MAST1 and RAB3D

Data Source:
BioGRID (two hybrid)

		MAST1	RAB3D
Description		microtubule associated serine/threonine kinase 1	RAB3D, member RAS oncogene family
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GO Annotations	Cellular Component	Cytoplasm Cytoskeleton Plasma Membrane Axon Dendrite Neuron Projection Neuronal Cell Body	Endosome Cytoplasmic Microtubule Plasma Membrane Synaptic Vesicle Azurophil Granule Membrane Zymogen Granule Extracellular Exosome Secretory Vesicle
	Molecular Function	Magnesium Ion Binding Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Microtubule Binding Protein Serine Kinase Activity Protein Threonine Kinase Activity	GTPase Activity Protein Binding GTP Binding GTP-dependent Protein Binding Myosin V Binding
	Biological Process	Protein Phosphorylation Cytoskeleton Organization Brain Development Peptidyl-serine Phosphorylation Intracellular Signal Transduction	Vesicle Docking Involved In Exocytosis Protein Secretion Regulation Of Exocytosis Peptidyl-cysteine Methylation Neutrophil Degranulation Bone Resorption Protein Localization To Plasma Membrane Positive Regulation Of Regulated Secretory Pathway
Pathways			Neutrophil degranulation RAB geranylgeranylation
Drugs		Fostamatinib
Diseases
GWAS		High light scatter reticulocyte count ( 27863252) High light scatter reticulocyte percentage of red cells ( 32888494 27863252) Immature fraction of reticulocytes ( 32888494) Intelligence (MTAG) ( 29326435) Mean corpuscular hemoglobin ( 29403010 32888494) Mean corpuscular volume ( 32888494) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Monocyte count ( 27863252) Red blood cell count ( 29403010) Reticulocyte fraction of red cells ( 32888494)	Early cardiac repolarization ( 31600170) HDL cholesterol ( 23505323)
Interacting Genes		40 interacting genes: A2M AP1M2 APOE APP BLMH CDK5 CYP2C8 CYP2C9 DNAJB1 ECSIT EGFR ELAVL3 EXOC6 EXOSC1 FBXL12 FBXW4 GCDH HSP90AB1 IFIT3 IFIT5 LONP1 LOXL4 NOS3 OGA PAXIP1 PRAM1 PRDX2 PSEN2 PTEN RAB3A RAB3D RAD23A RNF32 RNLS RPP30 RPS6KA1 SNTA1 SNTB2 STAMBPL1 UBE2D3	15 interacting genes: AKT1 AKT2 AP1M2 APP CEP55 CHM CYP2C9 MAST1 RAB3IP RABIF RIMS2 RNF32 RPH3AL SYTL4 VRTN
Entrez ID		22983	9545
HPRD ID		17469	05070
Ensembl ID		ENSG00000105613	ENSG00000105514
Uniprot IDs		Q9Y2H9	A0A024R7G2 O95716
PDB IDs		2M9X 3PS4	2GF9
Enriched GO Terms of Interacting Partners?
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