THAP11 and VPS52

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		THAP11	VPS52
Gene Name		THAP domain containing 11	vacuolar protein sorting 52 homolog (S. cerevisiae)
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Cytoplasm Intercellular Bridge	Golgi Apparatus Endosome Membrane Perinuclear Region Of Cytoplasm
	Molecular Function	DNA Binding Protein Binding Zinc Ion Binding	Protein Binding Syntaxin Binding
	Biological Process	Transcription, DNA-templated Regulation Of Transcription, DNA-templated	Ectodermal Cell Differentiation Protein Transport Embryonic Ectodermal Digestive Tract Development
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		16 interactors: C9orf16 CASP3 CTBP1 ECT2 HCFC1 HDAC1 HDAC3 LRRC45 PFDN6 PSMC5 SIN3A SLX1B SRSF11 THAP7 TPX2 VPS52	49 interactors: AAMP ARNT2 ATP6V1D C1orf109 CACNA1A CCDC146 CCDC33 DDX6 EPM2AIP1 FAM184A GFM2 GOLGA1 HAUS1 HEATR1 KANK2 KIAA1217 KIF5B KLC3 LMO4 MAPK3 METTL13 MFAP1 MRPL11 NFKBIB NOP2 PPP1R18 PRKAA1 PRKAA2 RAB4A RNF41 SH2D4A STX11 TBC1D22B TCEANC TEAD4 THAP11 TPM3 TRAF6 TSSK3 TSTD2 TXLNA TXN2 USP2 VPS28 VPS51 VPS53 VPS54 WTAP ZMAT2
Entrez ID		57215	6293
HPRD ID		11629	09142
Ensembl ID		ENSG00000168286	ENSG00000223501
Uniprot IDs		Q96EK4	B4DNI9 Q8N1B4
PDB IDs		2LAU
Enriched GO Terms of Interacting Partners?		Regulation Of Cell Cycle Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Histone Modification Positive Regulation Of Cellular Metabolic Process Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Neurotrophin TRK Receptor Signaling Pathway Histone Deacetylation Transcription From RNA Polymerase II Promoter Neurotrophin Signaling Pathway Protein Deacetylation Negative Regulation Of Cellular Metabolic Process Positive Regulation Of Cell Cycle Chromatin Modification Transcription, DNA-templated RNA Biosynthetic Process Positive Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Metabolic Process Chromatin Organization Positive Regulation Of Protein Metabolic Process Nucleobase-containing Compound Metabolic Process Negative Regulation Of Histone Acetylation Negative Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Cellular Component Organization Regulation Of Cellular Protein Metabolic Process Negative Regulation Of Peptidyl-lysine Acetylation Regulation Of Mitotic Cell Cycle Cell Cycle Negative Regulation Of Protein Acetylation Histone H4 Deacetylation Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Negative Regulation Of Cell Cycle Regulation Of Apoptotic Process Positive Regulation Of Protein Modification Process Negative Regulation Of Apoptotic Process Cellular Nitrogen Compound Metabolic Process Regulation Of Protein Metabolic Process Negative Regulation Of Programmed Cell Death Regulation Of Cell Cycle Process Cellular Response To Stress Regulation Of Cell Death Histone H3 Deacetylation Cellular Response To Oxidative Stress Regulation Of Protein Localization To Nucleus Histone H3-K9 Modification Negative Regulation Of Cell Death RNA Metabolic Process	Anion Homeostasis Toll-like Receptor 5 Signaling Pathway Toll-like Receptor 10 Signaling Pathway Establishment Of Localization In Cell Insulin Receptor Signaling Pathway Toll-like Receptor TLR6:TLR2 Signaling Pathway Toll-like Receptor TLR1:TLR2 Signaling Pathway Response To Insulin Toll-like Receptor 2 Signaling Pathway Toll-like Receptor 9 Signaling Pathway Regulation Of Energy Homeostasis TRIF-dependent Toll-like Receptor Signaling Pathway Autophagy Cellular Localization Retrograde Transport, Endosome To Golgi Positive Regulation Of Glycolytic Process MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway Intracellular Transport MyD88-dependent Toll-like Receptor Signaling Pathway Fatty Acid Homeostasis Regulation Of Generation Of Precursor Metabolites And Energy Toll-like Receptor 4 Signaling Pathway Interleukin-1-mediated Signaling Pathway Endosomal Transport Cellular Response To Insulin Stimulus Gene Expression Regulation Of Circadian Rhythm Histone-serine Phosphorylation Cellular Response To Glucose Starvation Toll-like Receptor Signaling Pathway RNA Metabolic Process Regulation Of Glycolytic Process Response To Peptide Hormone Response To Hormone Negative Regulation Of TOR Signaling Response To Peptide Cholesterol Biosynthetic Process Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Cerebellar Molecular Layer Development Negative Regulation Of Apolipoprotein Binding Negative Regulation Of Glucosylceramide Biosynthetic Process Cold Acclimation Positive Regulation Of Autophagy Activation Of MAPK Activity Activation Of Innate Immune Response Organelle Disassembly Cellular Response To Peptide Hormone Stimulus Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Tagcloud ?		blastocysts bts cdh3 cdx2 chir99021 continually cyp11a1 dome elf5 eomes ets2 feeders gcm1 gdf3 hand1 hsd17b1 mash2 nanog oct4 pd0325901 pparg smarca4 sox2 ssea tdk tead4 teratomas tfap2a tscs	biosynthetic buildup cargo cathepsin correspond cycling endosomes explaining garp hydrolase hydrolases impairs intermediates lysosomes missorting mprs recycling relies retrograde shiga sorting swollen tgn tgn46 undegraded vesicles vps53 vps54 wobbler
Tagcloud (Difference) ?		blastocysts bts cdh3 cdx2 chir99021 continually cyp11a1 dome elf5 eomes ets2 feeders gcm1 gdf3 hand1 hsd17b1 mash2 nanog oct4 pd0325901 pparg smarca4 sox2 ssea tdk tead4 teratomas tfap2a tscs	biosynthetic buildup cargo cathepsin correspond cycling endosomes explaining garp hydrolase hydrolases impairs intermediates lysosomes missorting mprs recycling relies retrograde shiga sorting swollen tgn tgn46 undegraded vesicles vps53 vps54 wobbler
Tagcloud (Intersection) ?