RIT1

Description		Ras like without CAAX 1
Image
GO Annotations	Cellular Component	Plasma Membrane Membrane
	Molecular Function	Nucleotide Binding GTPase Activity G Protein Activity Protein Binding Calmodulin Binding GTP Binding Hydrolase Activity GDP Binding
	Biological Process	Signal Transduction Ras Protein Signal Transduction
Pathways		Signalling to p38 via RIT and RIN
Drugs
Diseases
GWAS		Birth weight ( 31043758) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Body mass index ( 28892062) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Conduct disorder (maternal expressed emotions interaction) ( 18846501) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (min-P) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Crohn's disease ( 28067908) Immature fraction of reticulocytes ( 32888494) Inflammatory bowel disease ( 23128233 28067908) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) White matter hyperintensity volume ( 33293549) White matter hyperintensity volume (adjusted for hypertension) ( 33293549) White matter hyperintensity volume x hypertension interaction (2df) ( 33293549)
Interacting Genes		16 interacting genes: AFDN AP2A1 CUL3 IFRD1 KLHL12 LRIF1 LRRK2 PTN RALGDS RGL1 RGL3 RLF SMAD2 SMAD3 SMURF1 SRPK2
Entrez ID		6016
HPRD ID		10195
Ensembl ID		ENSG00000143622
Uniprot IDs		Q92963
PDB IDs		4KLZ
Enriched GO Terms of Interacting Partners?		I-SMAD Binding Transforming Growth Factor Beta Receptor Binding Signal Transduction Wnt Signaling Pathway Paraxial Mesoderm Morphogenesis R-SMAD Binding Intracellular Signaling Cassette Mesoderm Morphogenesis Gastrulation Pericardium Development SMAD Protein Complex Trophoblast Cell Migration Heteromeric SMAD Protein Complex Tissue Development Regulation Of Neuron Projection Development Embryonic Foregut Morphogenesis Nodal Signaling Pathway Co-SMAD Binding Ras Protein Signal Transduction Positive Regulation Of Gene Expression Primary MiRNA Processing Intracellular Signal Transduction Small GTPase-mediated Signal Transduction Neuron Projection Arborization Cell Surface Receptor Signaling Pathway Regulation Of Ossification COPII Vesicle Coating Regulation Of Plasma Membrane Bounded Cell Projection Organization Cellular Localization SMAD Protein Signal Transduction Regulation Of Cell Projection Organization Positive Regulation Of Cellular Component Organization Developmental Growth Embryonic Cranial Skeleton Morphogenesis Activin Receptor Signaling Pathway Cellular Developmental Process Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Cytosol Endoderm Development MiRNA Processing Vesicle Coating Cell Differentiation Transforming Growth Factor Beta Receptor Superfamily Signaling Pathway Ureteric Bud Development Negative Regulation Of Ossification Cell Surface Receptor Protein Serine/threonine Kinase Signaling Pathway Positive Regulation Of Bone Mineralization Regulation Of Cellular Component Organization Mesonephric Epithelium Development
Tagcloud ?