KIF4A and TTF2

Number of citations of the paper that reports this interaction (PMID 12927788)
7

Data Source:
HPRD (in vivo)

		KIF4A	TTF2
Gene Name		kinesin family member 4A	transcription termination factor, RNA polymerase II
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Chromosome Cytoplasm Cytosol Kinesin Complex Spindle Microtubule Membrane Nuclear Matrix Midbody	Spliceosomal Complex Cytoplasm Transcription Elongation Factor Complex
	Molecular Function	DNA Binding Microtubule Motor Activity Protein Binding ATP Binding Microtubule Binding ATP-dependent Microtubule Motor Activity, Plus-end-directed ATPase Activity	DNA Binding Protein Binding ATP Binding ATP-dependent Helicase Activity DNA-dependent ATPase Activity Zinc Ion Binding
	Biological Process	Mitotic Cytokinesis Organelle Organization Microtubule-based Movement Axon Guidance Blood Coagulation Anterograde Axon Cargo Transport Metabolic Process Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Mitotic Spindle Midzone Assembly	DNA-templated Transcription, Termination Regulation Of Transcription, DNA-templated Termination Of RNA Polymerase II Transcription MRNA Processing RNA Splicing
Pathways		Axon guidance MHC class II antigen presentation Kinesins L1CAM interactions Recycling pathway of L1 Factors involved in megakaryocyte development and platelet production Adaptive Immune System
Drugs
Diseases
GWAS
Protein-Protein Interactions		5 interactors: APP DNMT3B HMG20B PRC1 TTF2	22 interactors: CDC5L CDKL3 CLPB DCP1A DR1 DRAP1 HINFP HNRNPA1 HNRNPA2B1 KIF4A MATR3 MYB MYBL2 NVL PDCD6IP PRDX4 SKIL SMAD1 SMAD7 TACC3 TNIP1 ZSCAN1
Entrez ID		24137	8458
HPRD ID		06606	05280
Ensembl ID		ENSG00000090889
Uniprot IDs		O95239 Q59HG1	Q9UNY4
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Neuron Differentiation Regulation Of Neurogenesis Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Cellular Protein Metabolic Process Synaptic Growth At Neuromuscular Junction Pharynx Development Regulation Of Cell Development Negative Regulation Of Protein Metabolic Process Collateral Sprouting In Absence Of Injury S-adenosylmethioninamine Metabolic Process DNA Methylation On Cytosine Within A CG Sequence Collateral Sprouting Negative Regulation Of Protein Sumoylation Axon Midline Choice Point Recognition Cellular Modified Amino Acid Metabolic Process Smooth Endoplasmic Reticulum Calcium Ion Homeostasis C-5 Methylation Of Cytosine S-adenosylhomocysteine Metabolic Process Axon Choice Point Recognition Soft Palate Development Mitotic Spindle Elongation Methylation-dependent Chromatin Silencing Positive Regulation Of Neuron Differentiation Neuron Remodeling Gene Expression Hard Palate Development Positive Regulation Of Gene Expression Generation Of Neurons Negative Regulation Of Histone H3-K9 Methylation DNA Methylation On Cytosine Regulation Of Cell Differentiation Positive Regulation Of Neurogenesis Blood Coagulation MRNA Processing Neurogenesis Hemostasis Positive Regulation Of Histone H3-K4 Methylation Response To Radiation Regulation Of Protein Sumoylation Cellular Copper Ion Homeostasis Thyroid Hormone Generation Protein Complex Localization Negative Regulation Of Histone Methylation Regulation Of Transcription From RNA Polymerase II Promoter System Development Positive Regulation Of Cell Development Regulation Of Transcription, DNA-templated Copper Ion Homeostasis Suckling Behavior Regulation Of Nucleic Acid-templated Transcription	Gene Expression Regulation Of Transcription From RNA Polymerase II Promoter RNA Metabolic Process Heterocycle Metabolic Process Transcription, DNA-templated Negative Regulation Of Gene Expression RNA Biosynthetic Process Nucleobase-containing Compound Metabolic Process Nitrogen Compound Metabolic Process Cell Cycle Process Cellular Aromatic Compound Metabolic Process Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Cellular Macromolecule Biosynthetic Process Regulation Of RNA Metabolic Process Macromolecule Biosynthetic Process Transcription From RNA Polymerase II Promoter Negative Regulation Of Biosynthetic Process Cell Cycle Regulation Of Cell Cycle Regulation Of Gene Expression Cellular Metabolic Process Mitotic Spindle Assembly Regulation Of Nitrogen Compound Metabolic Process Spindle Organization Negative Regulation Of Cellular Metabolic Process Transforming Growth Factor Beta Receptor Signaling Pathway Positive Regulation Of Cell Morphogenesis Involved In Differentiation Positive Regulation Of Dendrite Morphogenesis Cellular Response To Transforming Growth Factor Beta Stimulus Response To Transforming Growth Factor Beta Positive Regulation Of Transcription, DNA-templated Regulation Of Cell Morphogenesis Biosynthetic Process Mitotic Spindle Organization Positive Regulation Of Neuron Projection Development MRNA Metabolic Process MRNA Splicing, Via Spliceosome Negative Regulation Of Male Germ Cell Proliferation Modulation By Symbiont Of Host I-kappaB Kinase/NF-kappaB Cascade Response To Stress RNA Splicing, Via Transesterification Reactions Positive Regulation Of Dendrite Development Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway
Tagcloud ?		aba achieved adp aminobenzamide apoptosis blot cleaved cytometry doxorubicin elevated fragments inhibiting kinesin manners mb mcf mda par parp poly polymerase profound quantitated reduce ribose slightly super upregulation	away bidirectional coimmunoprecipitate cotranscriptional dcp1a dcp2 decapping edc3 elongation ends exonuclease facilitates localize nascent pause paused peaks pol premature productive redistribution seq shifted spt5 termination torpedo tss tsss xrn2
Tagcloud (Difference) ?		aba achieved adp aminobenzamide apoptosis blot cleaved cytometry doxorubicin elevated fragments inhibiting kinesin manners mb mcf mda par parp poly polymerase profound quantitated reduce ribose slightly super upregulation	away bidirectional coimmunoprecipitate cotranscriptional dcp1a dcp2 decapping edc3 elongation ends exonuclease facilitates localize nascent pause paused peaks pol premature productive redistribution seq shifted spt5 termination torpedo tss tsss xrn2
Tagcloud (Intersection) ?