TBC1D7 and GABARAPL1

Data Source:
BioGRID (affinity chromatography technology, pull down)

		TBC1D7	GABARAPL1
Description		TBC1 domain family member 7	GABA type A receptor associated protein like 1
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GO Annotations	Cellular Component	Cytosol Cytoplasmic Vesicle Ciliary Basal Body	Autophagosome Membrane Mitochondrion Autophagosome Endoplasmic Reticulum Golgi Apparatus Cytosol Microtubule Cytoplasmic Vesicle Membrane Dendrite Membrane Dendrite Cytoplasm Cell Body
	Molecular Function	GTPase Activator Activity Protein Binding Small GTPase Binding	Protein Binding Tat Protein Binding Ubiquitin Protein Ligase Binding Beta-tubulin Binding GABA Receptor Binding
	Biological Process	Positive Regulation Of Protein Ubiquitination Negative Regulation Of TOR Signaling Positive Regulation Of GTPase Activity Response To Growth Factor Activation Of GTPase Activity Negative Regulation Of Cilium Assembly	Autophagosome Assembly Autophagy Of Mitochondrion Cellular Response To Nitrogen Starvation Macroautophagy Autophagosome Maturation
Pathways		TBC/RABGAPs	Macroautophagy
Drugs
Diseases
GWAS		Migraine ( 23793025) Migraine without aura ( 23793025)
Interacting Genes		30 interacting genes: AKT1 ALOX5 APP BAG4 BLZF1 GABARAPL1 HOOK1 IKBKG INCA1 KEAP1 KRT19 KRT35 LDOC1 LNX2 LZTS1 LZTS2 MAP1LC3A MIPOL1 MMADHC NEDD4 NEDD4L PICK1 RPGRIP1 SH3GLB2 SSNA1 TRAF4 TRIM62 TSC1 XPA YWHAZ	73 interacting genes: AHNAK2 AMBRA1 ANK2 ATG13 ATG4A ATG4B ATG4D BNIP3L BSCL2 BSDC1 CALCOCO1 CALCOCO2 CREB3L2 CUL3 DISC1 DVL2 DYNLL1 ERBB2 ERBB3 FUNDC1 HSP90AA1 HSP90AB1 KBTBD7 KRTAP10-3 KRTAP10-7 KRTAP10-9 KXD1 MAPK15 MEFV MLX NEDD4 NFIA OPRK1 OPTN OSBPL3 PBXIP1 PSMB4 PTPRR RABGAP1 RABGAP1L RB1CC1 RCN2 RETREG3 SCYL3 SNCA SQSTM1 SRPK1 SRPK2 STRN3 TAX1BP1 TBC1D1 TBC1D10A TBC1D10B TBC1D16 TBC1D17 TBC1D2 TBC1D25 TBC1D2B TBC1D5 TBC1D7 TBC1D9 TBC1D9B THAP7 TMEM131 TNIP1 TP53INP1 TRIM21 TRIM32 ULK1 UMAD1 VDR WDFY3 ZBTB22
Entrez ID		51256	23710
HPRD ID		18165	07601
Ensembl ID		ENSG00000145979	ENSG00000139112
Uniprot IDs		A0A024QZX0 A0A024R011 Q5JPB9 Q9P0N9 U3KPY5	A0A024RAP5 Q9H0R8
PDB IDs		3QWL 4Z6Y 5EJC 5ULO	2L8J 2R2Q 5DPT 5LXH 5LXI 6HOI 6HOL
Enriched GO Terms of Interacting Partners?
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