PRMT3 and PABPN1

Number of citations of the paper that reports this interaction (PMID 10224081)
44

Data Source:
HPRD (in vitro)

		PRMT3	PABPN1
Gene Name		protein arginine methyltransferase 3	poly(A) binding protein, nuclear 1
Image
Gene Ontology Annotations	Cellular Component	Cytoplasm Cytosol Ribosome	Nucleus Nucleoplasm Cytoplasm Ribonucleoprotein Complex
	Molecular Function	Protein Binding Methyltransferase Activity Histone-arginine N-methyltransferase Activity Protein-arginine N-methyltransferase Activity Protein-arginine Omega-N Asymmetric Methyltransferase Activity Metal Ion Binding Modified Amino Acid Binding	Nucleotide Binding RNA Binding Protein Binding Poly(A) RNA Binding
	Biological Process	Regulation Of Transcription, DNA-templated Peptidyl-arginine Methylation, To Asymmetrical-dimethyl Arginine Negative Regulation Of Protein Ubiquitination Histone Arginine Methylation	MRNA Splicing, Via Spliceosome Transcription From RNA Polymerase II Promoter Termination Of RNA Polymerase II Transcription RNA Processing Muscle Contraction RNA Splicing Gene Expression Poly(A)+ MRNA Export From Nucleus Modulation By Virus Of Host Morphology Or Physiology Modulation By Virus Of Host Process Viral Life Cycle MRNA 3'-end Processing Modification By Virus Of Host MRNA Processing
Pathways			mRNA Splicing Inhibition of Host mRNA Processing and RNA Silencing Processing of Capped Intron-Containing Pre-mRNA RNA Polymerase II Transcription mRNA Splicing - Major Pathway Cleavage of Growing Transcript in the Termination Region Host Interactions with Influenza Factors mRNA 3'-end processing Processing of Intronless Pre-mRNAs Influenza Infection NS1 Mediated Effects on Host Pathways Processing of Capped Intronless Pre-mRNA RNA Polymerase II Transcription Termination
Drugs
Diseases
GWAS
Protein-Protein Interactions		7 interactors: FBL HNRNPA1 PABPN1 PPARD RASSF2 RPS2 STAT1	11 interactors: CARM1 DNAJB4 HNRNPA1 IL7R LATS1 PRMT3 SMARCA4 SNW1 STAU1 TNPO1 YWHAQ
Entrez ID		10196	8106
HPRD ID		11934	03787
Ensembl ID		ENSG00000185238
Uniprot IDs		O60678 Q8WUV3	Q86U42
PDB IDs		2FYT 3SMQ 4HSG	3B4D 3B4M 3UCG
Enriched GO Terms of Interacting Partners?		Viral Process RNA Metabolic Process RNA Export From Nucleus Negative Regulation Of Macrophage Fusion Epidermal Growth Factor Receptor Signaling Pathway Via I-kappaB Kinase/NF-kappaB Cascade Histone Glutamine Methylation Nucleobase-containing Compound Metabolic Process Regulation Of Smooth Muscle Cell Proliferation MRNA Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Nuclear Export MRNA Transport Negative Regulation By Virus Of Viral Protein Levels In Host Cell Modification By Virus Of Host MRNA Processing Negative Regulation Of Metanephric Nephron Tubule Epithelial Cell Differentiation Peptidyl-glutamine Methylation Negative Regulation Of Epithelial Cell Proliferation RNA Transport Cytoplasmic Transport RNA Localization Negative Regulation Of Nephron Tubule Epithelial Cell Differentiation Metanephric Mesenchymal Cell Proliferation Involved In Metanephros Development Nitrogen Compound Metabolic Process Gene Expression Negative Regulation Of NIK/NF-kappaB Signaling SnoRNA Metabolic Process Viral Life Cycle Metanephric Mesenchymal Cell Differentiation Transcription From RNA Polymerase II Promoter Response To Nutrient Keratinocyte Migration Negative Regulation Of Syncytium Formation By Plasma Membrane Fusion Negative Regulation Of Mesenchymal To Epithelial Transition Involved In Metanephros Morphogenesis MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Negative Regulation Of Collagen Biosynthetic Process Vitamin A Metabolic Process Nucleocytoplasmic Transport Nuclear Transport Mesenchymal Cell Differentiation Involved In Kidney Development Negative Regulation Of Multicellular Organismal Metabolic Process RNA Biosynthetic Process Ossification Regulation Of Epithelial Cell Proliferation Cell Proliferation Involved In Metanephros Development Regulation Of Mesenchymal To Epithelial Transition Involved In Metanephros Morphogenesis Regulation Of Metanephric Nephron Tubule Epithelial Cell Differentiation Poly(A)+ MRNA Export From Nucleus	Positive Regulation Of Viral Process Positive Regulation By Host Of Viral Transcription Peptidyl-arginine Methylation, To Asymmetrical-dimethyl Arginine Peptidyl-arginine N-methylation Regulation Of Viral Process Histone Arginine Methylation Peptidyl-arginine Methylation Viral Process Interaction With Symbiont Positive Regulation Of Viral Transcription Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway Regulation Of Viral Transcription Histone H3-R17 Methylation Histone Modification Methylation Keratinocyte Differentiation Chromosome Organization Positive Regulation Of Vitamin D Receptor Signaling Pathway Interleukin-7-mediated Signaling Pathway Histone H3-R2 Methylation Negative Regulation Of Transcription From RNA Polymerase II Promoter During Mitosis Positive Regulation By Virus Of Viral Protein Levels In Host Cell Histone Methylation Nuclear Import Negative Regulation Of Cellular Metabolic Process Regulation Of Growth Plate Cartilage Chondrocyte Proliferation DNA Methylation On Cytosine Within A CG Sequence Epidermal Cell Differentiation RNA Localization Negative Regulation Of T Cell Mediated Cytotoxicity Chromatin Modification Regulation Of Nitrogen Compound Metabolic Process Regulation Of Vitamin D Receptor Signaling Pathway Definitive Erythrocyte Differentiation Aortic Smooth Muscle Cell Differentiation Protein Methylation Cellular Localization Intrinsic Apoptotic Signaling Pathway Glial Cell Fate Determination Methylation-dependent Chromatin Silencing Response To Organic Substance Chromatin Organization Intracellular Receptor Signaling Pathway Regulation Of Cell Differentiation Skin Development MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Intracellular MRNA Localization Regulation Of Signal Transduction Homeostasis Of Number Of Cells
Tagcloud ?		bbrd brucei clade clades connects dart dihydrolipoamide exemplified fmr homologues methyltransferases outgroup paralogue phylogeny prmt1 prmt2 prmt4 prmt5 prmt6 prmt7 prmt8 prmt9 prmts reconstructing resolve tbprmts tedious trypanosoma uncharacterized	advances appreciated atypical avoid avoidance awareness biopsy cardinal chinese confusion decade dysphagia dystrophy earlier hoped investigations judicious last muscle muscular oculopharyngeal professionals proximal ptosis reserved rule underdiagnosed unnecessary weakness
Tagcloud (Difference) ?		bbrd brucei clade clades connects dart dihydrolipoamide exemplified fmr homologues methyltransferases outgroup paralogue phylogeny prmt1 prmt2 prmt4 prmt5 prmt6 prmt7 prmt8 prmt9 prmts reconstructing resolve tbprmts tedious trypanosoma uncharacterized	advances appreciated atypical avoid avoidance awareness biopsy cardinal chinese confusion decade dysphagia dystrophy earlier hoped investigations judicious last muscle muscular oculopharyngeal professionals proximal ptosis reserved rule underdiagnosed unnecessary weakness
Tagcloud (Intersection) ?