RPGRIP1 and FAM74A4

Data Source:
BioGRID (two hybrid)

		RPGRIP1	FAM74A4
Description		RPGR interacting protein 1	family with sequence similarity 74 member A4
Image			No pdb structure
GO Annotations	Cellular Component	Axoneme Photoreceptor Connecting Cilium Ciliary Transition Zone Photoreceptor Distal Connecting Cilium
	Molecular Function	Protein Binding	Protein Binding
	Biological Process	Visual Perception Retinal Rod Cell Development Response To Stimulus Neural Precursor Cell Proliferation Non-motile Cilium Assembly
Pathways
Drugs
Diseases		Leber congenital amaurosis (LCR) Cone-rod dystrophy and cone dystrophy, including: Cone-rod dystrophy (CORD); Cone dystrophy (COD); Retinal cone dystrophy (RCD)
GWAS		Body mass index ( 26426971) Body mass index (age>50) ( 26426971) Body mass index x sex x age interaction (4df test) ( 26426971) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Height ( 31562340) Refractive error ( 32231278) Superior temporal sulcus banks volume ( 31530798)
Interacting Genes		26 interacting genes: AEN BRCA1 CBX8 CCDC146 CHCHD3 CSPP1 DPPA4 FAM74A4 FEM1C GATAD2B HEYL IQCE MAGEB2 NPHP4 PTF1A RNF6 RPGR RPP25L SCNM1 TBC1D7 TFPT TRIB3 ZNF337 ZNF417 ZNF564 ZNF688	26 interacting genes: CCDC85B CCNDBP1 CEP44 EFEMP2 EMG1 HMBOX1 IKZF1 KRT31 KRT40 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP4-2 KRTAP5-9 LZTS2 MEOX2 MTUS2 NOTCH2NLA PDE4DIP PHC2 RPGRIP1 STX11 TCF4 TMCC2
Entrez ID		57096	401508
HPRD ID		05673	16982
Ensembl ID		ENSG00000092200	ENSG00000274583
Uniprot IDs		Q96KN7
PDB IDs		4QAM
Enriched GO Terms of Interacting Partners?
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