HTR6

Gene Name		5-hydroxytryptamine (serotonin) receptor 6, G protein-coupled
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Cilium Dendrite
	Molecular Function	Histamine Receptor Activity Serotonin Receptor Activity Protein Binding
	Biological Process	G-protein Coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Serotonin Receptor Signaling Pathway Synaptic Transmission Learning Negative Regulation Of Glutamate Secretion Negative Regulation Of Gamma-aminobutyric Acid Secretion Positive Regulation Of Gamma-aminobutyric Acid Secretion Negative Regulation Of Acetylcholine Secretion, Neurotransmission Cerebral Cortex Cell Migration Positive Regulation Of TOR Signaling Response To Estradiol Positive Regulation Of Dopamine Secretion Response To Drug Long-term Synaptic Potentiation
Pathways		Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD) Signaling by GPCR GPCR downstream signaling G alpha (s) signalling events Class A/1 (Rhodopsin-like receptors) Amine ligand-binding receptors Metabolic disorders of biological oxidation enzymes GPCR ligand binding Serotonin receptors
Drugs		Ziprasidone Olanzapine Clozapine Quetiapine Aripiprazole Dimethyltryptamine Iloperidone Sertindole Asenapine
Diseases
GWAS
Protein-protein Interactions		4 interactors: COPS5 FYN GNAQ GNAS
Entrez ID		3362
HPRD ID		03066
Ensembl ID		ENSG00000158748
Uniprot IDs		P50406
PDB IDs
Enriched GO Terms of Interacting Partners?		Platelet Activation Dopamine Receptor Signaling Pathway Blood Coagulation Hemostasis Adenylate Cyclase-activating G-protein Coupled Receptor Signaling Pathway Regulation Of Body Fluid Levels Wound Healing Cell Activation Response To Wounding Regulation Of Protein Localization Adenylate Cyclase-modulating G-protein Coupled Receptor Signaling Pathway Post-embryonic Body Morphogenesis Post-embryonic Development G-protein Coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Embryonic Limb Morphogenesis Regulation Of Cellular Localization Limb Morphogenesis Regulation Of Protein Localization To Nucleus Limb Development Exosomal Secretion Adenylate Cyclase-activating Adrenergic Receptor Signaling Pathway Cognition Regulation Of Phosphorus Metabolic Process Cellular Response To Peptide Hormone Stimulus Cellular Response To Peptide Homotypic Cell-cell Adhesion Regulation Of Cell Differentiation Phospholipase C-activating Dopamine Receptor Signaling Pathway Cullin Deneddylation Neuron Remodeling Detection Of Mechanical Stimulus Involved In Sensory Perception Of Pain Regulation Of Intracellular Signal Transduction Cellular Response To Platelet-derived Growth Factor Stimulus Protein Deneddylation Regulation Of Gene Expression Response To Platelet-derived Growth Factor Forebrain Development Response To Peptide Hormone Regulation Of Melanocyte Differentiation Adenylate Cyclase-activating Dopamine Receptor Signaling Pathway Cellular Response To Organonitrogen Compound Cellular Response To Prostaglandin E Stimulus Response To Parathyroid Hormone Positive Regulation Of CAMP-mediated Signaling Response To Peptide Response To Drug Maternal Behavior Adrenergic Receptor Signaling Pathway Secretion By Cell Single Organismal Cell-cell Adhesion
Tagcloud ?		alkenes azotic constructions gnai1 gnao1 heterocycle hm hms htr1b htr2a htr2b htr4 htr7 kpnb1 pharmacopeia prkaca prkca prkcb prkcd prkce prkcg prkd1 propertied pubchem rock2 rps6ka1 rps6ka3 tlr8 tradition