RPGRIP1 and TBC1D7

Data Source:
BioGRID (two hybrid)

		RPGRIP1	TBC1D7
Description		RPGR interacting protein 1	TBC1 domain family member 7
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GO Annotations	Cellular Component	Axoneme Photoreceptor Connecting Cilium Ciliary Transition Zone Photoreceptor Distal Connecting Cilium	Cytosol Cytoplasmic Vesicle Ciliary Basal Body
	Molecular Function	Protein Binding	GTPase Activator Activity Protein Binding Small GTPase Binding
	Biological Process	Visual Perception Retinal Rod Cell Development Response To Stimulus Neural Precursor Cell Proliferation Non-motile Cilium Assembly	Positive Regulation Of Protein Ubiquitination Negative Regulation Of TOR Signaling Positive Regulation Of GTPase Activity Response To Growth Factor Activation Of GTPase Activity Negative Regulation Of Cilium Assembly
Pathways			TBC/RABGAPs
Drugs
Diseases		Leber congenital amaurosis (LCR) Cone-rod dystrophy and cone dystrophy, including: Cone-rod dystrophy (CORD); Cone dystrophy (COD); Retinal cone dystrophy (RCD)
GWAS		Body mass index ( 26426971) Body mass index (age>50) ( 26426971) Body mass index x sex x age interaction (4df test) ( 26426971) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Height ( 31562340) Refractive error ( 32231278) Superior temporal sulcus banks volume ( 31530798)	Migraine ( 23793025) Migraine without aura ( 23793025)
Interacting Genes		26 interacting genes: AEN BRCA1 CBX8 CCDC146 CHCHD3 CSPP1 DPPA4 FAM74A4 FEM1C GATAD2B HEYL IQCE MAGEB2 NPHP4 PTF1A RNF6 RPGR RPP25L SCNM1 TBC1D7 TFPT TRIB3 ZNF337 ZNF417 ZNF564 ZNF688	30 interacting genes: AKT1 ALOX5 APP BAG4 BLZF1 GABARAPL1 HOOK1 IKBKG INCA1 KEAP1 KRT19 KRT35 LDOC1 LNX2 LZTS1 LZTS2 MAP1LC3A MIPOL1 MMADHC NEDD4 NEDD4L PICK1 RPGRIP1 SH3GLB2 SSNA1 TRAF4 TRIM62 TSC1 XPA YWHAZ
Entrez ID		57096	51256
HPRD ID		05673	18165
Ensembl ID		ENSG00000092200	ENSG00000145979
Uniprot IDs		Q96KN7	A0A024QZX0 A0A024R011 Q5JPB9 Q9P0N9 U3KPY5
PDB IDs		4QAM	3QWL 4Z6Y 5EJC 5ULO
Enriched GO Terms of Interacting Partners?
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