IGF2R

Gene Name		insulin-like growth factor 2 receptor
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Gene Ontology Annotations	Cellular Component	Extracellular Space Nuclear Envelope Lumen Lysosomal Membrane Endosome Late Endosome Trans-Golgi Network Integral Component Of Plasma Membrane Focal Adhesion Cell Surface Membrane Clathrin Coat Endocytic Vesicle Trans-Golgi Network Transport Vesicle Perinuclear Region Of Cytoplasm Extracellular Vesicular Exosome
	Molecular Function	Glycoprotein Binding G-protein Alpha-subunit Binding Retinoic Acid Binding Receptor Activity G-protein Coupled Receptor Activity Insulin-like Growth Factor-activated Receptor Activity Transporter Activity Protein Binding Mannose Binding Enzyme Binding Insulin-like Growth Factor II Binding Identical Protein Binding Phosphoprotein Binding
	Biological Process	Liver Development Receptor-mediated Endocytosis Signal Transduction G-protein Coupled Receptor Signaling Pathway Spermatogenesis Post-embryonic Development Organ Regeneration Response To Retinoic Acid Positive Regulation Of Apoptotic Process Insulin-like Growth Factor Receptor Signaling Pathway
Pathways		Golgi Associated Vesicle Biogenesis trans-Golgi Network Vesicle Budding Clathrin derived vesicle budding
Drugs
Diseases
GWAS		Brain lesion load ( 19010793)
Protein-protein Interactions		14 interactors: AGA ATXN1 CREG1 CSNK2A1 CTSD GGA1 GGA2 GGA3 GZMB IGF2 PACS1 PLAU PLAUR PLIN3
Entrez ID		3482
HPRD ID		00928
Ensembl ID		ENSG00000197081
Uniprot IDs		P11717
PDB IDs		1E6F 1GP0 1GP3 1GQB 1JPL 1JWG 1LF8 2CNJ 2L29 2L2A 2V5N 2V5O 2V5P
Enriched GO Terms of Interacting Partners?		Vesicle-mediated Transport Fibrinolysis Positive Regulation Of Protein Catabolic Process Negative Regulation Of Blood Coagulation Establishment Of Localization In Cell Negative Regulation Of Coagulation Urokinase Plasminogen Activator Signaling Pathway Negative Regulation Of Wound Healing Intracellular Transport Regulation Of Protein Catabolic Process Intracellular Protein Transport Cellular Localization Regulation Of Blood Coagulation Blood Coagulation Regulation Of Smooth Muscle Cell-matrix Adhesion Hemostasis Regulation Of Receptor Activity Protein Deglycosylation Insulin Receptor Signaling Pathway Via Phosphatidylinositol 3-kinase Regulation Of Mitotic Nuclear Division Regulation Of Wound Healing Positive Regulation Of Glycogen (starch) Synthase Activity Granzyme-mediated Apoptotic Signaling Pathway
Tagcloud ?		acting base box constitutes copies differentially discrimination distinguish dmr dmrs embryo encodes erased establishment germ gonads imprint imprinted imprinting includes maintained mark methylated methylation novo pair parent paternal phenomenon