IRF2BP1 and JDP2

Number of citations of the paper that reports this interaction (PMID 18671972)
7

Data Source:
BioGRID (pull down)

		IRF2BP1	JDP2
Gene Name		interferon regulatory factor 2 binding protein 1	Jun dimerization protein 2
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Aggresome Intracellular Membrane-bounded Organelle	Nucleus Nucleoplasm
	Molecular Function	Protein Binding Ligase Activity Metal Ion Binding	Chromatin Binding Double-stranded DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Protein Binding Sequence-specific DNA Binding Protein Heterodimerization Activity
	Biological Process	Transcription, DNA-templated Regulation Of Transcription, DNA-templated	Negative Regulation Of Transcription From RNA Polymerase II Promoter Transcription, DNA-templated Positive Regulation Of Histone Deacetylation Negative Regulation Of Fat Cell Differentiation
Pathways
Drugs
Diseases
GWAS			Obesity-related traits ( 23251661) Periodontal microbiota ( 22699663)
Protein-Protein Interactions		7 interactors: ATF2 IRF2 IRF9 JDP2 PCBD2 SMAD1 TGIF1	18 interactors: ATF2 CREBBP EP300 GTF2H1 HDAC1 HDAC4 HDAC5 HDAC6 IRF2BP1 JUN JUNB JUND KAT2B MAPK14 MAPK8 MAPK9 PGR SNW1
Entrez ID		26145	122953
HPRD ID		17159	16360
Ensembl ID		ENSG00000170604	ENSG00000140044
Uniprot IDs		Q8IU81	Q8WYK2
PDB IDs
Enriched GO Terms of Interacting Partners?		Transcription From RNA Polymerase II Promoter Transcription, DNA-templated Regulation Of Transcription, DNA-templated RNA Biosynthetic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process RNA Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Gene Expression Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Positive Regulation Of Cellular Metabolic Process Negative Regulation Of Gene Expression Positive Regulation Of Transcription, DNA-templated Defense Response Nucleobase-containing Compound Metabolic Process Regulation Of Metabolic Process Type I Interferon Signaling Pathway Cellular Response To Type I Interferon Response To Type I Interferon Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Interferon-gamma-mediated Signaling Pathway Positive Regulation Of Transforming Growth Factor Beta2 Production Positive Regulation Of Cellular Biosynthetic Process Transforming Growth Factor Beta Receptor Signaling Pathway Cellular Response To Interferon-gamma Positive Regulation Of Metabolic Process Response To Interferon-gamma Negative Regulation Of Transcription From RNA Polymerase II Promoter Cellular Response To Organic Substance Cellular Response To Transforming Growth Factor Beta Stimulus Innate Immune Response Response To Transforming Growth Factor Beta Primary MiRNA Processing MAPK Cascade Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Connective Tissue Development Osteoblast Fate Commitment Regulation Of Transforming Growth Factor Beta2 Production Positive Regulation Of Transcription From RNA Polymerase II Promoter Tetrahydrobiopterin Biosynthetic Process	Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Cellular Biosynthetic Process Transcription, DNA-templated RNA Biosynthetic Process Positive Regulation Of Cellular Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Positive Regulation Of Metabolic Process Regulation Of RNA Metabolic Process Regulation Of Gene Expression Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Nitrogen Compound Metabolic Process RNA Metabolic Process Gene Expression Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Transcription Initiation From RNA Polymerase II Promoter Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Response To Organic Substance Histone H3-K9 Modification Transcription From RNA Polymerase II Promoter Histone Modification DNA-templated Transcription, Initiation N-terminal Peptidyl-lysine Acetylation Nucleobase-containing Compound Metabolic Process Toll-like Receptor 5 Signaling Pathway Toll-like Receptor 10 Signaling Pathway Toll-like Receptor TLR6:TLR2 Signaling Pathway Toll-like Receptor TLR1:TLR2 Signaling Pathway Notch Signaling Pathway Cellular Response To Organic Substance Toll-like Receptor 2 Signaling Pathway Toll-like Receptor 9 Signaling Pathway Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process TRIF-dependent Toll-like Receptor Signaling Pathway Regulation Of Metabolic Process Response To Abiotic Stimulus MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway Rhythmic Process Regulation Of Viral Transcription Cellular Nitrogen Compound Metabolic Process MyD88-dependent Toll-like Receptor Signaling Pathway Histone H4 Deacetylation
Tagcloud ?		abundance collection colorectal dataset dissected front give healing igf1 immunohistochemical individually insights invasion knockout largest lymph lymphatic mx1 node nonmetastatic overexpressed phenotypes proteome quantified representing resolution validation wilcoxon wound	ap basal cloned contains dimerization direct extension feedback flanking given inhibits interestingly investigate jun key link loop nt oncogenic p53 primer promoter region repressed repressor start suppressor transcription transcriptional
Tagcloud (Difference) ?		abundance collection colorectal dataset dissected front give healing igf1 immunohistochemical individually insights invasion knockout largest lymph lymphatic mx1 node nonmetastatic overexpressed phenotypes proteome quantified representing resolution validation wilcoxon wound	ap basal cloned contains dimerization direct extension feedback flanking given inhibits interestingly investigate jun key link loop nt oncogenic p53 primer promoter region repressed repressor start suppressor transcription transcriptional
Tagcloud (Intersection) ?