CDR2 and COX5B

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		CDR2	COX5B
Description		cerebellar degeneration related protein 2	cytochrome c oxidase subunit 5B
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm	Mitochondrion Mitochondrial Envelope Mitochondrial Inner Membrane Membrane Mitochondrial Membrane Respiratory Chain Complex IV
	Molecular Function	Protein Binding	Cytochrome-c Oxidase Activity Protein Binding Metal Ion Binding
	Biological Process		Oxidative Phosphorylation Mitochondrial Electron Transport, Cytochrome C To Oxygen Respiratory Gaseous Exchange By Respiratory System Cellular Respiration Proton Transmembrane Transport
Pathways			TP53 Regulates Metabolic Genes Respiratory electron transport Cytoprotection by HMOX1 Mitochondrial protein degradation Complex IV assembly
Drugs			Cholic Acid N-Formylmethionine
Diseases
GWAS		Femur bone mineral density x serum urate levels interaction ( 34046847)	Bipolar disorder ( 31043756) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		76 interacting genes: AMOTL2 ANKRD36BP1 AQP1 ARNT2 BEX2 C1orf216 C4orf46 CATSPERT CCDC120 CCDC13 CCDC146 CCDC187 CCDC87 CCHCR1 CDC20 CEP57L1 CHIC2 COX5B DRC12 DRC4 EIF4E2 ENKD1 FAM110A FAM161A FAM50B FAM90A1 FXR1 FZR1 GEM GMPPA HAUS1 HDAC4 HGS KANSL1 KIF5B KIFC3 LENG1 LIN37 MICALL2 MKKS MNS1 MORF4L2 MRPL28 NDN NTAQ1 OAZ2 PKN1 PRKAA2 PRPF18 PSMA1 RCOR3 RSPH14 RUNX1T1 SCNM1 SH2D4A SMARCD1 SMARCE1 TBC1D22B TCHP TEAD4 TEX28 TMCC2 TRIM23 TRIML2 TSC1 TSGA10IP TTC23 TTR TXLNA TXLNB UBTFL1 ZGPAT ZMAT2 ZNF250 ZNF35 ZNF417	35 interacting genes: AR ARID5A BHLHE40 CDC42EP2 CDR2 CDR2L DOK3 FAM228A FLOT1 GOLGA2 IHO1 KRT15 KRT27 KRT31 KRT33B LSM4 MCCD1 MID2 NUDT5 OIP5 PLEKHF2 PNMA1 PRDM6 PRKAR1B PRR22 RBM48 SAXO4 SLAIN1 TASOR2 TEX12 TFIP11 TRAF1 TRIM23 TRIM27 VPS28
Entrez ID		1039	1329
HPRD ID		06681	00467
Ensembl ID		ENSG00000140743	ENSG00000135940
Uniprot IDs		Q01850	A0A384NL93 P10606
PDB IDs			5Z62
Enriched GO Terms of Interacting Partners?		Protein Binding Centrosome Cytoskeleton Ciliary Basal Body Microtubule Cytoskeleton Organization Microtubule-based Process Motile Cilium Cytoplasm Positive Regulation Of Anaphase-promoting Complex-dependent Catabolic Process Microtubule Binding Cilium Regulation Of Anaphase-promoting Complex-dependent Catabolic Process Positive Regulation Of Ubiquitin Protein Ligase Activity Cytoskeleton Organization Cell Projection Cilium Organization Polymeric Cytoskeletal Fiber	Structural Constituent Of Skin Epidermis Intermediate Filament Cytoskeleton Organization Structural Molecule Activity Keratin Filament Intermediate Filament-based Process Intermediate Filament Organization Supramolecular Fiber Organization Organelle Organization Intermediate Filament Cellular Response To Estrogen Stimulus Morphogenesis Of An Epithelium Cytoskeleton Suppression Of Viral Release By Host Negative Regulation Of Viral Transcription Cytoskeleton Organization Regulation Of Viral Transcription
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