GOLM2 and SOD3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		GOLM2	SOD3
Description		golgi membrane protein 2	superoxide dismutase 3
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Apparatus Membrane	Extracellular Region Extracellular Space Golgi Apparatus Golgi Lumen Extracellular Exosome
	Molecular Function		Superoxide Dismutase Activity Copper Ion Binding Protein Binding Heparin Binding Antioxidant Activity Oxidoreductase Activity Metal Ion Binding Molecular Adaptor Activity
	Biological Process		Response To Hypoxia Superoxide Metabolic Process Removal Of Superoxide Radicals
Pathways			Detoxification of Reactive Oxygen Species Detoxification of Reactive Oxygen Species NFE2L2 regulating anti-oxidant/detoxification enzymes
Drugs			Benzoyl peroxide
Diseases
GWAS			Blood protein levels ( 30072576) Major depressive disorder ( 23377640)
Interacting Genes		17 interacting genes: APP B3GNT7 C3orf52 EMD GOLPH3 GOLPH3L GSK3B LRP10 NXPE3 RNASE12 SOD3 STX1A STX6 TMEM201 TMEM42 TRAF3IP3 VDR	9 interacting genes: ASPH FBLN5 GOLM2 KCNIP1 KCNIP3 SGTA SGTB UBQLN1 UBQLN2
Entrez ID		113201	6649
HPRD ID		11018	01708
Ensembl ID		ENSG00000166734	ENSG00000109610
Uniprot IDs		Q6P4E1	A0A140VJU8 P08294
PDB IDs			2JLP
Enriched GO Terms of Interacting Partners?		Regulation Of Protein Transport Positive Regulation Of Protein Transport Membrane Organization Protein Targeting To Golgi Apparatus Golgi Vesicle Budding Cargo Adaptor Activity Regulation Of Establishment Of Protein Localization Positive Regulation Of Establishment Of Protein Localization Regulation Of Protein Localization Cortical Endoplasmic Reticulum Golgi Cisterna Positive Regulation Of Protein Localization Positive Regulation Of Transport Spindle Pole Centrosome Trans-Golgi Network Membrane Golgi Apparatus Positive Regulation Of Protein Export From Nucleus Vesicle Organization Negative Regulation Of Canonical Wnt Signaling Pathway Vesicle-mediated Transport To The Plasma Membrane Golgi Membrane Amyloid Fibril Formation Phosphatidylinositol-4-phosphate Binding Positive Regulation Of Excitatory Postsynaptic Potential Regulation Of Transport Vesicle Budding From Membrane Negative Regulation Of Wnt Signaling Pathway Vesicle-mediated Transport Regulation Of Protein Export From Nucleus SNAP Receptor Activity Golgi To Plasma Membrane Protein Transport Amyloid-beta Complex Growth Cone Lamellipodium Neuron Projection Organization Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Regulation Of Long-term Synaptic Potentiation TMEM240-body Regulation Of Microtubule Anchoring At Centrosome SNARE Complex Myosin Head/neck Binding Calcitriol Binding Lithocholic Acid Binding Trans-Golgi Network Negative Regulation Of Protein Localization To Nucleus Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Modulation Of Excitatory Postsynaptic Potential Nuclear Inner Membrane Cellular Response To Amyloid-beta	TRC Complex Positive Regulation Of ERAD Pathway Regulation Of ERAD Pathway Positive Regulation Of Response To Endoplasmic Reticulum Stress Positive Regulation Of Proteolysis Regulation Of Monoatomic Cation Transmembrane Transport Regulation Of Monoatomic Ion Transmembrane Transport Regulation Of Response To Endoplasmic Reticulum Stress Post-translational Protein Targeting To Endoplasmic Reticulum Membrane ERAD Pathway Regulation Of Metal Ion Transport Positive Regulation Of Proteasomal Protein Catabolic Process Regulation Of Proteolysis Regulation Of Monoatomic Ion Transport Positive Regulation Of Proteolysis Involved In Protein Catabolic Process Regulation Of Cellular Response To Stress Protein Targeting To ER Establishment Of Protein Localization To Endoplasmic Reticulum Regulation Of Proteasomal Protein Catabolic Process Positive Regulation Of Protein Catabolic Process Calcium Ion Binding Polyubiquitin Modification-dependent Protein Binding Response To Endoplasmic Reticulum Stress Potassium Channel Regulator Activity Positive Regulation Of Protein Metabolic Process Intramembranous Bone Growth Negative Regulation Of Store-operated Calcium Channel Activity Regulation Of Potassium Ion Transmembrane Transport Protein Targeting To Membrane Regulation Of Transport Potassium Channel Activity Voltage-gated Potassium Channel Complex Regulation Of Transmembrane Transporter Activity Regulation Of Monoatomic Ion Transmembrane Transporter Activity Regulation Of Protein Catabolic Process Autophagosome Regulation Of Potassium Ion Transport Peptidyl-aspartic Acid 3-dioxygenase Activity Negative Regulation Of G Protein-coupled Receptor Internalization Kv4.3-KChIP1 Channel Complex Autophagosome Assembly Autophagosome Organization Regulation Of Inositol 1,4,5-trisphosphate-sensitive Calcium-release Channel Activity Proteasomal Protein Catabolic Process Negative Regulation Of Toll-like Receptor 3 Signaling Pathway Monoatomic Ion Channel Complex BAT3 Complex Binding Localization Within Membrane Negative Regulation Of Clathrin-dependent Endocytosis Transmembrane Transporter Binding
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