TBC1D7 and KRT19

Data Source:
BioGRID (two hybrid)

		TBC1D7	KRT19
Description		TBC1 domain family member 7	keratin 19
Image			No pdb structure
GO Annotations	Cellular Component	Cytosol Cytoplasmic Vesicle Ciliary Basal Body	Cytosol Intermediate Filament Plasma Membrane Dystrophin-associated Glycoprotein Complex Apicolateral Plasma Membrane Z Disc Sarcolemma Costamere Extracellular Exosome Cell Periphery Terminal Web
	Molecular Function	GTPase Activator Activity Protein Binding Small GTPase Binding	Structural Constituent Of Cytoskeleton Protein Binding Structural Constituent Of Muscle Protein-containing Complex Binding
	Biological Process	Positive Regulation Of Protein Ubiquitination Negative Regulation Of TOR Signaling Positive Regulation Of GTPase Activity Response To Growth Factor Activation Of GTPase Activity Negative Regulation Of Cilium Assembly	Notch Signaling Pathway Viral Process Keratinization Response To Estrogen Sarcomere Organization Cell Differentiation Involved In Embryonic Placenta Development Cornification
Pathways		TBC/RABGAPs	Keratinization Formation of the cornified envelope
Drugs
Diseases
GWAS		Migraine ( 23793025) Migraine without aura ( 23793025)
Interacting Genes		30 interacting genes: AKT1 ALOX5 APP BAG4 BLZF1 GABARAPL1 HOOK1 IKBKG INCA1 KEAP1 KRT19 KRT35 LDOC1 LNX2 LZTS1 LZTS2 MAP1LC3A MIPOL1 MMADHC NEDD4 NEDD4L PICK1 RPGRIP1 SH3GLB2 SSNA1 TRAF4 TRIM62 TSC1 XPA YWHAZ	79 interacting genes: ABI2 AMOT AMOTL2 APC ARL4A BEX2 C1orf109 CARD9 CCDC146 CCHCR1 CEP57L1 COPS4 DEPP1 DGCR6L DMD EIF4E2 EIF4ENIF1 ESR1 EXOC8 FAM107A FAM124B FANCG GFAP GLYCTK HAUS1 HGS IKZF3 KDM1A KIFC3 KRT1 KRT15 KRT2 KRT3 KRT4 KRT5 KRT6A KRT6B KRT6C KRT71 KRT72 KRT74 KRT75 KRT77 KRT78 KRT79 KRT8 KRT80 KRT81 KRT83 KRT85 KRT86 LENG1 LGALS14 NFKBID PCDHB12 PCM1 PKN1 PLEKHA5 PNN POLL POLR1C PPP1R18 PRPH PSMA1 RCOR3 SFI1 SGF29 SMARCB1 SMARCE1 SNAPIN SPG21 TBC1D7 TCHP TFPT TUBG1 UBE2I UCHL5 USHBP1 ZNF638
Entrez ID		51256	3880
HPRD ID		18165	01007
Ensembl ID		ENSG00000145979	ENSG00000171345
Uniprot IDs		A0A024QZX0 A0A024R011 Q5JPB9 Q9P0N9 U3KPY5	P08727
PDB IDs		3QWL 4Z6Y 5EJC 5ULO
Enriched GO Terms of Interacting Partners?
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