TXLNA and NACA

Number of citations: 55 (PubMedID 21903422)
Data Source: BioGRID (pull down)

		TXLNA	NACA
Name		taxilin alpha	nascent polypeptide associated complex subunit alpha
Structure		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Cytoplasm Cytosol Membrane	Nucleus Cytoplasm Nascent Polypeptide-associated Complex Extracellular Exosome
	Molecular Function	Protein Binding Syntaxin Binding	DNA Binding Transcription Coactivator Activity Protein Binding Unfolded Protein Binding
	Biological Process	Exocytosis B Cell Activation	Negative Regulation Of Transcription By RNA Polymerase II Cardiac Ventricle Development Translation Protein Targeting To Membrane Negative Regulation Of Striated Muscle Cell Apoptotic Process Protein Transport Wound Healing Skeletal Muscle Tissue Regeneration Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Skeletal Muscle Tissue Growth Regulation Of Skeletal Muscle Fiber Development Heart Trabecula Morphogenesis Negative Regulation Of Protein Localization To Endoplasmic Reticulum Positive Regulation Of Cell Proliferation Involved In Heart Morphogenesis
Pathways		Other interleukin signaling	None
GWAS		No GWAS studies recorded	Alanine aminotransferase levels ( 34315874 ) Aspartate aminotransferase levels ( 34315874 ) Asthma ( 31619474 ) Atrial fibrillation ( 29892015 30061737 ) Diastolic blood pressure ( 30224653 ) JT interval ( 29874175 ) QRS duration ( 30012220 )
Interacting Genes		95 interacting genes: AXIN2 AZI2 BIN3 BRCA1 BRMS1L BTF3 BTF3L4 CBY2 CCDC112 CCDC136 CCDC146 CCDC196 CCDC33 CCDC57 CCHCR1 CDC5L CDR2 CEBPA CEP44 CEP57 CEP57L1 CEP63 CFAP53 DEUP1 DMAP1 DRC4 DTNB EIF4ENIF1 EPN2 FAM81A FAM9A GOLGA2 GOLGA6A GORASP2 HAUS3 HYPK IKBKG KANK2 KIAA1328 KRT13 KRT15 KRT20 KRT24 KRT31 KRT34 KRT35 KRT36 KRT38 KRT40 KRT75 LCA5 LZTS1 MBIP MCC MEOX1 MEOX2 MIS18A NACA NDC80 NKAPD1 NMI NSMCE2 NUP62 OLIG2 PIAS2 PPFIA1 PPP1R13B PRDM16 PRPF3 RASSF8 RCOR3 RINT1 SIKE1 SLC25A21-AS1 SMARCE1 SNCA SNF8 SORBS3 SREK1 STMN2 STX1A STX1B STX3 STX4 TBC1D1 TCL1A TFIP11 TNIP1 TP53BP2 TTC33 TXLNB USHBP1 UTP14C WASHC1 WASHC3	17 interacting genes: APLP1 CCDC90B FADD FOS FUNDC2 IGSF21 JUN LRIF1 MDM2 PPP1R18 PTEN SMYD1 SPP1 TBP TXLNA UCHL5 ZHX1
Entrez ID		200081	4666
HPRD ID		09408	03137
Ensembl ID		ENSG00000084652	ENSG00000196531
Uniprot IDs		P40222	E9PAV3 Q13765
PDB IDs		Not available	3LKX 3MCB 3MCE 7QWQ 7QWR 7QWS 8P2K 9F1B 9F1C 9F1D 9FQ0
GO Terms Enriched among Interactors		Structural Constituent Of Skin Epidermis Intermediate Filament Organization Intermediate Filament Cytoskeleton Organization Keratin Filament Intermediate Filament-based Process Organelle Organization Intermediate Filament Supramolecular Fiber Organization Cytoskeleton Structural Molecule Activity Microtubule Organizing Center Organization Protein Binding Cytoskeleton Organization Centriole Assembly Centriole Centrosome Cycle Centriole Replication Epithelial Cell Differentiation Morphogenesis Of An Epithelium Cytoplasm Membraneless Organelle Assembly Negative Regulation Of Protein Localization To Endoplasmic Reticulum SNARE Binding Microtubule-based Process HMG Box Domain Binding SNARE Complex Assembly Organelle Assembly SNAP Receptor Activity Nascent Polypeptide-associated Complex Tissue Morphogenesis SNARE Complex Exocytosis Cell Differentiation Negative Regulation Of Cell Cycle Cytosol Positive Regulation Of Neurotransmitter Secretion Identical Protein Binding Neurotransmitter Transport Regulation Of Cell Cycle Spindle Pole Centrosome Somite Specification De Novo Centriole Assembly Involved In Multi-ciliated Epithelial Cell Differentiation Cellular Developmental Process Vesicle Docking De Novo Centriole Assembly Microtubule Binding Establishment Of Protein Localization Manchette Assembly Regulation Of Cytoskeleton Organization	Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Transcription Factor AP-1 Complex Receptor Serine/threonine Kinase Binding Forebrain Morphogenesis Response To Steroid Hormone Regulation Of Vascular Associated Smooth Muscle Cell Proliferation Regulation Of RNA Metabolic Process Synapse Maturation Regulation Of Nucleobase-containing Compound Metabolic Process RNA Polymerase II Core Promoter Sequence-specific DNA Binding Regulation Of Macromolecule Biosynthetic Process Regulation Of Gene Expression Response To Immobilization Stress Response To Muscle Stretch SMAD Protein Signal Transduction R-SMAD Binding Negative Regulation Of Neuron Projection Development Regulation Of Primary Metabolic Process Regulation Of Smooth Muscle Cell Proliferation Regulation Of Proteolysis Alpha-2B Adrenergic Receptor Binding Developmental Process Response To Mechanical Stimulus Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Medium-term Memory Integrated Stress Response Signaling Cellular Response To Prolactin RNA Polymerase II-specific DNA-binding Transcription Factor Binding Enzyme Binding Positive Regulation Of Vascular Associated Smooth Muscle Cell Proliferation Regulation Of Ubiquitin-dependent Protein Catabolic Process Response To Formaldehyde Cellular Response To Vitamin B1 Response To Cocaine Negative Regulation Of Cell Projection Organization Negative Regulation Of Synaptic Vesicle Clustering Negative Regulation Of Collateral Sprouting Of Intact Axon In Response To Injury Positive Regulation Of CD8-positive, Alpha-beta Cytotoxic T Cell Extravasation Positive Regulation Of Proteolysis Positive Regulation Of RNA Metabolic Process Regulation Of Macromolecule Metabolic Process Negative Regulation Of Axonogenesis Cell Death Apoptotic Process Cytosolic MRNA Polyadenylation Alpha-2C Adrenergic Receptor Binding Animal Organ Development Programmed Cell Death