TRDN and ASPH

Number of citations of the paper that reports this interaction (PMID 9287354)
99

Data Source:
HPRD (in vivo, in vitro)

		TRDN	ASPH
Gene Name		triadin	aspartate beta-hydroxylase
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Endoplasmic Reticulum Plasma Membrane Voltage-gated Calcium Channel Complex Junctional Sarcoplasmic Reticulum Membrane Integral Component Of Membrane Sarcoplasmic Reticulum Junctional Membrane Complex Sarcoplasmic Reticulum Membrane Sarcoplasmic Reticulum Lumen Calcium Channel Complex	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Plasma Membrane Junctional Sarcoplasmic Reticulum Membrane Integral Component Of Membrane Integral Component Of Endoplasmic Reticulum Membrane Cortical Endoplasmic Reticulum Sarcoplasmic Reticulum Membrane Sarcoplasmic Reticulum Lumen Calcium Channel Complex
	Molecular Function	Receptor Binding Protein Binding Protein Binding, Bridging Protein Homodimerization Activity Ion Channel Binding	Peptide-aspartate Beta-dioxygenase Activity Structural Molecule Activity Calcium Ion Binding Protein Binding Structural Constituent Of Muscle Electron Carrier Activity Ion Channel Binding
	Biological Process	Cellular Calcium Ion Homeostasis Muscle Contraction Regulation Of Cell Communication By Electrical Coupling Regulation Of Release Of Sequestered Calcium Ion Into Cytosol By Sarcoplasmic Reticulum Release Of Sequestered Calcium Ion Into Cytosol By Sarcoplasmic Reticulum Cytoplasmic Microtubule Organization Ion Transmembrane Transport Regulation Of Release Of Sequestered Calcium Ion Into Cytosol Transmembrane Transport Heart Contraction Negative Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Positive Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Regulation Of Cardiac Muscle Cell Membrane Potential Endoplasmic Reticulum Membrane Organization Positive Regulation Of Cell Communication By Electrical Coupling Involved In Cardiac Conduction	Detection Of Calcium Ion Muscle Contraction Pattern Specification Process Negative Regulation Of Cell Proliferation Positive Regulation Of Calcium Ion Transport Into Cytosol Regulation Of Cell Communication By Electrical Coupling Regulation Of Release Of Sequestered Calcium Ion Into Cytosol By Sarcoplasmic Reticulum Regulation Of Cardiac Muscle Contraction By Regulation Of The Release Of Sequestered Calcium Ion Regulation Of Inositol 1,4,5-trisphosphate-sensitive Calcium-release Channel Activity Regulation Of Protein Stability Activation Of Store-operated Calcium Channel Activity Response To ATP Limb Morphogenesis Peptidyl-aspartic Acid Hydroxylation Positive Regulation Of Proteolysis Positive Regulation Of Transcription, DNA-templated Oxidation-reduction Process Palate Development Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Positive Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Face Morphogenesis Calcium Ion Transmembrane Transport Cellular Response To Calcium Ion Positive Regulation Of Intracellular Protein Transport Activation Of Cysteine-type Endopeptidase Activity Regulation Of Protein Depolymerization
Pathways		Ion channel transport Stimuli-sensing channels
Drugs			L-Aspartic Acid Succinic acid
Diseases
GWAS
Protein-Protein Interactions		5 interactors: ASPH CALM1 CASQ2 HRC RYR1	3 interactors: APP ASNA1 TRDN
Entrez ID		10345	444
HPRD ID		04474	08996
Ensembl ID		ENSG00000186439	ENSG00000198363
Uniprot IDs		H9ME53 Q13061 Q68D40 Q8IVK2	B4DQ07 B7ZM96 Q12797
PDB IDs			3RCQ
Enriched GO Terms of Interacting Partners?		Regulation Of Cell Communication By Electrical Coupling Regulation Of Cardiac Muscle Contraction By Regulation Of The Release Of Sequestered Calcium Ion Regulation Of Cardiac Muscle Contraction By Calcium Ion Signaling Regulation Of Release Of Sequestered Calcium Ion Into Cytosol By Sarcoplasmic Reticulum Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Regulation Of Ion Homeostasis Muscle Contraction Muscle System Process Regulation Of Calcium Ion Transmembrane Transport Regulation Of Calcium Ion Transmembrane Transporter Activity Regulation Of Release Of Sequestered Calcium Ion Into Cytosol Regulation Of Cation Channel Activity Regulation Of Cardiac Muscle Contraction Regulation Of