CDR2 and C4orf46

Number of citations of the paper that reports this interaction (PubMedID 33961781)
97

Data Source:
BioGRID (two hybrid, affinity chromatography technology, two hybrid, affinity chromatography technology)

		CDR2	C4orf46
Description		cerebellar degeneration related protein 2	chromosome 4 open reading frame 46
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm	Cytoplasm Cytosol
	Molecular Function	Protein Binding	Protein Binding
	Biological Process
Pathways
Drugs
Diseases
GWAS		Femur bone mineral density x serum urate levels interaction ( 34046847)
Interacting Genes		76 interacting genes: AMOTL2 ANKRD36BP1 AQP1 ARNT2 BEX2 C1orf216 C4orf46 CATSPERT CCDC120 CCDC13 CCDC146 CCDC187 CCDC87 CCHCR1 CDC20 CEP57L1 CHIC2 COX5B DRC12 DRC4 EIF4E2 ENKD1 FAM110A FAM161A FAM50B FAM90A1 FXR1 FZR1 GEM GMPPA HAUS1 HDAC4 HGS KANSL1 KIF5B KIFC3 LENG1 LIN37 MICALL2 MKKS MNS1 MORF4L2 MRPL28 NDN NTAQ1 OAZ2 PKN1 PRKAA2 PRPF18 PSMA1 RCOR3 RSPH14 RUNX1T1 SCNM1 SH2D4A SMARCD1 SMARCE1 TBC1D22B TCHP TEAD4 TEX28 TMCC2 TRIM23 TRIML2 TSC1 TSGA10IP TTC23 TTR TXLNA TXLNB UBTFL1 ZGPAT ZMAT2 ZNF250 ZNF35 ZNF417	10 interacting genes: APP BLOC1S6 CDR2 CDR2L HSF2BP HUS1 KXD1 PICK1 SRPK2 TFPT
Entrez ID		1039	201725
HPRD ID		06681	17319
Ensembl ID		ENSG00000140743	ENSG00000205208
Uniprot IDs		Q01850	Q504U0
PDB IDs
Enriched GO Terms of Interacting Partners?		Protein Binding Centrosome Cytoskeleton Ciliary Basal Body Microtubule Cytoskeleton Organization Microtubule-based Process Motile Cilium Cytoplasm Positive Regulation Of Anaphase-promoting Complex-dependent Catabolic Process Microtubule Binding Cilium Regulation Of Anaphase-promoting Complex-dependent Catabolic Process Positive Regulation Of Ubiquitin Protein Ligase Activity Cytoskeleton Organization Cell Projection Cilium Organization Polymeric Cytoskeletal Fiber	Cytoskeleton-dependent Intracellular Transport Transport Along Microtubule Microtubule-based Transport Organelle Transport Along Microtubule BLOC-1 Complex Microtubule-based Movement Positive Regulation Of Receptor Internalization Amyloid-beta Complex Presynapse Growth Cone Lamellipodium Neuron Projection Organization Intracellular Transport Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Receptor-mediated Endocytosis Bradykinin Biosynthetic Process Vesicle Cytoskeletal Trafficking Vesicle Transport Along Microtubule Establishment Of Organelle Localization Circadian Sleep/wake Cycle Glial Cell Development Positive Regulation Of Neuron Apoptotic Process G Protein-coupled Receptor Binding Microtubule-based Process Regulation Of Receptor Internalization Axo-dendritic Transport Cellular Localization Establishment Of Localization In Cell Acetylcholine Receptor Activator Activity Lipoprotein Particle Positive Regulation Of Protein Import Meiotic DNA Integrity Checkpoint Signaling PTB Domain Binding Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Endothelin Production Growth Cone Filopodium Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Telomere Maintenance Intracellular Nitric Oxide Homeostasis Establishment Of Vesicle Localization Golgi To Secretory Granule Transport Trans-Golgi Network Membrane Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Cellular Response To Norepinephrine Stimulus
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