DUX4L9 and SF1

Number of citations of the paper that reports this interaction (PubMedID 26816005)
133

Data Source:
BioGRID (two hybrid)

		DUX4L9	SF1
Description		double homeobox 4 like 9 (pseudogene)	splicing factor 1
Image		No pdb structure
GO Annotations	Cellular Component		Nucleus Nucleoplasm Spliceosomal Complex Ribosome U2AF Complex
	Molecular Function		Nucleic Acid Binding Transcription Corepressor Activity RNA Binding MRNA Binding Protein Binding Zinc Ion Binding Identical Protein Binding Metal Ion Binding
	Biological Process		Spliceosomal Complex Assembly MRNA 3'-splice Site Recognition MRNA Splicing, Via Spliceosome MRNA Processing RNA Splicing MRNA Cis Splicing, Via Spliceosome Negative Regulation Of DNA-templated Transcription Negative Regulation Of Smooth Muscle Cell Proliferation Regulation Of Primary Metabolic Process
Pathways			mRNA Splicing - Major Pathway
Drugs			Artenimol
Diseases
GWAS			Mean reticulocyte volume ( 32888494) Urate levels ( 21768215)
Interacting Genes		10 interacting genes: ACTA1 ACTN3 FHL3 MSS51 MYH2 NDUFB10 RBM24 RPL4 SF1 VDAC2	90 interacting genes: ALG13 APBB1 APOBEC3C ATXN1 BAG4 BCAS2 BCL2 BUD31 CDC42 CEBPA CEP55 CPSF7 CTBP1 CTTN DCN DDX17 DMRTB1 DUX4L9 EWSR1 EXOSC1 EXOSC8 FAM168A FUS GAS7 HNRNPF HNRNPH1 HNRNPH2 HNRNPK HNRNPUL1 IDH3A IL7R ILF3 ITCH KHDRBS2 KPNA1 KRT31 KRTAP26-1 LINC00632 MIR106B MIR155 MIR19B2 MIR34A MIRLET7G MKRN3 NCK2 NEIL3 NFKB1 OGT OSTF1 PDAP1 PLSCR1 PRKG1 PRPF39 PRPF40A PRRC2B PSMA3 PUF60 PUS7 RBFOX2 RBM10 RBM17 RBM4 RBM7 RBMX RBPMS RPA2 RSPH1 SEC23A SF3B1 SF3B4 SFPQ SNRPA TAF15 TCERG1 TFIP11 TNPO2 TRIM23 TRIM69 TTN TXNL4B U2AF2 UBL5 USO1 WBP4 WDR77 WDR83 WWP2 YTHDF1 YTHDF3 ZNF461
Entrez ID		100288711	7536
HPRD ID			03306
Ensembl ID		ENSG00000224807	ENSG00000168066
Uniprot IDs			A0A7P0T9U7 A0A9L9PXE4 B4DX42 H7C561 Q15637
PDB IDs			1K1G 1O0P 1OPI 2M09 2M0G 4FXW 4FXX 7VH9 7VPX 8PXX
Enriched GO Terms of Interacting Partners?		Sarcomere Actin Filament Muscle System Process Stress Fiber Regulation Of Myotube Differentiation Actin Binding Regulation Of Striated Muscle Cell Differentiation Positive Regulation Of Glucose Catabolic Process To Lactate Via Pyruvate Regulation Of The Force Of Skeletal Muscle Contraction Positive Regulation Of Striated Muscle Cell Differentiation Positive Regulation Of Fast-twitch Skeletal Muscle Fiber Contraction Positive Regulation Of Muscle Cell Differentiation Muscle Cell Development Actin Filament-based Process Positive Regulation Of Bone Mineralization Involved In Bone Maturation Focal Adhesion Positive Regulation Of Skeletal Muscle Fiber Differentiation Skeletal Muscle Thin Filament Assembly Mesenchyme Migration Negative Regulation Of Relaxation Of Muscle Regulation Of Muscle Cell Differentiation Response To Denervation Involved In Regulation Of Muscle Adaptation Positive Regulation Of Skeletal Muscle Tissue Growth Transition Between Fast And Slow Fiber Regulation Of Skeletal Muscle Tissue Growth Skeletal Muscle Atrophy Skeletal Muscle Adaptation Striated Muscle Atrophy Z Disc Porin Activity Voltage-gated Monoatomic Anion Channel Activity U2AF Complex MRNA 3'-splice Site Recognition Positive Regulation Of 3'-UTR-mediated MRNA Stabilization MRNA CDS Binding Regulation Of Skeletal Muscle Fiber Differentiation Striated Muscle Thin Filament Muscle Atrophy Response To Muscle Inactivity Positive Regulation Of Skeletal Muscle Fiber Development Negative Regulation Of Cellular Respiration Negative Regulation Of Oxidative Phosphorylation Ribosome Ceramide Binding Mitochondrial Outer Membrane Permeabilization Negative Regulation Of Cytoplasmic Translation Positive Regulation Of Skeletal Muscle Cell Differentiation Muscle Contraction Regulation Of Skeletal Muscle Fiber Development Actin Filament Binding	RNA Splicing MRNA Processing MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions RNA Processing MRNA Metabolic Process RNA Binding RNA Metabolic Process Nucleic Acid Binding Regulation Of RNA Splicing Nucleic Acid Metabolic Process Spliceosomal Complex Regulation Of MRNA Metabolic Process Regulation Of MRNA Splicing, Via Spliceosome Regulation Of MRNA Processing Nucleobase-containing Compound Metabolic Process Nucleoplasm Nucleus Macromolecule Metabolic Process Regulation Of Alternative MRNA Splicing, Via Spliceosome Alternative MRNA Splicing, Via Spliceosome Regulation Of Metabolic Process Regulation Of Macromolecule Metabolic Process Catalytic Step 2 Spliceosome Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Metabolic Process Negative Regulation Of Gene Expression MRNA Binding Regulation Of Primary Metabolic Process Negative Regulation Of Macromolecule Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of Biosynthetic Process Nuclear Speck Negative Regulation Of Macromolecule Biosynthetic Process Post-transcriptional Regulation Of Gene Expression Negative Regulation Of MRNA Metabolic Process U2-type Prespliceosome Identical Protein Binding Regulatory NcRNA-mediated Gene Silencing Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Macromolecule Metabolic Process Regulation Of RNA Metabolic Process Positive Regulation Of RNA Metabolic Process Ribonucleoprotein Complex Negative Regulation Of MRNA Splicing, Via Spliceosome MRNA 3'-UTR Binding Positive Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Biosynthetic Process Negative Regulation Of RNA Splicing
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?