Calcium Ion Transport Into Cytosol Detection Of Calcium Ion Regulation Of Striated Muscle Contraction Calcium-mediated Signaling Regulation Of Ion Transmembrane Transport Second-messenger-mediated Signaling Regulation Of Ion Transmembrane Transporter Activity Regulation Of Transmembrane Transporter Activity Regulation Of Muscle Contraction Regulation Of Heart Contraction Regulation Of Ion Transport Regulation Of Calcium Ion Transport Regulation Of Heart Rate Regulation Of Cell Communication By Electrical Coupling Involved In Cardiac Conduction Regulation Of Intracellular Transport Positive Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Response To Calcium Ion Negative Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Cellular Response To Caffeine Response To Purine-containing Compound Negative Regulation Of Calcium Ion Transmembrane Transporter Activity Negative Regulation Of Cation Channel Activity Response To Organonitrogen Compound Positive Regulation Of Calcium Ion Transmembrane Transporter Activity Response To Organic Cyclic Compound Response To Caffeine Regulation Of Cellular Localization Positive Regulation Of Cation Channel Activity Cellular Calcium Ion Homeostasis Calcium Ion Homeostasis Response To Metal Ion Cellular Response To Alkaloid Negative Regulation Of Transporter Activity Negative Regulation Of Calcium Ion Transport Negative Regulation Of Ion Transmembrane Transport Detection Of Chemical Stimulus Positive Regulation Of Ion Transmembrane Transporter Activity	Endoplasmic Reticulum Organization Positive Regulation Of Cell Communication By Electrical Coupling Involved In Cardiac Conduction Endoplasmic Reticulum Membrane Organization Synaptic Growth At Neuromuscular Junction Collateral Sprouting In Absence Of Injury Cellular Calcium Ion Homeostasis Calcium Ion Homeostasis Collateral Sprouting Axon Midline Choice Point Recognition Negative Regulation Of Release Of Sequestered Calcium Ion Into Cytosol Positive Regulation Of Cell Communication By Electrical Coupling Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Regulation Of Cell Communication By Electrical Coupling Involved In Cardiac Conduction Axon Choice Point Recognition Release Of Sequestered Calcium Ion Into Cytosol By Sarcoplasmic Reticulum Cellular Metal Ion Homeostasis Protein Insertion Into ER Membrane Positive Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Endomembrane System Organization Regulation Of Cardiac Muscle Cell Membrane Potential Negative Regulation Of Calcium Ion Transport Into Cytosol Cellular Cation Homeostasis Cellular Ion Homeostasis Cellular Localization Neuron Remodeling Metal Ion Homeostasis Negative Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Sarcoplasmic Reticulum Calcium Ion Transport Cellular Chemical Homeostasis Regulation Of Cell Communication By Electrical Coupling Ion Homeostasis Negative Regulation Of Calcium Ion Transmembrane Transporter Activity Cellular Copper Ion Homeostasis Protein Insertion Into Membrane Negative Regulation Of Cation Channel Activity Cellular Homeostasis Copper Ion Homeostasis Suckling Behavior Regulation Of Release Of Sequestered Calcium Ion Into Cytosol By Sarcoplasmic Reticulum Positive Regulation Of Calcium Ion Transmembrane Transporter Activity Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Microtubule-based Process Positive Regulation Of Release Of Sequestered Calcium Ion Into Cytosol Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Neuron Maturation MRNA Polyadenylation Regulation Of Epidermal Growth Factor-activated Receptor Activity Membrane Organization Chemical Homeostasis Positive Regulation Of Cation Channel Activity
Tagcloud ?			3a 3b 5d 6a 6b b3ylp chelate chme cyano dihalodiplatinum diplatinum emitters formulae halide isopropyl lantern maxima paddle phosphorescence phosphorescent photoemissive pop pt pyrophosphite sigma tddft tunable wheel xmmct
Tagcloud (Difference) ?			3a 3b 5d 6a 6b b3ylp chelate chme cyano dihalodiplatinum diplatinum emitters formulae halide isopropyl lantern maxima paddle phosphorescence phosphorescent photoemissive pop pt pyrophosphite sigma tddft tunable wheel xmmct
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