DUX4L9 and VDAC2

Number of citations of the paper that reports this interaction (PubMedID 26816005)
133

Data Source:
BioGRID (two hybrid)

		DUX4L9	VDAC2
Description		double homeobox 4 like 9 (pseudogene)	voltage dependent anion channel 2
Image		No pdb structure
GO Annotations	Cellular Component		Acrosomal Vesicle Nucleus Mitochondrion Mitochondrial Outer Membrane Membrane Mitochondrial Membrane Mitochondrial Nucleoid Membrane Raft Pore Complex Sperm Midpiece
	Molecular Function		Nucleotide Binding Voltage-gated Monoatomic Ion Channel Activity Protein Binding ATP Binding Oxysterol Binding Lipid Binding Voltage-gated Monoatomic Anion Channel Activity Porin Activity Cholesterol Binding Phospholipid Scramblase Activity Phosphatidylcholine Binding Ceramide Binding
	Biological Process		Monoatomic Ion Transport Monoatomic Anion Transport Lipid Transport Binding Of Sperm To Zona Pellucida Plasma Membrane Phospholipid Scrambling Phospholipid Translocation Transmembrane Transport Mitochondrial Outer Membrane Permeabilization Monoatomic Anion Transmembrane Transport Mitochondrial Transmembrane Transport
Pathways			PINK1-PRKN Mediated Mitophagy Ub-specific processing proteases Mitochondrial calcium ion transport
Drugs			Aluminium monostearate PRLX 93936
Diseases
GWAS
Interacting Genes		10 interacting genes: ACTA1 ACTN3 FHL3 MSS51 MYH2 NDUFB10 RBM24 RPL4 SF1 VDAC2	12 interacting genes: ADRB2 APP BAK1 CFTR CYCS DUX4 DUX4L9 ECT2 HK1 NEDD4 NEDD4L RPS3A
Entrez ID		100288711	7417
HPRD ID			01904
Ensembl ID		ENSG00000224807	ENSG00000165637
Uniprot IDs			A0A024QZT0 B4DKM5 P45880
PDB IDs			9EIH 9EII 9EIJ
Enriched GO Terms of Interacting Partners?		Sarcomere Actin Filament Muscle System Process Stress Fiber Regulation Of Myotube Differentiation Actin Binding Regulation Of Striated Muscle Cell Differentiation Positive Regulation Of Glucose Catabolic Process To Lactate Via Pyruvate Regulation Of The Force Of Skeletal Muscle Contraction Positive Regulation Of Striated Muscle Cell Differentiation Positive Regulation Of Fast-twitch Skeletal Muscle Fiber Contraction Positive Regulation Of Muscle Cell Differentiation Muscle Cell Development Actin Filament-based Process Positive Regulation Of Bone Mineralization Involved In Bone Maturation Focal Adhesion Positive Regulation Of Skeletal Muscle Fiber Differentiation Skeletal Muscle Thin Filament Assembly Mesenchyme Migration Negative Regulation Of Relaxation Of Muscle Regulation Of Muscle Cell Differentiation Response To Denervation Involved In Regulation Of Muscle Adaptation Positive Regulation Of Skeletal Muscle Tissue Growth Transition Between Fast And Slow Fiber Regulation Of Skeletal Muscle Tissue Growth Skeletal Muscle Atrophy Skeletal Muscle Adaptation Striated Muscle Atrophy Z Disc Porin Activity Voltage-gated Monoatomic Anion Channel Activity U2AF Complex MRNA 3'-splice Site Recognition Positive Regulation Of 3'-UTR-mediated MRNA Stabilization MRNA CDS Binding Regulation Of Skeletal Muscle Fiber Differentiation Striated Muscle Thin Filament Muscle Atrophy Response To Muscle Inactivity Positive Regulation Of Skeletal Muscle Fiber Development Negative Regulation Of Cellular Respiration Negative Regulation Of Oxidative Phosphorylation Ribosome Ceramide Binding Mitochondrial Outer Membrane Permeabilization Negative Regulation Of Cytoplasmic Translation Positive Regulation Of Skeletal Muscle Cell Differentiation Muscle Contraction Regulation Of Skeletal Muscle Fiber Development Actin Filament Binding	Regulation Of Membrane Potential Regulation Of Monoatomic Ion Transport Regulation Of Monoatomic Ion Transmembrane Transport Regulation Of Metal Ion Transport Negative Regulation Of Potassium Ion Export Across Plasma Membrane Positive Regulation Of Transport Regulation Of Sodium Ion Transport Sodium Channel Inhibitor Activity Potassium Channel Inhibitor Activity Regulation Of Monoatomic Cation Transmembrane Transport Regulation Of Transport Regulation Of Potassium Ion Export Across Plasma Membrane Negative Regulation Of Sodium Ion Transport Protein-folding Chaperone Binding Positive Regulation Of CAMP/PKA Signal Transduction Receptor Catabolic Process Neuronal Dense Core Vesicle Transmembrane Transporter Binding Negative Regulation Of Potassium Ion Transmembrane Transport Enzyme Binding Positive Regulation Of Protein Metabolic Process Positive Regulation Of Excitatory Postsynaptic Potential Endocytosis Ionotropic Glutamate Receptor Signaling Pathway Receptor-mediated Endocytosis Cell Junction Organization Response To Radiation Cellular Response To Radiation Negative Regulation Of Potassium Ion Transport Positive Regulation Of Macromolecule Metabolic Process Neuromuscular Junction Development Cytosol Ligand-gated Ion Channel Signaling Pathway Positive Regulation Of Protein Catabolic Process Positive Regulation Of Response To Endoplasmic Reticulum Stress Intracellular Chemical Homeostasis Regulation Of Cellular Localization Positive Regulation Of Metabolic Process Regulation Of CAMP/PKA Signal Transduction Import Into Cell Positive Regulation Of Cell Communication Glutamate Receptor Signaling Pathway Positive Regulation Of Intracellular Signal Transduction Regulation Of Systemic Arterial Blood Pressure By Norepinephrine-epinephrine Cellular Response To Amyloid-beta Modulation Of Excitatory Postsynaptic Potential Positive Regulation Of Catabolic Process Positive Regulation Of Signaling Positive Regulation Of Biomineral Tissue Development Positive Regulation Of Mini Excitatory Postsynaptic Potential
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