TRDN and PTPRN

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		TRDN	PTPRN
Description		triadin	protein tyrosine phosphatase receptor type N
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Endoplasmic Reticulum Cytosol Plasma Membrane Junctional Sarcoplasmic Reticulum Membrane Membrane Sarcoplasmic Reticulum Junctional Membrane Complex Sarcoplasmic Reticulum Membrane Sarcoplasmic Reticulum Lumen	Nucleus Endosome Golgi Apparatus Plasma Membrane Synaptic Vesicle Membrane Secretory Granule Axon Transport Vesicle Membrane Cytoplasmic Vesicle Cell Projection Neuronal Cell Body Perikaryon Axon Terminus Synapse
	Molecular Function	Signaling Receptor Binding Protein Binding Protein-macromolecule Adaptor Activity Transmembrane Transporter Binding	Protein Tyrosine Phosphatase Activity Protein Binding Transcription Factor Binding Spectrin Binding Ubiquitin-like Protein Ligase Binding
	Biological Process	Intracellular Calcium Ion Homeostasis Muscle Contraction Response To Bacterium Regulation Of Cell Communication By Electrical Coupling Regulation Of Release Of Sequestered Calcium Ion Into Cytosol By Sarcoplasmic Reticulum Regulation Of Cardiac Muscle Contraction By Regulation Of The Release Of Sequestered Calcium Ion Release Of Sequestered Calcium Ion Into Cytosol By Sarcoplasmic Reticulum Cytoplasmic Microtubule Organization Regulation Of Sequestering Of Calcium Ion Establishment Of Localization In Cell Heart Contraction Regulation Of Cardiac Muscle Cell Membrane Potential Endoplasmic Reticulum Membrane Organization Positive Regulation Of Cell Communication By Electrical Coupling Involved In Cardiac Conduction	Response To Reactive Oxygen Species Luteinization Insulin Secretion Insulin Secretion Involved In Cellular Response To Glucose Stimulus Positive Regulation Of Transcription By RNA Polymerase II Regulation Of Secretion Positive Regulation Of Type B Pancreatic Cell Proliferation Dense Core Granule Maturation
Pathways		Stimuli-sensing channels Ion homeostasis
Drugs
Diseases
GWAS		Asthma exacerbations in inhaled corticosteroid treatment ( 30697902) Borderline personality disorder ( 28632202) Cerebral amyloid deposition in APOEe4 non-carriers (PET imaging) ( 26252872) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Hypertrophic cardiomyopathy (sarcomere negative) ( 33495597) Intraocular pressure ( 30591961) Metabolite levels ( 23823483) Nickel levels ( 26025379) Night sleep phenotypes ( 27126917) Post bronchodilator FEV1 ( 26634245)	High light scatter reticulocyte count ( 27863252) High light scatter reticulocyte percentage of red cells ( 27863252) Mean reticulocyte volume ( 32888494)
Interacting Genes		10 interacting genes: ASPH CALM1 CASQ1 CASQ2 HRC KCNE4 PPIB PTPRN RYR1 SOCS3	19 interacting genes: CAPN2 CCDC134 CLN8 GJA8 GPR152 MADD MAL NOS1 PLP1 PPIA PTPRS PTPRT SNTB2 SNX19 SPTBN4 TIMMDC1 TMEM80 TRDN UBQLN4
Entrez ID		10345	5798
HPRD ID		04474	03466
Ensembl ID		ENSG00000186439	ENSG00000054356
Uniprot IDs		A0A590UJV0 H9ME53 Q13061 Q8IVK2	Q16849 Q96IA0
PDB IDs			2I1Y 2QT7 3N01 3N4W 3NG8 3NP5
Enriched GO Terms of Interacting Partners?		Sarcoplasmic Reticulum Lumen Regulation Of Release Of Sequestered Calcium Ion Into Cytosol By Sarcoplasmic Reticulum Regulation Of Sequestering Of Calcium Ion Regulation Of Cell Communication By Electrical Coupling Calcium-mediated Signaling Sarcoplasmic Reticulum Regulation Of Release Of Sequestered Calcium Ion Into Cytosol Regulation Of Cardiac Muscle Contraction By Regulation Of The Release Of Sequestered Calcium Ion Calcium Channel Complex Regulation Of Striated Muscle Contraction Regulation Of Cardiac Muscle Contraction By Calcium Ion Signaling Sarcoplasmic Reticulum Membrane Regulation Of Calcium Ion Transmembrane Transport Junctional Sarcoplasmic Reticulum Membrane Regulation Of Muscle Contraction Regulation Of Heart Contraction Detection Of Calcium Ion Regulation Of Calcium Ion Transport Regulation Of Cardiac Muscle Contraction Regulation Of Muscle System Process Regulation Of Blood Circulation Smooth Endoplasmic Reticulum Regulation Of Monoatomic Cation Transmembrane Transport Regulation Of System Process Regulation Of Heart Rate Regulation Of Monoatomic Ion Transmembrane Transport Calcium Ion Binding Regulation Of Metal Ion Transport Response To Calcium Ion Z Disc Transmembrane Transporter Binding Regulation Of Monoatomic Ion Transport Terminal Cisterna Intracellular Signaling Cassette Intracellular Calcium Ion Homeostasis Muscle Contraction Regulation Of Cytosolic Calcium Ion Concentration Positive Regulation Of Store-operated Calcium Channel Activity Calcium Ion Homeostasis Muscle System Process Intracellular Signal Transduction Regulation Of Monoatomic Ion Transmembrane Transporter Activity Regulation Of Transmembrane Transporter Activity Cellular Response To Caffeine Regulation Of Cell Communication By Electrical Coupling Involved In Cardiac Conduction Cellular Response To Purine-containing Compound Response To Metal Ion Response To Caffeine Detection Of Chemical Stimulus Intracellular Monoatomic Cation Homeostasis	Membrane Structural Constituent Of Myelin Sheath Central Nervous System Myelination
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?