PRMT3

Description		protein arginine methyltransferase 3
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GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol
	Molecular Function	Protein Binding Methyltransferase Activity Zinc Ion Binding Protein-arginine N-methyltransferase Activity Transferase Activity Protein-arginine Omega-N Monomethyltransferase Activity Protein-arginine Omega-N Asymmetric Methyltransferase Activity Histone Methyltransferase Activity Histone H4R3 Methyltransferase Activity Metal Ion Binding
	Biological Process	Chromatin Remodeling Regulation Of DNA-templated Transcription Negative Regulation Of Protein Ubiquitination Methylation Positive Regulation Of Osteoblast Differentiation Transcription Initiation-coupled Chromatin Remodeling Negative Regulation Of Retinoic Acid Biosynthetic Process
Pathways		RMTs methylate histone arginines Protein methylation
Drugs		S-adenosyl-L-homocysteine
Diseases
GWAS		Carotid intima media thickness (maximum) ( 31801372) Number of alcoholic drinks required to feel an effect (long-term average) ( 31270906) Pursuit maintenance gain ( 29064472) Response to inhaled glucocorticoid treatment in asthma (change in FEV1) ( 25601762)
Interacting Genes		11 interacting genes: BEND7 FBL HNRNPA1 MEOX2 PABPN1 PIH1D2 PPARD RASSF2 STAT1 TMEM132D TSC22D2
Entrez ID		10196
HPRD ID		11934
Ensembl ID		ENSG00000185238
Uniprot IDs		O60678 Q8WUV3
PDB IDs		2FYT 3SMQ 4HSG 4QQN 4RYL 8G2F 8G2G 8SHB 8SHR 8SIO
Enriched GO Terms of Interacting Partners?		Ribonucleoprotein Complex
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