNF777 ZNF785 ZNF835 ZNF837 ZSCAN26
Entrez ID		200081	64753
HPRD ID		09408	10887
Ensembl ID		ENSG00000084652	ENSG00000128596
Uniprot IDs		P40222	C9JU31 Q96JN2
PDB IDs
Enriched GO Terms of Interacting Partners?		Structural Constituent Of Skin Epidermis Intermediate Filament Organization Intermediate Filament Cytoskeleton Organization Keratin Filament Intermediate Filament-based Process Organelle Organization Intermediate Filament Supramolecular Fiber Organization Cytoskeleton Structural Molecule Activity Microtubule Organizing Center Organization Protein Binding Cytoskeleton Organization Centriole Assembly Centriole Centrosome Cycle Centriole Replication Epithelial Cell Differentiation Morphogenesis Of An Epithelium Cytoplasm Membraneless Organelle Assembly Negative Regulation Of Protein Localization To Endoplasmic Reticulum SNARE Binding Microtubule-based Process HMG Box Domain Binding SNARE Complex Assembly Organelle Assembly SNAP Receptor Activity Nascent Polypeptide-associated Complex Tissue Morphogenesis SNARE Complex Exocytosis Cell Differentiation Negative Regulation Of Cell Cycle Cytosol Positive Regulation Of Neurotransmitter Secretion Identical Protein Binding Neurotransmitter Transport Regulation Of Cell Cycle Spindle Pole Centrosome Somite Specification De Novo Centriole Assembly Involved In Multi-ciliated Epithelial Cell Differentiation Cellular Developmental Process Vesicle Docking De Novo Centriole Assembly Microtubule Binding Establishment Of Protein Localization Manchette Assembly Regulation Of Cytoskeleton Organization	Regulation Of Transcription By RNA Polymerase II Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Zinc Ion Binding Regulation Of RNA Metabolic Process DNA Binding Nucleus Regulation Of Nucleobase-containing Compound Metabolic Process Protein Binding Regulation Of Primary Metabolic Process Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process Centrosome Regulation Of Macromolecule Metabolic Process DNA-binding Transcription Factor Activity, RNA Polymerase II-specific RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Metal Ion Binding Regulation Of Metabolic Process Cytoskeleton Chromatin Organization Microtubule-based Process Cilium Organization Nuclear Speck Microtubule Binding Spindle Pole Organelle Assembly Nuclear Proteasome Complex Negative Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of RNA Metabolic Process Identical Protein Binding Nucleoplasm Regulation Of Sister Chromatid Segregation Cellular Component Assembly Microtubule Cytoskeleton Organization DNA-binding Transcription Factor Activity Centriole Protein Localization To Nucleoplasm Establishment Of Spindle Orientation Microtubule Double-stranded Methylated DNA Binding Cytosolic Proteasome Complex Centriolar Satellite Regulation Of Chromosome Segregation Regulation Of Protein Sumoylation Non-motile Cilium Assembly Histone Acetyltransferase Complex Ciliary Basal Body Establishment Of Spindle Localization
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