RPGRIP1 and FEM1C

Data Source:
BioGRID (two hybrid)

		RPGRIP1	FEM1C
Description		RPGR interacting protein 1	fem-1 homolog C
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GO Annotations	Cellular Component	Axoneme Photoreceptor Connecting Cilium Ciliary Transition Zone Photoreceptor Distal Connecting Cilium	Ubiquitin Ligase Complex Nucleoplasm Cytosol
	Molecular Function	Protein Binding	Protein Binding
	Biological Process	Visual Perception Retinal Rod Cell Development Response To Stimulus Neural Precursor Cell Proliferation Non-motile Cilium Assembly	Ubiquitin-dependent Protein Catabolic Process Protein Ubiquitination Post-translational Protein Modification
Pathways			Neddylation
Drugs
Diseases		Leber congenital amaurosis (LCR) Cone-rod dystrophy and cone dystrophy, including: Cone-rod dystrophy (CORD); Cone dystrophy (COD); Retinal cone dystrophy (RCD)
GWAS		Body mass index ( 26426971) Body mass index (age>50) ( 26426971) Body mass index x sex x age interaction (4df test) ( 26426971) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Height ( 31562340) Refractive error ( 32231278) Superior temporal sulcus banks volume ( 31530798)	Conotruncal heart defects (inherited effects) ( 28468790) Response to antidepressants (symptom improvement) ( 29160301)
Interacting Genes		26 interacting genes: AEN BRCA1 CBX8 CCDC146 CHCHD3 CSPP1 DPPA4 FAM74A4 FEM1C GATAD2B HEYL IQCE MAGEB2 NPHP4 PTF1A RNF6 RPGR RPP25L SCNM1 TBC1D7 TFPT TRIB3 ZNF337 ZNF417 ZNF564 ZNF688	7 interacting genes: BCL2L11 CEP63 LZTS2 MALT1 MCM8 PNMA1 RPGRIP1
Entrez ID		57096	56929
HPRD ID		05673	16384
Ensembl ID		ENSG00000092200	ENSG00000145780
Uniprot IDs		Q96KN7	Q96JP0
PDB IDs		4QAM	6LBG 6LBN 6LDP 6LE6 6LEN 6LEY 6LF0 6XKC 7JYA
Enriched GO Terms of Interacting Partners?
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