THAP11 and SLX1B

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		THAP11	SLX1B
Gene Name		THAP domain containing 11	SLX1 structure-specific endonuclease subunit homolog B (S. cerevisiae)
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Cytoplasm Intercellular Bridge	Slx1-Slx4 Complex
	Molecular Function	DNA Binding Protein Binding Zinc Ion Binding	Protein Binding Crossover Junction Endodeoxyribonuclease Activity 5'-flap Endonuclease Activity Metal Ion Binding
	Biological Process	Transcription, DNA-templated Regulation Of Transcription, DNA-templated	Double-strand Break Repair Via Homologous Recombination DNA Catabolic Process, Endonucleolytic DNA Repair DNA Double-strand Break Processing Involved In Repair Via Single-strand Annealing
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		16 interactors: C9orf16 CASP3 CTBP1 ECT2 HCFC1 HDAC1 HDAC3 LRRC45 PFDN6 PSMC5 SIN3A SLX1B SRSF11 THAP7 TPX2 VPS52	3 interactors: DUSP10 THAP11 TUBA1B
Entrez ID		57215	79008
HPRD ID		11629	14673
Ensembl ID		ENSG00000168286	ENSG00000181625
Uniprot IDs		Q96EK4	Q9BQ83
PDB IDs		2LAU
Enriched GO Terms of Interacting Partners?		Regulation Of Cell Cycle Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Histone Modification Positive Regulation Of Cellular Metabolic Process Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Neurotrophin TRK Receptor Signaling Pathway Histone Deacetylation Transcription From RNA Polymerase II Promoter Neurotrophin Signaling Pathway Protein Deacetylation Negative Regulation Of Cellular Metabolic Process Positive Regulation Of Cell Cycle Chromatin Modification Transcription, DNA-templated RNA Biosynthetic Process Positive Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Metabolic Process Chromatin Organization Positive Regulation Of Protein Metabolic Process Nucleobase-containing Compound Metabolic Process Negative Regulation Of Histone Acetylation Negative Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Cellular Component Organization Regulation Of Cellular Protein Metabolic Process Negative Regulation Of Peptidyl-lysine Acetylation Regulation Of Mitotic Cell Cycle Cell Cycle Negative Regulation Of Protein Acetylation Histone H4 Deacetylation Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Negative Regulation Of Cell Cycle Regulation Of Apoptotic Process Positive Regulation Of Protein Modification Process Negative Regulation Of Apoptotic Process Cellular Nitrogen Compound Metabolic Process Regulation Of Protein Metabolic Process Negative Regulation Of Programmed Cell Death Regulation Of Cell Cycle Process Cellular Response To Stress Regulation Of Cell Death Histone H3 Deacetylation Cellular Response To Oxidative Stress Regulation Of Protein Localization To Nucleus Histone H3-K9 Modification Negative Regulation Of Cell Death RNA Metabolic Process	Negative Regulation Of Respiratory Burst Involved In Inflammatory Response Negative Regulation Of Protein Kinase Activity By Regulation Of Protein Phosphorylation Regulation Of Brown Fat Cell Differentiation Regulation Of Respiratory Burst Negative Regulation Of JUN Kinase Activity
Tagcloud ?		blastocysts bts cdh3 cdx2 chir99021 continually cyp11a1 dome elf5 eomes ets2 feeders gcm1 gdf3 hand1 hsd17b1 mash2 nanog oct4 pd0325901 pparg smarca4 sox2 ssea tdk tead4 teratomas tfap2a tscs
Tagcloud (Difference) ?		blastocysts bts cdh3 cdx2 chir99021 continually cyp11a1 dome elf5 eomes ets2 feeders gcm1 gdf3 hand1 hsd17b1 mash2 nanog oct4 pd0325901 pparg smarca4 sox2 ssea tdk tead4 teratomas tfap2a tscs
Tagcloud (Intersection) ?