TBC1D7 and TRIM62

Data Source:
BioGRID (two hybrid)

		TBC1D7	TRIM62
Description		TBC1 domain family member 7	tripartite motif containing 62
Image			No pdb structure
GO Annotations	Cellular Component	Cytosol Cytoplasmic Vesicle Ciliary Basal Body	Cytoplasm Cytosol
	Molecular Function	GTPase Activator Activity Protein Binding Small GTPase Binding	Transcription Coactivator Activity Ubiquitin-protein Transferase Activity Protein Binding Zinc Ion Binding Identical Protein Binding Ubiquitin Protein Ligase Activity
	Biological Process	Positive Regulation Of Protein Ubiquitination Negative Regulation Of TOR Signaling Positive Regulation Of GTPase Activity Response To Growth Factor Activation Of GTPase Activity Negative Regulation Of Cilium Assembly	Negative Regulation Of Epithelial To Mesenchymal Transition Protein Ubiquitination Negative Regulation Of Viral Transcription Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Innate Immune Response Positive Regulation Of Transcription, DNA-templated Regulation Of Viral Entry Into Host Cell Positive Regulation Of DNA-binding Transcription Factor Activity Positive Regulation Of NF-kappaB Transcription Factor Activity Interferon-gamma-mediated Signaling Pathway Regulation Of Viral Release From Host Cell
Pathways		TBC/RABGAPs	Interferon gamma signaling
Drugs
Diseases
GWAS		Migraine ( 23793025) Migraine without aura ( 23793025)	Gut microbiota (beta diversity) ( 27723756)
Interacting Genes		30 interacting genes: AKT1 ALOX5 APP BAG4 BLZF1 GABARAPL1 HOOK1 IKBKG INCA1 KEAP1 KRT19 KRT35 LDOC1 LNX2 LZTS1 LZTS2 MAP1LC3A MIPOL1 MMADHC NEDD4 NEDD4L PICK1 RPGRIP1 SH3GLB2 SSNA1 TRAF4 TRIM62 TSC1 XPA YWHAZ	19 interacting genes: CARD9 EAF1 EPN2 EXOSC5 FAIM GLRX PPP1R18 SKIL SMAD2 SP7 TBC1D7 UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E3 UBE2L6 UBXN7 UTP25
Entrez ID		51256	55223
HPRD ID		18165	07697
Ensembl ID		ENSG00000145979	ENSG00000116525
Uniprot IDs		A0A024QZX0 A0A024R011 Q5JPB9 Q9P0N9 U3KPY5	Q9BVG3
PDB IDs		3QWL 4Z6Y 5EJC 5ULO
Enriched GO Terms of Interacting Partners?
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